| 2020-Wake Forest (ACC) |
| Sep. 12 | vs | *Clemson (10-2) | L | 13 | 37 |
| Sep. 19 | at | *North Carolina State (8-4) | L | 42 | 45 |
| Oct. 2 | vs | Campbell ( ) | W | 66 | 14 |
| Oct. 17 | vs | *Virginia (5-5) | W | 40 | 23 |
| Oct. 24 | vs | *Virginia Tech (5-6) | W | 23 | 16 |
| Oct. 31 | at | *Syracuse (1-10) | W | 38 | 14 |
| Nov. 14 | at | *North Carolina (8-4) | L | 53 | 59 |
| Dec. 12 | at | *Louisville (4-7) | L | 21 | 45 |
| Dec. 30 | vs | Wisconsin (4-3) | L | 28 | 42 | at Charlotte, NC | Duke's Mayo Bowl |
| | 4-5-0 | | 324 | 295 |
| 2019-Wake Forest (ACC) |
| Aug. 30 | vs | Utah State (7-6) | W | 38 | 35 |
| Sep. 6 | at | Rice (3-9) | W | 41 | 21 |
| Sep. 13 | vs | *North Carolina (7-6) | W | 24 | 18 |
| Sep. 21 | vs | Elon ( ) | W | 49 | 7 |
| Sep. 28 | at | *Boston College (6-7) | W | 27 | 24 |
| Oct. 12 | vs | *Louisville (8-5) | L | 59 | 62 |
| Oct. 19 | vs | *Florida State (6-7) | W | 22 | 20 |
| Nov. 2 | vs | *North Carolina State (4-8) | W | 44 | 10 |
| Nov. 9 | at | *Virginia Tech (8-5) | L | 17 | 36 |
| Nov. 16 | at | *Clemson (14-1) | L | 3 | 52 |
| Nov. 23 | vs | *Duke (5-7) | W | 39 | 27 |
| Nov. 30 | at | *Syracuse (5-7) | L | 30 | 39 |
| Dec. 27 | vs | Michigan State (7-6) | L | 21 | 27 | at New York, NY | Pinstripe Bowl |
| | 8-5-0 | | 414 | 378 |
| 2018-Wake Forest (ACC) |
| Aug. 30 | at | Tulane (7-6) | W | 23 | 17 |
| Sep. 8 | vs | Towson ( ) | W | 51 | 20 |
| Sep. 13 | vs | *Boston College (7-5) | L | 34 | 41 |
| Sep. 22 | vs | Notre Dame (12-1) | L | 27 | 56 |
| Sep. 29 | vs | Rice (2-11) | W | 56 | 24 |
| Oct. 6 | vs | *Clemson (15-0) | L | 3 | 63 |
| Oct. 20 | at | *Florida State (5-7) | L | 17 | 38 |
| Oct. 27 | at | *Louisville (2-10) | W | 56 | 35 |
| Nov. 3 | vs | *Syracuse (10-3) | L | 24 | 41 |
| Nov. 8 | at | *North Carolina State (9-4) | W | 27 | 23 |
| Nov. 17 | vs | *Pittsburgh (7-7) | L | 13 | 34 |
| Nov. 24 | at | *Duke (8-5) | W | 59 | 7 |
| Dec. 22 | vs | Memphis (8-6) | W | 37 | 34 | at Birmingham, AL | Birmingham Bowl |
| | 7-6-0 | | 427 | 433 |
| 2017-Wake Forest (ACC) |
| Aug. 31 | vs | Presbyterian ( ) | W | 51 | 7 |
| Sep. 9 | at | *Boston College (7-6) | W | 34 | 10 |
| Sep. 16 | vs | Utah State (6-7) | W | 46 | 10 |
| Sep. 23 | at | Appalachian State (9-4) | W | 20 | 19 |
| Sep. 30 | vs | *Florida State (7-6) | L | 19 | 26 |
| Oct. 7 | at | *Clemson (12-2) | L | 14 | 28 |
| Oct. 21 | at | *Georgia Tech (5-6) | L | 24 | 38 |
| Oct. 28 | vs | *Louisville (8-5) | W | 42 | 32 |
| Nov. 4 | at | Notre Dame (10-3) | L | 37 | 48 |
| Nov. 11 | at | *Syracuse (4-8) | W | 64 | 43 |
| Nov. 18 | vs | *North Carolina State (9-4) | W | 30 | 24 |
| Nov. 25 | vs | *Duke (7-6) | L | 23 | 31 |
| Dec. 29 | vs | Texas A&M (7-6) | W | 55 | 52 | at Charlotte, NC | Belk Bowl |
| | 8-5-0 | | 459 | 368 |
| 2016-Wake Forest (ACC) |
| Sep. 1 | vs | Tulane (4-8) | W | 7 | 3 |
| Sep. 10 | at | *Duke (4-8) | W | 24 | 14 |
| Sep. 17 | vs | Delaware ( ) | W | 38 | 21 |
| Sep. 24 | at | Indiana (6-7) | W | 33 | 28 |
| Oct. 1 | at | *North Carolina State (7-6) | L | 16 | 33 |
| Oct. 8 | vs | *Syracuse (4-8) | W | 28 | 9 |
| Oct. 15 | at | *Florida State (10-3) | L | 6 | 17 |
| Oct. 29 | vs | Army (8-5) | L | 13 | 21 |
| Nov. 5 | vs | *Virginia (2-10) | W | 27 | 20 |
| Nov. 12 | at | *Louisville (9-4) | L | 12 | 44 |
| Nov. 19 | vs | *Clemson (14-1) | L | 13 | 35 |
| Nov. 26 | vs | *Boston College (7-6) | L | 14 | 17 |
| Dec. 27 | vs | Temple (10-4) | W | 34 | 26 | at Annapolis, MD | Military Bowl |
| | 7-6-0 | | 265 | 288 |
| 2015-Wake Forest (ACC) |
| Sep. 3 | vs | Elon ( ) | W | 41 | 3 |
| Sep. 12 | at | *Syracuse (4-8) | L | 17 | 30 |
| Sep. 19 | at | Army (2-10) | W | 17 | 14 |
| Sep. 26 | vs | Indiana (6-7) | L | 24 | 31 |
| Oct. 3 | vs | *Florida State (10-3) | L | 16 | 24 |
| Oct. 10 | at | *Boston College (3-9) | W | 3 | 0 |
| Oct. 17 | at | *North Carolina (11-3) | L | 14 | 50 |
| Oct. 24 | vs | *North Carolina State (7-6) | L | 17 | 35 |
| Oct. 30 | vs | *Louisville (8-5) | L | 19 | 20 |
| Nov. 14 | at | Notre Dame (10-3) | L | 7 | 28 |
| Nov. 21 | at | *Clemson (14-1) | L | 13 | 33 |
| Nov. 28 | vs | *Duke (8-5) | L | 21 | 27 |
| | 3-9-0 | | 209 | 295 |
| 2014-Wake Forest (ACC) |
| Aug. 28 | at | Louisiana-Monroe (4-8) | L | 10 | 17 |
| Sep. 6 | vs | Gardner-Webb ( ) | W | 23 | 6 |
| Sep. 13 | at | Utah State (10-4) | L | 24 | 36 |
| Sep. 20 | vs | Army (4-8) | W | 24 | 21 |
| Sep. 27 | at | *Louisville (9-4) | L | 10 | 20 |
| Oct. 4 | at | *Florida State (13-1) | L | 3 | 43 |
| Oct. 18 | vs | *Syracuse (3-9) | L | 7 | 30 |
| Oct. 25 | vs | *Boston College (7-6) | L | 17 | 23 |
| Nov. 6 | vs | *Clemson (10-3) | L | 20 | 34 |
| Nov. 15 | at | *North Carolina State (8-5) | L | 13 | 42 |
| Nov. 22 | vs | *Virginia Tech (7-6) | W | 6 | 3 |
| Nov. 29 | at | *Duke (9-4) | L | 21 | 41 |
| | 3-9-0 | | 178 | 316 |
| 2013-Wake Forest (ACC) |
| Aug. 29 | vs | Presbyterian ( ) | W | 31 | 7 |
| Sep. 6 | at | *Boston College (7-6) | L | 10 | 24 |
| Sep. 14 | vs | Louisiana-Monroe (6-6) | L | 19 | 21 |
| Sep. 21 | at | Army (3-9) | W | 25 | 11 |
| Sep. 28 | at | *Clemson (11-2) | L | 7 | 56 |
| Oct. 5 | vs | *North Carolina State (3-9) | W | 28 | 13 |
| Oct. 19 | vs | *Maryland (7-6) | W | 34 | 10 |
| Oct. 26 | at | *Miami (Florida) (9-4) | L | 21 | 24 |
| Nov. 2 | at | *Syracuse (7-6) | L | 0 | 13 |
| Nov. 9 | vs | *Florida State (14-0) | L | 3 | 59 |
| Nov. 23 | vs | *Duke (10-4) | L | 21 | 28 |
| Nov. 30 | at | Vanderbilt (9-4) | L | 21 | 23 |
| | 4-8-0 | | 220 | 289 |
| 2012-Wake Forest (ACC) |
| Sep. 1 | vs | Liberty ( ) | W | 20 | 17 |
| Sep. 8 | vs | *North Carolina (8-4) | W | 28 | 27 |
| Sep. 15 | at | *Florida State (12-2) | L | 0 | 52 |
| Sep. 22 | vs | Army (2-10) | W | 49 | 37 |
| Sep. 29 | vs | *Duke (6-7) | L | 27 | 34 |
| Oct. 6 | at | *Maryland (4-8) | L | 14 | 19 |
| Oct. 20 | at | *Virginia (4-8) | W | 16 | 10 |
| Oct. 25 | vs | *Clemson (11-2) | L | 13 | 42 |
| Nov. 3 | vs | *Boston College (2-10) | W | 28 | 14 |
| Nov. 10 | at | *North Carolina State (7-6) | L | 6 | 37 |
| Nov. 17 | at | Notre Dame (12-1) | L | 0 | 38 |
| Nov. 24 | vs | Vanderbilt (9-4) | L | 21 | 55 |
| | 5-7-0 | | 222 | 382 |
| 2011-Wake Forest (ACC) |
| Sep. 1 | at | Syracuse (5-7) | L | 29 | 36 |
| Sep. 10 | vs | *North Carolina State (8-5) | W | 34 | 27 |
| Sep. 17 | vs | Gardner-Webb ( ) | W | 48 | 5 |
| Oct. 1 | at | *Boston College (4-8) | W | 27 | 19 |
| Oct. 8 | vs | *Florida State (9-4) | W | 35 | 30 |
| Oct. 15 | vs | *Virginia Tech (11-3) | L | 17 | 38 |
| Oct. 22 | at | *Duke (3-9) | W | 24 | 23 |
| Oct. 29 | at | *North Carolina (7-6) | L | 24 | 49 |
| Nov. 5 | vs | Notre Dame (8-5) | L | 17 | 24 |
| Nov. 12 | at | *Clemson (10-4) | L | 28 | 31 |
| Nov. 19 | vs | *Maryland (2-10) | W | 31 | 10 |
| Nov. 26 | vs | Vanderbilt (6-7) | L | 7 | 41 |
| Dec. 30 | vs | Mississippi State (7-6) | L | 17 | 23 | at Nashville, TN | Music City Bowl |
| | 6-7-0 | | 338 | 356 |
| 2010-Wake Forest (ACC) |
| Sep. 2 | vs | Presbyterian ( ) | W | 53 | 13 |
| Sep. 11 | vs | *Duke (3-9) | W | 54 | 48 |
| Sep. 18 | at | Stanford (12-1) | L | 24 | 68 |
| Sep. 25 | at | *Florida State (10-4) | L | 0 | 31 |
| Oct. 2 | vs | *Georgia Tech (6-7) | L | 20 | 24 |
| Oct. 9 | vs | Navy (9-4) | L | 27 | 28 |
| Oct. 16 | at | *Virginia Tech (11-3) | L | 21 | 52 |
| Oct. 30 | at | *Maryland (9-4) | L | 14 | 62 |
| Nov. 6 | vs | *Boston College (7-6) | L | 13 | 23 |
| Nov. 13 | at | *North Carolina State (9-4) | L | 3 | 38 |
| Nov. 20 | vs | *Clemson (6-7) | L | 10 | 30 |
| Nov. 27 | at | Vanderbilt (2-10) | W | 34 | 13 |
| | 3-9-0 | | 273 | 430 |
| 2009-Wake Forest (ACC) |
| Sep. 5 | vs | Baylor (4-8) | L | 21 | 24 |
| Sep. 12 | vs | Stanford (8-5) | W | 24 | 17 |
| Sep. 19 | vs | Elon ( ) | W | 35 | 7 |
| Sep. 26 | at | *Boston College (8-5) | L | 24 | 27 |
| Oct. 3 | vs | *North Carolina State (5-7) | W | 30 | 24 |
| Oct. 10 | vs | *Maryland (2-10) | W | 42 | 32 |
| Oct. 17 | at | *Clemson (9-5) | L | 3 | 38 |
| Oct. 24 | at | Navy (10-4) | L | 10 | 13 |
| Oct. 31 | vs | *Miami (Florida) (9-4) | L | 27 | 28 |
| Nov. 7 | at | *Georgia Tech (11-3) | L | 27 | 30 |
| Nov. 14 | vs | *Florida State (7-6) | L | 28 | 41 |
| Nov. 28 | at | *Duke (5-7) | W | 45 | 34 |
| | 5-7-0 | | 316 | 315 |
| 2008-Wake Forest (ACC) |
| Aug. 28 | at | Baylor (4-8) | W | 41 | 13 |
| Sep. 6 | vs | Mississippi (9-4) | W | 30 | 28 |
| Sep. 20 | at | *Florida State (9-4) | W | 12 | 3 |
| Sep. 27 | vs | Navy (8-5) | L | 17 | 24 |
| Oct. 9 | vs | *Clemson (7-6) | W | 12 | 7 |
| Oct. 18 | at | *Maryland (8-5) | L | 0 | 26 |
| Oct. 25 | at | *Miami (Florida) (7-6) | L | 10 | 16 |
| Nov. 1 | vs | *Duke (4-8) | W | 33 | 30 |
| Nov. 8 | vs | *Virginia (5-7) | W | 28 | 17 |
| Nov. 15 | at | *North Carolina State (6-7) | L | 17 | 21 |
| Nov. 22 | vs | *Boston College (9-5) | L | 21 | 24 |
| Nov. 29 | vs | Vanderbilt (7-6) | W | 23 | 10 |
| Dec. 20 | vs | Navy (8-5) | W | 29 | 19 | at Washington, DC | EagleBank Bowl |
| | 8-5-0 | | 273 | 238 |
| 2007-Wake Forest (ACC) |
| Sep. 1 | at | *Boston College (11-3) | L | 28 | 38 |
| Sep. 8 | vs | Nebraska (5-7) | L | 17 | 20 |
| Sep. 15 | vs | Army (3-9) | W | 21 | 10 |
| Sep. 22 | vs | *Maryland (6-7) | W | 31 | 24 |
| Oct. 6 | at | *Duke (1-11) | W | 41 | 36 |
| Oct. 11 | vs | *Florida State (7-6) | W | 24 | 21 |
| Oct. 20 | at | Navy (8-5) | W | 44 | 24 |
| Oct. 27 | vs | *North Carolina (4-8) | W | 37 | 10 |
| Nov. 3 | at | *Virginia (9-4) | L | 16 | 17 |
| Nov. 10 | at | *Clemson (9-4) | L | 10 | 44 |
| Nov. 17 | vs | *North Carolina State (5-7) | W | 38 | 18 |
| Nov. 24 | at | Vanderbilt (5-7) | W | 31 | 17 |
| Dec. 29 | vs | Connecticut (9-4) | W | 24 | 10 | at Charlotte, NC | Meineke Car Care Bowl |
| | 9-4-0 | | 362 | 289 |
| 2006-Wake Forest (ACC) |
| Sep. 2 | vs | Syracuse (4-8) | W | 20 | 10 |
| Sep. 9 | vs | *Duke (0-12) | W | 14 | 13 |
| Sep. 16 | at | Connecticut (4-8) | W | 24 | 13 |
| Sep. 23 | at | Mississippi (4-8) | W | 27 | 3 |
| Sep. 30 | vs | Liberty ( ) | W | 34 | 14 |
| Oct. 7 | vs | *Clemson (8-5) | L | 17 | 27 |
| Oct. 14 | at | *North Carolina State (3-9) | W | 25 | 23 |
| Oct. 28 | at | *North Carolina (3-9) | W | 24 | 17 |
| Nov. 4 | vs | *Boston College (10-3) | W | 21 | 14 |
| Nov. 11 | at | *Florida State (7-6) | W | 30 | 0 |
| Nov. 18 | vs | *Virginia Tech (10-3) | L | 6 | 27 |
| Nov. 25 | at | *Maryland (9-4) | W | 38 | 24 |
| Dec. 2 | vs | *Georgia Tech (9-5) | W | 9 | 6 | at Jacksonville, FL | ACC Championship |
| Jan. 2 | vs | Louisville (12-1) | L | 13 | 24 | at Miami, FL | Orange Bowl |
| | 11-3-0 | | 302 | 215 |
| 2005-Wake Forest (ACC) |
| Sep. 1 | vs | Vanderbilt (5-6) | L | 20 | 24 |
| Sep. 10 | at | Nebraska (8-4) | L | 3 | 31 |
| Sep. 17 | vs | East Carolina (5-6) | W | 44 | 34 |
| Sep. 24 | vs | *Maryland (5-6) | L | 12 | 22 |
| Oct. 1 | vs | *Clemson (8-4) | W | 31 | 27 |
| Oct. 8 | at | *Florida State (8-5) | L | 24 | 41 |
| Oct. 15 | at | *Boston College (9-3) | L | 30 | 35 |
| Oct. 22 | vs | *North Carolina State (7-5) | W | 27 | 19 |
| Oct. 29 | at | *Duke (1-10) | W | 44 | 6 |
| Nov. 5 | at | *Georgia Tech (7-5) | L | 17 | 30 |
| Nov. 12 | vs | *Miami (Florida) (9-3) | L | 17 | 47 |
| | 4-7-0 | | 269 | 316 |
| 2004-Wake Forest (ACC) |
| Sep. 4 | at | *Clemson (6-5) | L | 30 | 37 |
| Sep. 11 | at | East Carolina (2-9) | W | 31 | 17 |
| Sep. 18 | vs | North Carolina A&T ( ) | W | 42 | 3 |
| Sep. 25 | vs | Boston College (9-3) | W | 17 | 14 |
| Oct. 2 | at | *North Carolina State (5-6) | L | 21 | 27 |
| Oct. 9 | vs | *Virginia Tech (10-3) | L | 10 | 17 |
| Oct. 23 | vs | *Florida State (9-3) | L | 17 | 20 |
| Oct. 30 | vs | *Duke (2-9) | W | 24 | 22 |
| Nov. 13 | vs | *North Carolina (6-6) | L | 24 | 31 |
| Nov. 20 | at | *Miami (Florida) (9-3) | L | 7 | 52 |
| Nov. 27 | at | *Maryland (5-6) | L | 7 | 13 |
| | 4-7-0 | | 230 | 253 |
| 2003-Wake Forest (ACC) |
| Aug. 30 | at | Boston College (8-5) | W | 32 | 28 |
| Sep. 6 | vs | *North Carolina State (8-5) | W | 38 | 24 |
| Sep. 13 | vs | Purdue (9-4) | L | 10 | 16 |
| Sep. 20 | vs | East Carolina (1-11) | W | 34 | 16 |
| Sep. 27 | at | *Virginia (8-5) | L | 24 | 27 |
| Oct. 11 | vs | *Georgia Tech (7-6) | L | 7 | 24 |
| Oct. 18 | at | *Duke (4-8) | W | 42 | 13 |
| Oct. 25 | at | *Florida State (10-3) | L | 24 | 48 |
| Nov. 1 | vs | *Clemson (9-4) | W | 45 | 17 |
| Nov. 8 | at | *North Carolina (2-10) | L | 34 | 42 |
| Nov. 15 | vs | Connecticut (9-3) | L | 17 | 51 |
| Nov. 29 | vs | *Maryland (10-3) | L | 28 | 41 |
| | 5-7-0 | | 335 | 347 |
| 2002-Wake Forest (ACC) |
| Aug. 29 | at | Northern Illinois (8-4) | L | 41 | 42 |
| Sep. 7 | vs | East Carolina (4-8) | W | 27 | 22 |
| Sep. 14 | at | *North Carolina State (11-3) | L | 13 | 32 |
| Sep. 21 | at | Purdue (7-6) | W | 24 | 21 |
| Sep. 28 | vs | *Virginia (9-5) | L | 34 | 38 |
| Oct. 5 | at | *Georgia Tech (7-6) | W | 24 | 21 |
| Oct. 12 | vs | *Duke (2-10) | W | 36 | 10 |
| Oct. 19 | at | *Clemson (7-6) | L | 23 | 31 |
| Oct. 26 | vs | *North Carolina (3-9) | W | 31 | 0 |
| Nov. 2 | vs | *Florida State (9-5) | L | 21 | 34 |
| Nov. 23 | vs | Navy (2-10) | W | 30 | 27 |
| Nov. 30 | at | *Maryland (11-3) | L | 14 | 32 |
| Dec. 30 | vs | Oregon (7-6) | W | 38 | 17 | at Seattle, WA | Seattle Bowl |
| | 7-6-0 | | 356 | 327 |
| 2001-Wake Forest (ACC) |
| Sep. 1 | at | East Carolina (6-6) | W | 21 | 19 |
| Sep. 8 | vs | Appalachian State ( ) | W | 20 | 10 |
| Sep. 22 | vs | *Maryland (10-2) | L | 20 | 27 |
| Sep. 29 | at | *Florida State (8-4) | L | 24 | 48 |
| Oct. 6 | vs | *North Carolina State (7-5) | L | 14 | 17 |
| Oct. 13 | at | *Duke (0-11) | W | 42 | 35 |
| Oct. 27 | vs | *Clemson (7-5) | L | 14 | 21 |
| Nov. 3 | at | *Virginia (5-7) | W | 34 | 30 |
| Nov. 10 | at | *North Carolina (8-5) | W | 32 | 31 |
| Nov. 17 | vs | *Georgia Tech (8-5) | L | 33 | 38 |
| Nov. 24 | vs | Northern Illinois (6-5) | W | 38 | 35 |
| | 6-5-0 | | 292 | 311 |
| 2000-Wake Forest (ACC) |
| Aug. 31 | vs | Appalachian State ( ) | L | 16 | 20 |
| Sep. 9 | vs | *North Carolina (6-5) | L | 14 | 35 |
| Sep. 16 | at | *Clemson (9-3) | L | 7 | 55 |
| Sep. 30 | vs | *Virginia (6-6) | L | 10 | 27 |
| Oct. 7 | vs | Vanderbilt (3-8) | L | 10 | 17 |
| Oct. 14 | at | *Georgia Tech (9-3) | L | 20 | 52 |
| Oct. 21 | at | *Maryland (5-6) | L | 7 | 37 |
| Nov. 4 | vs | *Duke (0-11) | W | 28 | 26 |
| Nov. 11 | vs | *Florida State (11-2) | L | 6 | 35 |
| Nov. 18 | at | Navy (1-10) | W | 49 | 26 |
| Nov. 25 | at | *North Carolina State (8-4) | L | 14 | 32 |
| | 2-9-0 | | 181 | 362 |
| 1999-Wake Forest (ACC) |
| Sep. 11 | at | Army (3-8) | W | 34 | 15 |
| Sep. 18 | at | *Virginia (7-5) | L | 7 | 35 |
| Sep. 25 | vs | *North Carolina State (6-6) | W | 31 | 7 |
| Oct. 2 | vs | Rutgers (1-10) | W | 17 | 10 |
| Oct. 9 | vs | *Maryland (5-6) | L | 14 | 17 |
| Oct. 16 | at | *Florida State (12-0) | L | 10 | 33 |
| Oct. 23 | vs | Alabama-Birmingham (5-6) | W | 47 | 3 |
| Oct. 30 | vs | *Clemson (6-6) | L | 3 | 12 |
| Nov. 6 | at | *North Carolina (3-8) | W | 19 | 3 |
| Nov. 13 | at | *Duke (3-8) | L | 35 | 48 |
| Nov. 20 | vs | *Georgia Tech (8-4) | W | 26 | 23 |
| Dec. 25 | vs | Arizona State (6-6) | W | 23 | 3 | at Honolulu, HI | Aloha Classic |
| | 7-5-0 | | 266 | 209 |
| 1998-Wake Forest (ACC) |
| Sep. 5 | at | Air Force (12-1) | L | 0 | 42 |
| Sep. 10 | vs | Navy (3-8) | W | 26 | 14 |
| Sep. 26 | at | *Clemson (3-8) | W | 29 | 19 |
| Oct. 3 | vs | Appalachian State ( ) | L | 27 | 30 |
| Oct. 10 | vs | *Duke (4-7) | L | 16 | 19 |
| Oct. 17 | at | *Maryland (3-8) | W | 20 | 10 |
| Oct. 24 | vs | *North Carolina (7-5) | L | 31 | 38 |
| Oct. 31 | vs | *Virginia (9-3) | L | 17 | 38 |
| Nov. 7 | at | *North Carolina State (7-5) | L | 27 | 38 |
| Nov. 14 | vs | *Florida State (11-2) | L | 7 | 24 |
| Nov. 21 | at | *Georgia Tech (10-2) | L | 35 | 63 |
| | 3-8-0 | | 235 | 335 |
| 1997-Wake Forest (ACC) |
| Sep. 6 | vs | Northwestern (5-7) | W | 27 | 20 |
| Sep. 13 | at | East Carolina (5-6) | L | 24 | 25 |
| Sep. 20 | vs | *Georgia Tech (7-5) | L | 26 | 28 |
| Sep. 25 | vs | *North Carolina State (6-5) | W | 19 | 18 |
| Oct. 4 | at | *Virginia (7-4) | L | 13 | 21 |
| Oct. 11 | at | *North Carolina (11-1) | L | 12 | 30 |
| Oct. 18 | vs | *Maryland (2-9) | W | 35 | 17 |
| Oct. 25 | at | *Duke (2-9) | W | 38 | 24 |
| Nov. 1 | vs | *Clemson (7-5) | L | 16 | 33 |
| Nov. 8 | at | Rutgers (0-11) | W | 28 | 14 |
| Nov. 15 | at | *Florida State (11-1) | L | 7 | 58 |
| | 5-6-0 | | 245 | 288 |
| 1996-Wake Forest (ACC) |
| Aug. 29 | vs | Appalachian State ( ) | W | 19 | 13 |
| Sep. 7 | vs | Northwestern (9-3) | W | 28 | 27 |
| Sep. 14 | at | *Georgia Tech (5-6) | L | 10 | 30 |
| Sep. 21 | vs | *Virginia (7-5) | L | 7 | 42 |
| Sep. 28 | at | *Clemson (7-5) | L | 10 | 21 |
| Oct. 5 | vs | *North Carolina (10-2) | L | 6 | 45 |
| Oct. 19 | at | *Maryland (5-6) | L | 0 | 52 |
| Oct. 26 | vs | Navy (9-3) | L | 18 | 47 |
| Nov. 9 | vs | *Florida State (11-1) | L | 7 | 44 | at Orlando, FL |
| Nov. 16 | vs | *Duke (0-11) | W | 17 | 16 |
| Nov. 23 | at | *North Carolina State (3-8) | L | 22 | 37 |
| | 3-8-0 | | 144 | 374 |
| 1995-Wake Forest (ACC) |
| Aug. 31 | vs | Appalachian State ( ) | L | 22 | 24 |
| Sep. 9 | at | Tulane (2-9) | L | 9 | 35 |
| Sep. 16 | vs | *Clemson (8-4) | L | 14 | 29 |
| Sep. 23 | at | Navy (5-6) | W | 30 | 7 |
| Sep. 30 | at | *Virginia (9-4) | L | 17 | 35 |
| Oct. 7 | vs | *Maryland (6-5) | L | 6 | 9 |
| Oct. 14 | at | *Florida State (10-2) | L | 13 | 72 |
| Oct. 21 | at | *North Carolina (7-5) | L | 7 | 31 |
| Oct. 28 | at | *Duke (3-8) | L | 26 | 42 |
| Nov. 4 | vs | *Georgia Tech (6-5) | L | 23 | 24 |
| Nov. 18 | vs | *North Carolina State (3-8) | L | 23 | 52 |
| | 1-10-0 | | 190 | 360 |
| 1994-Wake Forest (ACC) |
| Sep. 3 | at | Vanderbilt (5-6) | L | 14 | 35 |
| Sep. 10 | vs | Appalachian State ( ) | W | 12 | 10 |
| Sep. 17 | vs | *Florida State (10-1-1) | L | 14 | 56 |
| Sep. 24 | at | *Maryland (4-7) | L | 7 | 31 |
| Oct. 1 | vs | Army (4-7) | W | 33 | 27 |
| Oct. 8 | vs | *Virginia (9-3) | L | 6 | 42 |
| Oct. 15 | at | *North Carolina State (9-3) | L | 3 | 34 |
| Oct. 22 | vs | *Duke (8-4) | L | 26 | 51 |
| Oct. 29 | at | *Clemson (5-6) | L | 8 | 24 |
| Nov. 12 | vs | *North Carolina (8-4) | L | 0 | 50 |
| Nov. 19 | at | *Georgia Tech (1-10) | W | 20 | 13 |
| | 3-8-0 | | 143 | 373 |
| 1993-Wake Forest (ACC) |
| Sep. 4 | vs | Vanderbilt (4-7) | L | 12 | 27 |
| Sep. 11 | vs | *North Carolina State (7-5) | L | 16 | 34 |
| Sep. 18 | vs | Appalachian State ( ) | W | 20 | 3 |
| Sep. 25 | at | Northwestern (2-9) | L | 14 | 26 |
| Oct. 9 | at | *North Carolina (10-3) | L | 35 | 45 |
| Oct. 16 | at | *Clemson (9-3) | W | 20 | 16 |
| Oct. 23 | vs | *Duke (3-8) | L | 13 | 21 |
| Oct. 30 | at | *Florida State (12-1) | L | 0 | 54 |
| Nov. 6 | at | *Virginia (7-5) | L | 9 | 21 |
| Nov. 13 | vs | *Georgia Tech (5-6) | L | 28 | 38 |
| Nov. 20 | vs | *Maryland (2-9) | L | 32 | 33 |
| | 2-9-0 | | 199 | 318 |
| 1992-Wake Forest (ACC) |
| Sep. 5 | vs | *North Carolina (9-3) | L | 17 | 35 |
| Sep. 12 | vs | Appalachian State ( ) | W | 10 | 7 |
| Sep. 26 | at | *Florida State (11-1) | L | 7 | 35 |
| Oct. 3 | vs | *Virginia (7-4) | L | 17 | 31 |
| Oct. 10 | at | Vanderbilt (4-7) | W | 40 | 6 |
| Oct. 17 | at | *Maryland (3-8) | W | 30 | 23 |
| Oct. 24 | vs | Army (5-6) | W | 23 | 7 |
| Oct. 31 | vs | *Clemson (5-6) | W | 18 | 15 |
| Nov. 7 | at | *Duke (2-9) | W | 28 | 14 |
| Nov. 14 | at | *Georgia Tech (5-6) | W | 23 | 10 |
| Nov. 21 | at | *North Carolina State (9-3-1) | L | 14 | 42 |
| Dec. 31 | vs | Oregon (6-6) | W | 39 | 35 | at Shreveport, LA | Independence Bowl |
| | 8-4-0 | | 266 | 260 |
| 1991-Wake Forest (ACC) |
| Sep. 14 | vs | Western Carolina ( ) | W | 40 | 24 |
| Sep. 21 | vs | *North Carolina State (9-3) | L | 3 | 30 |
| Sep. 28 | at | Northwestern (3-8) | L | 14 | 41 |
| Oct. 5 | vs | Appalachian State ( ) | L | 3 | 17 |
| Oct. 12 | at | *North Carolina (7-4) | L | 10 | 24 |
| Oct. 19 | vs | *Maryland (2-9) | L | 22 | 23 |
| Oct. 26 | at | *Virginia (8-3-1) | L | 7 | 48 |
| Nov. 2 | at | *Clemson (9-2-1) | L | 10 | 28 |
| Nov. 9 | vs | *Duke (4-6-1) | W | 31 | 14 |
| Nov. 16 | at | *Georgia Tech (8-5) | L | 3 | 27 |
| Nov. 23 | at | Navy (1-10) | W | 52 | 24 |
| | 3-8-0 | | 195 | 300 |
| 1990-Wake Forest (ACC) |
| Sep. 1 | at | Rice (5-6) | L | 17 | 33 |
| Sep. 8 | vs | Appalachian State ( ) | W | 23 | 12 |
| Sep. 15 | at | *North Carolina State (7-5) | L | 15 | 20 |
| Sep. 29 | vs | Army (6-5) | W | 52 | 14 |
| Oct. 6 | vs | *North Carolina (6-4-1) | L | 24 | 31 |
| Oct. 13 | at | *Maryland (6-5-1) | L | 13 | 41 |
| Oct. 20 | vs | *Virginia (8-4) | L | 14 | 49 |
| Oct. 27 | vs | *Clemson (10-2) | L | 6 | 24 |
| Nov. 3 | at | *Duke (4-7) | L | 20 | 57 |
| Nov. 17 | vs | *Georgia Tech (11-0-1) | L | 7 | 42 |
| Nov. 24 | at | Vanderbilt (1-10) | W | 56 | 28 |
| | 3-8-0 | | 247 | 351 |
| 1989-Wake Forest (ACC) |
| Sep. 9 | vs | Appalachian State ( ) | L | 10 | 15 |
| Sep. 16 | vs | *North Carolina State (7-5) | L | 17 | 27 |
| Sep. 23 | at | Army (6-5) | L | 10 | 14 |
| Sep. 30 | vs | Rice (2-8-1) | T | 17 | 17 |
| Oct. 7 | at | *North Carolina (1-10) | W | 17 | 16 |
| Oct. 14 | vs | *Maryland (3-7-1) | L | 7 | 27 |
| Oct. 21 | at | *Virginia (10-3) | L | 28 | 47 |
| Oct. 28 | at | *Clemson (10-2) | L | 10 | 44 |
| Nov. 4 | vs | *Duke (8-4) | L | 35 | 52 |
| Nov. 11 | vs | Tulsa (6-6) | W | 29 | 17 |
| Nov. 18 | at | *Georgia Tech (7-4) | L | 14 | 43 |
| | 2-8-1 | | 194 | 319 |
| 1988-Wake Forest (ACC) |
| Sep. 3 | at | Villanova ( ) | W | 31 | 11 |
| Sep. 10 | vs | Illinois State ( ) | W | 35 | 0 |
| Sep. 17 | at | *North Carolina State (8-3-1) | L | 6 | 14 |
| Sep. 24 | at | Michigan (9-2-1) | L | 9 | 19 |
| Oct. 8 | vs | *North Carolina (1-10) | W | 42 | 24 |
| Oct. 15 | at | *Maryland (5-6) | W | 27 | 24 |
| Oct. 22 | vs | *Virginia (7-4) | L | 14 | 34 |
| Oct. 29 | vs | *Clemson (10-2) | L | 21 | 38 |
| Nov. 5 | at | *Duke (7-3-1) | W | 35 | 16 |
| Nov. 12 | vs | *Georgia Tech (3-8) | W | 28 | 24 |
| Nov. 19 | vs | Appalachian State ( ) | T | 34 | 34 |
| | 6-4-1 | | 282 | 238 |
| 1987-Wake Forest (ACC) |
| Sep. 12 | vs | Richmond ( ) | W | 24 | 0 |
| Sep. 19 | vs | *North Carolina State (4-7) | W | 21 | 3 |
| Sep. 26 | vs | Appalachian State ( ) | W | 16 | 12 |
| Oct. 3 | at | Army (5-6) | W | 17 | 13 |
| Oct. 10 | at | *North Carolina (5-6) | W | 22 | 14 |
| Oct. 17 | vs | *Maryland (4-7) | L | 0 | 14 |
| Oct. 24 | at | *Virginia (8-4) | L | 21 | 35 |
| Oct. 31 | at | *Clemson (10-2) | L | 17 | 31 |
| Nov. 7 | vs | *Duke (5-6) | W | 30 | 27 |
| Nov. 14 | vs | South Carolina (8-4) | L | 0 | 30 |
| Nov. 21 | at | *Georgia Tech (2-9) | W | 33 | 6 |
| | 7-4-0 | | 201 | 185 |
| 1986-Wake Forest (ACC) |
| Sep. 6 | vs | Appalachian State ( ) | W | 21 | 13 |
| Sep. 13 | vs | Boston University ( ) | W | 31 | 0 |
| Sep. 20 | at | *North Carolina State (8-3-1) | L | 38 | 42 |
| Sep. 27 | at | Army (6-5) | W | 49 | 14 |
| Oct. 4 | vs | *Virginia (3-8) | L | 28 | 30 |
| Oct. 11 | vs | *North Carolina (7-4-1) | L | 30 | 40 |
| Oct. 18 | at | *Maryland (5-5-1) | W | 27 | 21 |
| Nov. 1 | vs | *Clemson (8-2-2) | L | 20 | 28 |
| Nov. 8 | at | *Duke (4-7) | L | 36 | 38 |
| Nov. 15 | at | South Carolina (3-6-2) | L | 21 | 48 |
| Nov. 22 | vs | *Georgia Tech (5-5-1) | W | 24 | 21 |
| | 5-6-0 | | 325 | 295 |
| 1985-Wake Forest (ACC) |
| Sep. 7 | vs | William & Mary ( ) | W | 30 | 23 |
| Sep. 14 | at | Boston University ( ) | W | 30 | 0 |
| Sep. 21 | vs | *North Carolina State (3-8) | L | 17 | 20 |
| Sep. 28 | vs | Appalachian State ( ) | W | 24 | 21 |
| Oct. 5 | at | Tennessee (9-1-2) | L | 29 | 31 |
| Oct. 12 | at | *North Carolina (5-6) | L | 14 | 34 |
| Oct. 19 | vs | *Maryland (9-3) | L | 3 | 26 |
| Oct. 26 | vs | *Virginia (6-5) | L | 18 | 20 |
| Nov. 2 | at | *Clemson (6-6) | L | 10 | 26 |
| Nov. 9 | vs | *Duke (4-7) | W | 27 | 7 |
| Nov. 16 | at | *Georgia Tech (9-2-1) | L | 10 | 41 |
| | 4-7-0 | | 212 | 249 |
| 1984-Wake Forest (ACC) |
| Sep. 8 | vs | Virginia Tech (8-4) | L | 20 | 21 |
| Sep. 15 | vs | Appalachian State ( ) | W | 17 | 13 |
| Sep. 22 | at | *North Carolina State (3-8) | W | 24 | 15 |
| Sep. 29 | at | *Maryland (9-3) | L | 17 | 38 |
| Oct. 6 | at | Richmond ( ) | W | 29 | 16 |
| Oct. 13 | vs | *North Carolina (5-5-1) | W | 14 | 3 |
| Oct. 20 | at | *Virginia (8-2-2) | L | 9 | 28 |
| Oct. 27 | vs | William & Mary ( ) | W | 34 | 21 |
| Nov. 3 | at | *Clemson (7-4) | L | 14 | 37 |
| Nov. 10 | at | *Duke (2-9) | W | 20 | 16 |
| Nov. 17 | vs | *Georgia Tech (6-4-1) | L | 7 | 24 |
| | 6-5-0 | | 205 | 232 |
| 1983-Wake Forest (ACC) |
| Sep. 3 | vs | Appalachian State ( ) | L | 25 | 27 |
| Sep. 10 | at | Virginia Tech (9-2) | W | 13 | 6 |
| Sep. 17 | vs | Western Carolina ( ) | W | 21 | 0 |
| Sep. 24 | at | Richmond (3-8) | W | 31 | 6 |
| Oct. 1 | vs | *North Carolina State (3-8) | L | 15 | 38 |
| Oct. 8 | at | *North Carolina (8-4) | L | 10 | 30 |
| Oct. 15 | vs | *Maryland (8-4) | L | 33 | 36 |
| Oct. 22 | vs | *Virginia (6-5) | W | 38 | 34 |
| Oct. 29 | at | *Clemson (9-1-1) | L | 17 | 24 |
| Nov. 5 | vs | *Duke (3-8) | L | 21 | 31 |
| Nov. 19 | at | *Georgia Tech (3-8) | L | 33 | 49 |
| | 4-7-0 | | 257 | 281 |
| 1982-Wake Forest (ACC) |
| Sep. 4 | vs | Western Carolina ( ) | W | 31 | 10 |
| Sep. 11 | at | Auburn (9-3) | L | 10 | 28 |
| Sep. 18 | at | *North Carolina State (6-5) | L | 0 | 30 |
| Sep. 25 | vs | Appalachian State ( ) | W | 31 | 22 |
| Oct. 2 | at | Virginia Tech (7-4) | W | 13 | 10 |
| Oct. 9 | vs | *North Carolina (8-4) | L | 7 | 24 |
| Oct. 16 | at | *Maryland (8-4) | L | 31 | 52 |
| Oct. 23 | at | *Virginia (2-9) | L | 27 | 34 |
| Nov. 6 | at | *Duke (6-5) | L | 26 | 46 |
| Nov. 13 | vs | Georgia Tech (6-5) | L | 7 | 45 |
| Nov. 27 | vs | *Clemson (9-1-1) | L | 17 | 21 | at Tokyo, Japan | Mirage Bowl |
| | 3-8-0 | | 200 | 322 |
| 1981-Wake Forest (ACC) |
| Sep. 5 | vs | South Carolina (6-6) | L | 6 | 23 |
| Sep. 12 | vs | *North Carolina State (4-7) | L | 23 | 28 |
| Sep. 19 | at | Auburn (5-6) | W | 24 | 21 |
| Sep. 26 | at | Virginia Tech (7-4) | L | 14 | 30 |
| Oct. 3 | vs | Appalachian State (3-7-1) | W | 15 | 14 |
| Oct. 10 | at | *North Carolina (10-2) | L | 10 | 48 |
| Oct. 17 | vs | *Maryland (4-6-1) | L | 33 | 45 |
| Oct. 24 | at | *Virginia (1-10) | W | 24 | 21 |
| Oct. 31 | at | *Clemson (12-0) | L | 24 | 82 |
| Nov. 7 | vs | *Duke (6-5) | L | 10 | 31 |
| Nov. 14 | at | Richmond (4-7) | W | 34 | 22 |
| | 4-7-0 | | 217 | 365 |
| 1980-Wake Forest (ACC) |
| Sep. 6 | vs | Virginia Tech (8-4) | L | 7 | 16 |
| Sep. 20 | vs | Citadel (7-4) | W | 24 | 7 |
| Sep. 27 | at | *North Carolina State (6-5) | W | 27 | 7 |
| Oct. 4 | at | William & Mary (2-9) | W | 27 | 7 |
| Oct. 11 | vs | *North Carolina (11-1) | L | 9 | 27 |
| Oct. 18 | at | *Maryland (8-4) | L | 10 | 11 |
| Oct. 25 | vs | *Virginia (4-7) | L | 21 | 24 |
| Nov. 1 | vs | *Clemson (6-5) | L | 33 | 35 |
| Nov. 8 | at | *Duke (2-9) | W | 27 | 24 |
| Nov. 15 | at | South Carolina (8-4) | L | 38 | 39 |
| Nov. 22 | vs | Appalachian State (6-4-1) | W | 28 | 16 |
| | 5-6-0 | | 251 | 213 |
| 1979-Wake Forest (ACC) |
| Sep. 8 | vs | Appalachian State (3-8) | W | 30 | 23 |
| Sep. 15 | at | Georgia (6-5) | W | 22 | 21 |
| Sep. 22 | vs | East Carolina (7-3-1) | W | 23 | 20 |
| Sep. 29 | at | *North Carolina State (7-4) | L | 14 | 17 |
| Oct. 6 | at | Virginia Tech (5-6) | W | 19 | 14 |
| Oct. 13 | at | *North Carolina (8-3-1) | W | 24 | 19 |
| Oct. 20 | vs | *Maryland (7-4) | W | 25 | 17 |
| Oct. 27 | vs | Auburn (8-3) | W | 42 | 38 |
| Nov. 3 | at | *Clemson (8-4) | L | 0 | 31 |
| Nov. 10 | vs | *Duke (2-8-1) | W | 17 | 14 |
| Nov. 17 | at | South Carolina (8-4) | L | 14 | 35 |
| Dec. 22 | vs | Louisiana State (7-5) | L | 10 | 34 | at Orlando, FL | Tangerine Bowl |
| | 8-4-0 | | 240 | 283 |
| 1978-Wake Forest (ACC) |
| Sep. 9 | vs | *Virginia (2-9) | W | 14 | 0 |
| Sep. 16 | vs | Virginia Tech (4-7) | L | 6 | 28 |
| Sep. 23 | at | Louisiana State (8-4) | L | 11 | 13 |
| Sep. 30 | vs | *North Carolina State (9-3) | L | 10 | 34 |
| Oct. 7 | at | Purdue (9-2-1) | L | 7 | 14 |
| Oct. 14 | vs | *North Carolina (5-6) | L | 29 | 34 |
| Oct. 21 | at | *Maryland (9-3) | L | 0 | 39 |
| Oct. 28 | at | Auburn (6-4-1) | L | 7 | 21 |
| Nov. 4 | vs | *Clemson (11-1) | L | 6 | 51 |
| Nov. 11 | at | *Duke (4-7) | L | 0 | 3 |
| Nov. 18 | at | South Carolina (5-5-1) | L | 14 | 37 |
| | 1-10-0 | | 104 | 274 |
| 1977-Wake Forest (ACC) |
| Sep. 10 | vs | Furman (4-5-2) | W | 24 | 13 |
| Sep. 17 | vs | Vanderbilt (2-9) | L | 0 | 3 |
| Sep. 24 | at | *North Carolina State (8-4) | L | 14 | 41 |
| Oct. 1 | at | Purdue (5-6) | L | 17 | 26 |
| Oct. 8 | at | *North Carolina (8-3-1) | L | 3 | 24 |
| Oct. 15 | vs | *Maryland (8-4) | L | 7 | 35 |
| Oct. 22 | at | *Virginia (1-9-1) | L | 10 | 12 |
| Oct. 29 | at | *Clemson (8-3-1) | L | 0 | 26 |
| Nov. 5 | vs | *Duke (5-6) | L | 14 | 38 |
| Nov. 12 | vs | South Carolina (5-7) | L | 14 | 24 |
| Nov. 19 | at | Virginia Tech (3-7-1) | L | 10 | 28 |
| | 1-10-0 | | 113 | 270 |
| 1976-Wake Forest (ACC) |
| Sep. 4 | vs | Virginia Tech (6-5) | L | 6 | 23 |
| Sep. 11 | vs | *North Carolina State (3-7-1) | W | 20 | 18 |
| Sep. 18 | at | Vanderbilt (2-9) | L | 24 | 27 |
| Sep. 25 | at | Kansas State (1-10) | W | 13 | 0 |
| Oct. 2 | at | Michigan (10-2) | L | 0 | 31 |
| Oct. 9 | vs | *Clemson (3-6-2) | W | 20 | 14 |
| Oct. 16 | at | *Maryland (11-1) | L | 15 | 17 |
| Oct. 23 | vs | *Virginia (2-9) | L | 17 | 18 |
| Oct. 30 | vs | *North Carolina (9-3) | L | 14 | 34 |
| Nov. 6 | at | *Duke (5-5-1) | W | 38 | 17 |
| Nov. 13 | at | South Carolina (6-5) | W | 10 | 7 |
| | 5-6-0 | | 177 | 206 |
| 1975-Wake Forest (ACC) |
| Sep. 6 | vs | Southern Methodist (4-7) | L | 7 | 14 |
| Sep. 13 | at | *North Carolina State (7-4-1) | W | 30 | 22 |
| Sep. 20 | vs | Appalachian State (8-3) | L | 17 | 19 |
| Sep. 27 | vs | Kansas State (3-8) | L | 16 | 17 |
| Oct. 11 | at | *Clemson (2-9) | L | 14 | 16 |
| Oct. 18 | vs | *Maryland (9-2-1) | L | 0 | 27 |
| Oct. 25 | at | *Virginia (1-10) | W | 66 | 21 |
| Nov. 1 | at | *North Carolina (3-7-1) | W | 21 | 9 |
| Nov. 8 | vs | *Duke (4-5-2) | L | 14 | 42 |
| Nov. 15 | at | South Carolina (7-5) | L | 26 | 37 |
| Nov. 22 | at | Virginia Tech (8-3) | L | 10 | 40 |
| | 3-8-0 | | 221 | 264 |
| 1974-Wake Forest (ACC) |
| Sep. 7 | vs | *North Carolina State (9-2-1) | L | 15 | 33 |
| Sep. 14 | vs | William & Mary (4-7) | L | 6 | 17 |
| Sep. 21 | vs | *North Carolina (7-5) | L | 0 | 31 |
| Oct. 5 | at | Oklahoma (11-0) | L | 0 | 63 |
| Oct. 12 | at | Penn State (10-2) | L | 0 | 55 |
| Oct. 19 | at | *Maryland (8-4) | L | 0 | 47 |
| Oct. 26 | vs | *Virginia (4-7) | L | 0 | 14 |
| Nov. 2 | vs | *Clemson (7-4) | L | 9 | 21 |
| Nov. 9 | at | *Duke (6-5) | L | 7 | 23 |
| Nov. 16 | at | South Carolina (4-7) | L | 21 | 34 |
| Nov. 23 | vs | Furman (5-6) | W | 16 | 10 |
| | 1-10-0 | | 74 | 348 |
| 1973-Wake Forest (ACC) |
| Sep. 15 | vs | Florida State (0-11) | W | 9 | 7 |
| Sep. 22 | vs | William & Mary (6-5) | L | 14 | 15 |
| Sep. 29 | at | Richmond (8-2) | L | 0 | 41 |
| Oct. 6 | at | Texas (8-3) | L | 0 | 41 |
| Oct. 13 | vs | South Carolina (7-4) | L | 12 | 28 |
| Oct. 20 | vs | *Maryland (8-4) | L | 0 | 37 |
| Oct. 27 | at | *Virginia (4-7) | L | 10 | 21 |
| Nov. 3 | at | *Clemson (5-6) | L | 8 | 35 |
| Nov. 10 | vs | *Duke (2-8-1) | T | 7 | 7 |
| Nov. 17 | at | *North Carolina (4-7) | L | 0 | 42 |
| Nov. 24 | at | *North Carolina State (9-3) | L | 13 | 52 |
| | 1-9-1 | | 73 | 326 |
| 1972-Wake Forest (ACC) |
| Sep. 9 | vs | Davidson (3-7-1) | W | 26 | 20 |
| Sep. 16 | vs | Southern Methodist (7-4) | L | 10 | 56 | at Irving, TX |
| Sep. 23 | at | Tennessee (10-2) | L | 6 | 45 |
| Oct. 7 | at | *Maryland (5-5-1) | L | 0 | 23 |
| Oct. 14 | vs | *North Carolina State (8-3-1) | L | 13 | 42 |
| Oct. 21 | vs | *North Carolina (11-1) | L | 0 | 21 |
| Oct. 28 | vs | *Clemson (4-7) | L | 0 | 31 |
| Nov. 4 | at | South Carolina (4-7) | L | 3 | 35 |
| Nov. 11 | at | *Duke (5-6) | W | 9 | 7 |
| Nov. 18 | vs | *Virginia (4-7) | L | 12 | 15 |
| Nov. 25 | vs | Virginia Tech (6-4-1) | L | 9 | 44 |
| | 2-9-0 | | 88 | 339 |
| 1971-Wake Forest (ACC) |
| Sep. 11 | vs | Davidson (1-9) | W | 27 | 7 |
| Sep. 18 | at | Virginia Tech (4-7) | W | 20 | 9 |
| Sep. 25 | vs | Miami (Florida) (4-7) | L | 10 | 29 |
| Oct. 2 | at | *Maryland (2-9) | W | 18 | 14 |
| Oct. 9 | at | *North Carolina State (3-8) | L | 14 | 21 |
| Oct. 16 | vs | Tulsa (4-7) | W | 51 | 21 |
| Oct. 23 | at | *North Carolina (9-3) | L | 3 | 7 |
| Oct. 30 | at | *Clemson (5-6) | L | 9 | 10 |
| Nov. 6 | vs | William & Mary (5-6) | W | 36 | 29 |
| Nov. 13 | vs | *Duke (6-5) | W | 23 | 7 |
| Nov. 20 | at | *South Carolina (6-5) | L | 7 | 24 |
| | 6-5-0 | | 218 | 178 |
| 1970-Wake Forest (ACC) |
| Sep. 12 | at | Nebraska (11-0-1) | L | 12 | 36 |
| Sep. 19 | at | *South Carolina (4-6-1) | L | 7 | 43 |
| Sep. 26 | at | Florida State (7-4) | L | 14 | 19 |
| Oct. 3 | at | *Virginia (5-6) | W | 27 | 7 |
| Oct. 10 | vs | Virginia Tech (5-6) | W | 28 | 9 |
| Oct. 17 | vs | *Clemson (3-8) | W | 36 | 20 |
| Oct. 24 | vs | *North Carolina (8-4) | W | 14 | 13 |
| Oct. 31 | vs | Tennessee (11-1) | L | 7 | 41 | at Memphis, TN |
| Nov. 7 | at | *Duke (6-5) | W | 28 | 14 |
| Nov. 14 | vs | *North Carolina State (3-7-1) | W | 16 | 13 |
| Nov. 21 | at | Houston (8-3) | L | 2 | 26 |
| | 6-5-0 | | 191 | 241 |
| 1969-Wake Forest (ACC) |
| Sep. 13 | at | *North Carolina State (3-6-1) | W | 22 | 21 |
| Sep. 20 | at | Auburn (8-3) | L | 0 | 57 |
| Sep. 27 | vs | Virginia Tech (4-5-1) | W | 16 | 10 |
| Oct. 4 | vs | *Maryland (3-7) | L | 14 | 19 |
| Oct. 11 | vs | *Duke (3-6-1) | L | 20 | 27 |
| Oct. 18 | at | *Clemson (4-6) | L | 14 | 28 |
| Oct. 25 | at | *North Carolina (5-5) | L | 3 | 23 |
| Nov. 8 | at | *Virginia (3-7) | W | 23 | 21 |
| Nov. 15 | vs | *South Carolina (7-4) | L | 6 | 24 |
| Nov. 21 | at | Miami (Florida) (4-6) | L | 7 | 49 |
| | 3-7-0 | | 125 | 279 |
| 1968-Wake Forest (ACC) |
| Sep. 14 | vs | *North Carolina State (6-4) | L | 6 | 10 |
| Sep. 21 | vs | *Clemson (4-5-1) | T | 20 | 20 |
| Oct. 5 | at | Minnesota (6-4) | L | 19 | 24 |
| Oct. 12 | at | Virginia Tech (7-4) | L | 6 | 7 |
| Oct. 19 | at | Purdue (8-2) | L | 27 | 28 |
| Oct. 26 | vs | *North Carolina (3-7) | W | 48 | 31 |
| Nov. 2 | vs | *Maryland (2-8) | W | 38 | 14 |
| Nov. 9 | vs | *South Carolina (4-6) | L | 21 | 34 |
| Nov. 16 | at | *Duke (4-6) | L | 3 | 18 |
| Nov. 23 | at | Florida State (8-3) | L | 24 | 42 |
| | 2-7-1 | | 212 | 228 |
| 1967-Wake Forest (ACC) |
| Sep. 16 | vs | *Duke (4-6) | L | 13 | 31 | at Raleigh, NC |
| Sep. 23 | at | *Clemson (6-4) | L | 6 | 23 |
| Sep. 29 | at | Houston (7-3) | L | 6 | 50 |
| Oct. 7 | vs | *Virginia (5-5) | L | 12 | 14 |
| Oct. 14 | at | Memphis (6-3) | L | 10 | 42 |
| Oct. 21 | at | *North Carolina State (9-2) | L | 7 | 24 |
| Oct. 28 | at | *North Carolina (2-8) | W | 20 | 10 |
| Nov. 4 | vs | *South Carolina (5-5) | W | 35 | 21 |
| Nov. 11 | at | Tulsa (7-3) | W | 31 | 24 |
| Nov. 17 | vs | *Maryland (0-9) | W | 35 | 17 |
| | 4-6-0 | | 175 | 256 |
| 1966-Wake Forest (ACC) |
| Sep. 17 | at | *Virginia (4-6) | L | 10 | 24 |
| Sep. 24 | at | *Maryland (4-6) | L | 7 | 34 |
| Oct. 1 | vs | *North Carolina State (5-5) | L | 12 | 15 |
| Oct. 8 | at | Auburn (4-6) | L | 6 | 14 |
| Oct. 15 | at | *South Carolina (1-9) | W | 10 | 6 |
| Oct. 22 | at | *North Carolina (2-8) | W | 3 | 0 |
| Oct. 29 | vs | *Clemson (6-4) | L | 21 | 23 |
| Nov. 5 | vs | Virginia Tech (8-2-1) | L | 0 | 11 |
| Nov. 12 | vs | Memphis (7-2) | W | 21 | 7 |
| Nov. 19 | at | Florida State (6-5) | L | 0 | 28 |
| | 3-7-0 | | 90 | 162 |
| 1965-Wake Forest (ACC) |
| Sep. 18 | vs | Virginia Tech (7-3) | L | 3 | 12 | at Roanoke, VA |
| Sep. 25 | at | *North Carolina State (6-4) | L | 11 | 13 |
| Oct. 2 | vs | Vanderbilt (2-7-1) | W | 7 | 0 |
| Oct. 9 | vs | *Maryland (4-6) | L | 7 | 10 |
| Oct. 16 | at | *South Carolina (5-5) | L | 7 | 38 |
| Oct. 23 | vs | *North Carolina (4-6) | W | 12 | 10 |
| Oct. 30 | at | *Clemson (5-5) | L | 13 | 26 |
| Nov. 6 | at | Florida State (4-5-1) | L | 0 | 35 |
| Nov. 13 | at | *Duke (6-4) | L | 7 | 40 |
| Nov. 20 | at | Memphis (5-5) | W | 21 | 20 |
| | 3-7-0 | | 88 | 204 |
| 1964-Wake Forest (ACC) |
| Sep. 19 | at | *Virginia (5-5) | W | 31 | 21 |
| Sep. 26 | vs | Virginia Tech (6-4) | W | 38 | 21 | at Roanoke, VA |
| Oct. 3 | at | *North Carolina (5-5) | L | 0 | 23 |
| Oct. 10 | at | Vanderbilt (3-6-1) | L | 6 | 9 |
| Oct. 17 | vs | *Clemson (3-7) | L | 2 | 21 |
| Oct. 24 | at | *Maryland (5-5) | W | 21 | 17 |
| Oct. 31 | at | Memphis (5-4) | L | 14 | 23 |
| Nov. 7 | vs | *Duke (4-5-1) | W | 20 | 7 |
| Nov. 14 | at | *South Carolina (3-5-2) | L | 13 | 23 |
| Nov. 20 | vs | *North Carolina State (5-5) | W | 27 | 13 |
| | 5-5-0 | | 172 | 178 |
| 1963-Wake Forest (ACC) |
| Sep. 21 | at | East Carolina ( ) | L | 10 | 20 |
| Sep. 28 | vs | Virginia Tech (8-2) | L | 0 | 27 |
| Oct. 5 | vs | *North Carolina (9-2) | L | 0 | 21 |
| Oct. 12 | at | Florida State (4-5-1) | L | 0 | 35 |
| Oct. 19 | at | Army (7-3) | L | 0 | 47 |
| Oct. 26 | vs | *Maryland (3-7) | L | 0 | 32 |
| Nov. 2 | at | *Clemson (5-4-1) | L | 0 | 36 |
| Nov. 9 | at | *Duke (5-4-1) | L | 7 | 39 |
| Nov. 16 | vs | *South Carolina (1-8-1) | W | 20 | 19 |
| Nov. 22 | at | *North Carolina State (8-3) | L | 0 | 42 |
| | 1-9-0 | | 37 | 318 |
| 1962-Wake Forest (ACC) |
| Sep. 22 | at | Army (6-4) | L | 14 | 40 |
| Sep. 29 | vs | *Maryland (6-4) | L | 2 | 13 |
| Oct. 6 | vs | *Clemson (6-4) | L | 7 | 24 |
| Oct. 13 | at | *South Carolina (4-5-1) | L | 6 | 27 |
| Oct. 20 | at | *Virginia (5-5) | L | 12 | 14 |
| Oct. 27 | at | *North Carolina (3-7) | L | 14 | 23 |
| Nov. 3 | at | Tennessee (4-6) | L | 0 | 23 |
| Nov. 10 | at | Virginia Tech (5-5) | L | 8 | 37 |
| Nov. 17 | vs | *Duke (8-2) | L | 0 | 50 |
| Nov. 22 | vs | *North Carolina State (3-6-1) | L | 3 | 27 |
| | 0-10-0 | | 66 | 278 |
| 1961-Wake Forest (ACC) |
| Sep. 23 | at | Baylor (6-5) | L | 0 | 31 |
| Sep. 30 | vs | *South Carolina (4-6) | L | 7 | 10 |
| Oct. 7 | at | *Duke (7-3) | L | 3 | 23 |
| Oct. 14 | at | *Clemson (5-5) | W | 17 | 13 |
| Oct. 21 | at | *North Carolina State (4-6) | L | 0 | 7 |
| Oct. 28 | vs | *Virginia (4-6) | W | 21 | 15 |
| Nov. 4 | at | Auburn (6-4) | L | 7 | 21 |
| Nov. 11 | vs | Virginia Tech (4-5) | W | 24 | 15 |
| Nov. 18 | at | *Maryland (7-3) | L | 7 | 10 |
| Nov. 25 | vs | *North Carolina (5-5) | W | 17 | 14 |
| | 4-6-0 | | 103 | 159 |
| 1960-Wake Forest (ACC) |
| Sep. 24 | vs | *Clemson (6-4) | L | 7 | 28 |
| Oct. 1 | at | Florida State (3-6-1) | L | 6 | 14 |
| Oct. 8 | at | Virginia Tech (6-4) | L | 13 | 22 |
| Oct. 15 | at | *North Carolina (3-7) | W | 13 | 12 |
| Oct. 22 | vs | *Maryland (6-4) | L | 13 | 14 |
| Oct. 29 | at | *Virginia (0-10) | W | 28 | 20 |
| Nov. 5 | vs | *North Carolina State (6-3-1) | L | 12 | 14 |
| Nov. 12 | vs | *Duke (8-3) | L | 7 | 34 |
| Nov. 19 | at | Louisiana State (5-4-1) | L | 0 | 16 |
| Nov. 26 | at | *South Carolina (3-6-1) | L | 20 | 41 |
| | 2-8-0 | | 119 | 215 |
| 1959-Wake Forest (ACC) |
| Sep. 19 | at | Florida State (4-6) | W | 22 | 20 |
| Sep. 26 | vs | Virginia Tech (6-4) | W | 27 | 18 |
| Oct. 3 | at | Tulane (3-6-1) | L | 0 | 6 |
| Oct. 10 | at | *Maryland (5-5) | W | 10 | 7 |
| Oct. 17 | at | *North Carolina State (1-9) | W | 17 | 14 |
| Oct. 24 | vs | *North Carolina (5-5) | L | 19 | 21 |
| Oct. 31 | vs | *Virginia (0-10) | W | 34 | 12 |
| Nov. 14 | at | *Duke (4-6) | L | 15 | 27 |
| Nov. 21 | at | *Clemson (9-2) | L | 31 | 33 |
| Nov. 28 | vs | *South Carolina (6-4) | W | 43 | 20 | at Charlotte, NC |
| | 6-4-0 | | 218 | 178 |
| 1958-Wake Forest (ACC) |
| Sep. 20 | vs | *Maryland (4-6) | W | 34 | 0 |
| Sep. 27 | vs | Virginia Tech (5-4-1) | W | 13 | 6 | at Norfolk, VA |
| Oct. 4 | at | Florida State (7-4) | L | 24 | 27 |
| Oct. 11 | vs | *North Carolina State (2-7-1) | W | 13 | 7 |
| Oct. 18 | at | Villanova (6-4) | L | 7 | 9 |
| Oct. 25 | at | *North Carolina (6-4) | L | 7 | 26 |
| Nov. 1 | at | *Clemson (8-3) | L | 12 | 14 |
| Nov. 15 | vs | *Duke (5-5) | L | 0 | 29 |
| Nov. 22 | at | Auburn (9-0-1) | L | 7 | 21 |
| Nov. 27 | at | *South Carolina (7-3) | L | 7 | 24 |
| | 3-7-0 | | 124 | 163 |
| 1957-Wake Forest (ACC) |
| Sep. 28 | at | Florida (6-2-1) | L | 0 | 27 |
| Oct. 5 | vs | *Virginia (3-6-1) | L | 20 | 28 |
| Oct. 12 | at | *Maryland (5-5) | L | 0 | 27 |
| Oct. 19 | at | *Duke (6-3-2) | L | 7 | 34 |
| Oct. 26 | vs | *North Carolina (6-4) | L | 7 | 14 |
| Nov. 2 | at | *North Carolina State (7-1-2) | L | 0 | 19 |
| Nov. 9 | vs | Virginia Tech (4-6) | L | 3 | 10 |
| Nov. 16 | vs | West Virginia (7-2-1) | L | 14 | 27 |
| Nov. 23 | at | *Clemson (7-3) | L | 6 | 13 |
| Nov. 30 | vs | *South Carolina (5-5) | L | 7 | 26 |
| | 0-10-0 | | 64 | 225 |
| 1956-Wake Forest (ACC) |
| Sep. 22 | at | William & Mary (0-9-1) | W | 39 | 0 |
| Sep. 29 | vs | *Maryland (2-7-1) | L | 0 | 6 |
| Oct. 6 | at | *Virginia (3-7) | L | 6 | 7 |
| Oct. 13 | vs | *Clemson (7-2-2) | L | 0 | 17 |
| Oct. 20 | at | Florida State (5-4-1) | T | 14 | 14 |
| Oct. 27 | at | *North Carolina (2-7-1) | T | 6 | 6 |
| Nov. 3 | vs | *North Carolina State (3-7) | W | 13 | 0 |
| Nov. 10 | at | Virginia Tech (7-2-1) | T | 13 | 13 |
| Nov. 17 | vs | *Duke (5-4-1) | L | 0 | 26 |
| Nov. 22 | vs | *South Carolina (7-3) | L | 0 | 13 | at Charlotte, NC |
| | 2-5-3 | | 91 | 102 |
| 1955-Wake Forest (ACC) |
| Sep. 17 | vs | Virginia Tech (6-3-1) | W | 13 | 0 |
| Sep. 24 | vs | *South Carolina (3-6) | W | 34 | 19 | at Winston-Salem, NC |
| Oct. 1 | at | West Virginia (8-2) | L | 0 | 46 |
| Oct. 8 | at | *Maryland (10-1) | L | 7 | 28 |
| Oct. 15 | at | *North Carolina State (4-5-1) | T | 13 | 13 |
| Oct. 22 | vs | *North Carolina (3-7) | W | 25 | 0 |
| Oct. 29 | at | *Clemson (7-3) | L | 13 | 19 |
| Nov. 5 | vs | William & Mary (1-7-1) | W | 13 | 7 |
| Nov. 12 | at | *Virginia (1-9) | W | 13 | 7 |
| Nov. 19 | at | *Duke (7-2-1) | L | 0 | 14 |
| | 5-4-1 | | 131 | 153 |
| 1954-Wake Forest (ACC) |
| Sep. 18 | vs | George Washington (1-7-1) | W | 14 | 0 |
| Sep. 25 | vs | Virginia Tech (8-0-1) | L | 0 | 32 | at Richmond, VA |
| Oct. 2 | vs | *North Carolina State (2-8) | W | 26 | 0 |
| Oct. 9 | vs | *Maryland (7-2-1) | T | 13 | 13 | at Winston-Salem, NC |
| Oct. 23 | at | *North Carolina (4-5-1) | L | 7 | 14 |
| Oct. 30 | vs | *Clemson (5-5) | L | 20 | 32 | at Charlotte, NC |
| Nov. 6 | at | Richmond (5-4) | L | 0 | 13 |
| Nov. 13 | vs | *Duke (8-2-1) | L | 21 | 28 |
| Nov. 20 | at | William & Mary (4-4-2) | L | 9 | 13 |
| Nov. 27 | at | *South Carolina (6-4) | L | 19 | 20 |
| | 2-7-1 | | 129 | 165 |
| 1953-Wake Forest (ACC) |
| Sep. 19 | vs | William & Mary (5-4-1) | L | 14 | 16 | at Richmond, VA |
| Sep. 26 | at | *Duke (7-2-1) | L | 0 | 19 |
| Oct. 3 | vs | Villanova (4-6) | W | 18 | 12 | at Winston-Salem, NC |
| Oct. 10 | vs | *North Carolina (4-6) | L | 13 | 18 |
| Oct. 17 | at | *North Carolina State (1-9) | W | 20 | 7 |
| Oct. 24 | at | Richmond (5-3-1) | T | 13 | 13 |
| Oct. 31 | at | *Clemson (3-5-1) | L | 0 | 18 |
| Nov. 7 | at | Boston College (5-3-1) | L | 7 | 20 |
| Nov. 21 | vs | Furman (7-2) | L | 10 | 21 |
| Nov. 26 | vs | *South Carolina (7-3) | W | 19 | 13 | at Charlotte, NC |
| | 3-6-1 | | 114 | 157 |
| 1952-Wake Forest (Southern) |
| Sep. 20 | at | Baylor (4-4-2) | L | 14 | 17 |
| Sep. 27 | at | *William & Mary (4-5) | W | 28 | 21 |
| Oct. 4 | vs | Boston College (4-4-1) | T | 7 | 7 | at Winston-Salem, NC |
| Oct. 11 | vs | Villanova (7-1-1) | L | 0 | 20 | at Philadelphia, PA |
| Oct. 18 | at | *North Carolina (2-6) | W | 9 | 7 |
| Nov. 1 | vs | *North Carolina State (3-7) | W | 21 | 6 |
| Nov. 8 | at | Texas Christian (4-4-2) | L | 9 | 27 |
| Nov. 15 | vs | *Duke (8-2) | L | 7 | 14 |
| Nov. 22 | at | *Furman (6-3-1) | W | 28 | 0 |
| Nov. 29 | vs | *South Carolina (5-5) | W | 39 | 14 | at Winston-Salem, NC |
| | 5-4-1 | | 162 | 133 |
| 1951-Wake Forest (Southern) |
| Sep. 21 | at | Boston College (3-6) | W | 20 | 6 |
| Sep. 29 | at | *North Carolina State (3-7) | W | 21 | 6 |
| Oct. 6 | vs | *Richmond (3-8) | W | 56 | 6 |
| Oct. 13 | vs | *William & Mary (7-3) | L | 6 | 7 | at Richmond, VA |
| Oct. 19 | at | *George Washington (2-6-1) | W | 27 | 13 |
| Oct. 27 | vs | *North Carolina (2-8) | W | 39 | 7 |
| Nov. 3 | at | *Clemson (7-3) | L | 6 | 21 |
| Nov. 10 | at | *Duke (5-4-1) | W | 19 | 13 |
| Nov. 17 | at | Baylor (8-2-1) | L | 0 | 42 |
| Nov. 24 | at | *South Carolina (5-4) | L | 6 | 21 |
| | 6-4-0 | | 200 | 142 |
| 1950-Wake Forest (Southern) |
| Sep. 22 | at | Boston College (0-9-1) | T | 7 | 7 |
| Sep. 30 | vs | *Richmond (2-8) | W | 43 | 0 |
| Oct. 7 | at | *William & Mary (4-7) | W | 47 | 0 |
| Oct. 14 | at | *North Carolina (3-5-2) | W | 13 | 7 |
| Oct. 21 | vs | *George Washington (5-4) | W | 13 | 7 |
| Oct. 28 | vs | *Clemson (9-0-1) | L | 12 | 13 |
| Nov. 11 | at | *Duke (7-3) | W | 13 | 7 |
| Nov. 18 | vs | *North Carolina State (5-4-1) | T | 6 | 6 |
| Nov. 25 | at | *South Carolina (3-4-2) | W | 14 | 7 |
| | 6-1-2 | | 168 | 54 |
| 1949-Wake Forest (Southern) |
| Sep. 17 | vs | Duquesne (3-6) | W | 22 | 7 |
| Sep. 24 | at | Southern Methodist (5-4-1) | L | 7 | 13 |
| Sep. 30 | at | Boston College (4-4-1) | L | 7 | 13 |
| Oct. 8 | vs | Georgetown (5-5) | L | 6 | 12 |
| Oct. 15 | at | *North Carolina (7-4) | L | 14 | 28 |
| Oct. 22 | vs | *William & Mary (6-4) | W | 55 | 28 |
| Oct. 29 | at | *Clemson (4-4-2) | W | 35 | 21 |
| Nov. 5 | at | *Duke (6-3) | W | 27 | 7 |
| Nov. 12 | at | *North Carolina State (3-7) | L | 14 | 27 |
| Nov. 26 | at | *South Carolina (4-6) | L | 20 | 27 |
| | 4-6-0 | | 207 | 183 |
| 1948-Wake Forest (Southern) |
| Sep. 18 | at | *George Washington (4-6) | W | 27 | 13 |
| Sep. 24 | at | Boston College (5-2-2) | L | 9 | 26 |
| Oct. 2 | at | *William & Mary (7-2-2) | W | 21 | 12 |
| Oct. 9 | vs | *North Carolina (9-1-1) | L | 6 | 28 |
| Oct. 16 | at | Duquesne (2-7) | W | 41 | 15 |
| Oct. 30 | vs | *North Carolina State (3-6-1) | W | 34 | 13 |
| Nov. 6 | at | *Duke (4-3-2) | W | 27 | 20 |
| Nov. 13 | vs | *Clemson (11-0) | L | 14 | 21 | at Winston-Salem, NC |
| Nov. 25 | at | *South Carolina (3-5) | W | 38 | 0 |
| Jan. 1 | vs | Baylor (6-3-2) | L | 7 | 20 | at Birmingham, AL | Dixie Bowl |
| | 6-4-0 | | 224 | 168 |
| 1947-Wake Forest (Southern) |
| Sep. 27 | vs | Georgetown (3-4-1) | W | 6 | 0 |
| Oct. 4 | at | *Clemson (4-5) | W | 16 | 14 |
| Oct. 11 | at | *North Carolina (8-2) | W | 19 | 7 |
| Oct. 18 | at | *George Washington (1-7-1) | W | 39 | 7 |
| Oct. 25 | vs | *Duke (4-3-2) | L | 6 | 13 |
| Nov. 1 | at | *William & Mary (9-2) | L | 0 | 21 |
| Nov. 8 | at | Boston College (5-4) | W | 14 | 13 |
| Nov. 15 | at | *North Carolina State (5-3-1) | L | 0 | 20 |
| Nov. 21 | vs | Duquesne (2-8) | W | 33 | 0 | at Winston-Salem, NC |
| Nov. 27 | vs | *South Carolina (6-2-1) | L | 0 | 6 | at Charlotte, NC |
| | 6-4-0 | | 133 | 101 |
| 1946-Wake Forest (Southern) |
| Sep. 27 | at | Boston College (6-3) | W | 12 | 6 |
| Oct. 4 | at | Georgetown (5-3) | W | 19 | 6 |
| Oct. 12 | vs | *Clemson (4-5) | W | 19 | 7 |
| Oct. 19 | vs | *North Carolina State (8-3) | L | 6 | 14 |
| Oct. 26 | at | Tennessee (9-2) | W | 19 | 6 |
| Nov. 1 | at | Tennessee-Chattanooga (5-5) | W | 32 | 14 |
| Nov. 9 | at | *Duke (4-5) | L | 0 | 13 |
| Nov. 16 | at | *North Carolina (8-2-1) | L | 14 | 26 |
| Nov. 28 | vs | *South Carolina (5-3) | W | 35 | 0 | at Charlotte, NC |
| | 6-3-0 | | 156 | 92 |
| 1945-Wake Forest (Southern) |
| Sep. 29 | at | Tennessee (8-1) | L | 6 | 7 |
| Oct. 6 | at | Army (9-0) | L | 0 | 54 |
| Oct. 13 | vs | *Duke (6-2) | L | 19 | 26 |
| Oct. 20 | at | *North Carolina State (3-6) | W | 19 | 18 |
| Nov. 3 | vs | Presbyterian (1-6) | W | 53 | 0 |
| Nov. 17 | at | *North Carolina (5-5) | W | 14 | 13 |
| Nov. 22 | vs | *South Carolina (2-4-3) | T | 13 | 13 | at Charlotte, NC |
| Dec. 1 | at | *Clemson (6-3-1) | W | 13 | 6 |
| Jan. 1 | vs | *South Carolina (2-4-3) | W | 26 | 14 | at Jacksonville, FL | Gator Bowl |
| | 5-3-1 | | 163 | 151 |
| 1944-Wake Forest (Southern) |
| Sep. 23 | at | *North Carolina (1-7-1) | W | 7 | 0 |
| Sep. 29 | at | Georgia (7-3) | W | 14 | 7 |
| Oct. 7 | vs | *Maryland (1-7-1) | W | 39 | 0 |
| Oct. 14 | vs | *Virginia Military Institute (1-8) | W | 38 | 7 | at Greensboro, NC |
| Oct. 21 | at | *North Carolina State (7-2) | W | 21 | 7 |
| Oct. 27 | at | Miami (Florida) (1-7-1) | W | 27 | 0 |
| Nov. 4 | vs | *Clemson (4-5) | W | 13 | 7 |
| Nov. 11 | at | *Duke (6-4) | L | 0 | 34 |
| Nov. 23 | vs | *South Carolina (3-4-2) | W | 19 | 13 | at Charlotte, NC |
| | 8-1-0 | | 178 | 75 |
| 1943-Wake Forest (Southern) |
| Sep. 25 | at | Camp Davis ( ) | L | 20 | 24 |
| Oct. 2 | at | *Maryland (4-5) | L | 7 | 13 |
| Oct. 8 | at | Georgia (6-4) | L | 0 | 7 |
| Oct. 16 | at | *North Carolina State (3-6) | W | 54 | 6 |
| Oct. 23 | vs | *Virginia Military Institute (2-6) | W | 21 | 0 | at Lynchburg, VA |
| Oct. 30 | at | *Clemson (2-6) | W | 41 | 12 |
| Nov. 6 | vs | North Carolina Pre-Flight (2-4-1) | W | 20 | 12 |
| Nov. 13 | at | Greensboro Field ( ) | L | 0 | 14 |
| Nov. 25 | vs | *South Carolina (5-2) | L | 2 | 13 | at Charlotte, NC |
| | 4-5-0 | | 165 | 101 |
| 1942-Wake Forest (Southern) |
| Sep. 26 | at | *North Carolina (5-2-2) | L | 0 | 6 |
| Oct. 3 | vs | *Duke (5-4-1) | W | 20 | 7 |
| Oct. 10 | at | *Furman (3-6) | W | 14 | 6 |
| Oct. 17 | at | *North Carolina State (4-4-2) | T | 0 | 0 |
| Oct. 25 | at | Boston College (8-2) | L | 0 | 27 |
| Oct. 31 | vs | *Clemson (3-6-1) | W | 19 | 6 |
| Nov. 7 | vs | *Virginia Military Institute (3-5-1) | W | 28 | 0 | at Winston-Salem, NC |
| Nov. 13 | at | *George Washington (3-6) | W | 20 | 0 |
| Nov. 26 | vs | *South Carolina (1-7-1) | W | 33 | 14 | at Charlotte, NC |
| | 6-2-1 | | 134 | 66 |
| 1941-Wake Forest (Southern) |
| Sep. 20 | at | Camp Davis ( ) | W | 66 | 0 |
| Sep. 27 | at | *Duke (9-1) | L | 14 | 43 |
| Oct. 4 | at | *Furman (3-4-2) | W | 52 | 13 |
| Oct. 11 | at | *South Carolina (4-4-1) | T | 6 | 6 |
| Oct. 18 | at | *North Carolina State (4-5-2) | W | 7 | 0 |
| Oct. 25 | vs | *North Carolina (3-7) | W | 13 | 0 |
| Nov. 1 | at | Marshall ( ) | L | 6 | 16 |
| Nov. 8 | at | Boston College (7-3) | L | 6 | 26 |
| Nov. 15 | at | *Clemson (7-2) | L | 0 | 29 |
| Nov. 20 | at | *George Washington (1-7-1) | W | 42 | 0 |
| Nov. 29 | vs | Texas Tech (9-2) | L | 6 | 35 | at Charlotte, NC |
| | 5-5-1 | | 218 | 168 |
| 1940-Wake Forest (Southern) |
| Sep. 21 | vs | William Jewell ( ) | W | 79 | 0 |
| Sep. 28 | at | *North Carolina (6-4) | W | 12 | 0 |
| Oct. 5 | vs | *Furman (5-4) | W | 19 | 0 |
| Oct. 12 | at | *Clemson (6-2-1) | L | 0 | 39 |
| Oct. 19 | vs | Marshall ( ) | W | 31 | 19 |
| Oct. 26 | vs | *Duke (7-2) | L | 0 | 23 |
| Nov. 1 | at | George Washington (5-3-1) | W | 18 | 0 |
| Nov. 9 | at | *North Carolina State (3-6) | W | 20 | 14 |
| Nov. 16 | at | Texas Tech (9-1-1) | L | 7 | 12 |
| Nov. 28 | vs | *South Carolina (3-6) | W | 7 | 6 | at Charlotte, NC |
| | 7-3-0 | | 193 | 113 |
| 1939-Wake Forest (Southern) |
| Sep. 16 | vs | Elon ( ) | W | 34 | 0 | at Greensboro, NC |
| Sep. 23 | vs | *South Carolina (3-6-1) | W | 19 | 7 |
| Sep. 30 | at | *North Carolina (8-1-1) | L | 6 | 36 |
| Oct. 6 | at | Miami (Florida) (5-5) | W | 33 | 0 |
| Oct. 14 | at | *North Carolina State (2-8) | W | 32 | 0 |
| Oct. 21 | vs | McDaniel ( ) | W | 66 | 0 |
| Oct. 28 | at | *Duke (8-1) | L | 0 | 6 |
| Nov. 4 | at | Marshall ( ) | W | 14 | 13 |
| Nov. 11 | at | *Clemson (9-1) | L | 7 | 20 |
| Nov. 30 | vs | *Davidson (2-7) | W | 46 | 7 | at Charlotte, NC |
| | 7-3-0 | | 257 | 89 |
| 1938-Wake Forest (Southern) |
| Sep. 17 | vs | Randolph-Macon ( ) | W | 57 | 6 |
| Sep. 24 | at | *North Carolina (6-2-1) | L | 6 | 14 |
| Sep. 30 | vs | *Citadel (6-5) | W | 31 | 0 | at Charlotte, NC |
| Oct. 8 | at | *South Carolina (6-4-1) | W | 20 | 19 |
| Oct. 15 | at | *North Carolina State (3-7-1) | L | 7 | 19 |
| Oct. 22 | vs | *Duke (9-1) | L | 0 | 7 | at Winston-Salem, NC |
| Oct. 28 | vs | *Clemson (7-1-1) | L | 0 | 7 |
| Nov. 5 | at | *Virginia Military Institute (6-1-4) | T | 6 | 6 |
| Nov. 12 | vs | McDaniel ( ) | L | 13 | 20 |
| Nov. 24 | vs | *Davidson (4-6) | W | 21 | 0 | at Charlotte, NC |
| | 4-5-1 | | 161 | 98 |
| 1937-Wake Forest (Southern) |
| Sep. 25 | at | Tennessee (6-3-1) | L | 0 | 32 |
| Oct. 1 | at | George Washington (3-4-1) | L | 6 | 34 |
| Oct. 8 | vs | Erskine ( ) | W | 18 | 0 |
| Oct. 16 | vs | *North Carolina (7-1-1) | L | 0 | 28 |
| Oct. 23 | vs | *North Carolina State (5-3-1) | L | 0 | 20 |
| Oct. 30 | at | *Clemson (4-4-1) | L | 0 | 32 |
| Nov. 6 | at | *Duke (7-2-1) | L | 0 | 67 |
| Nov. 12 | vs | Wofford ( ) | W | 24 | 0 |
| Nov. 25 | vs | *Davidson (2-8) | W | 19 | 7 | at Charlotte, NC |
| | 3-6-0 | | 67 | 220 |
| 1936-Wake Forest (Southern) |
| Sep. 26 | vs | *North Carolina (8-2) | L | 7 | 14 | at Charlotte, NC |
| Oct. 3 | at | *North Carolina State (3-7) | W | 9 | 0 |
| Oct. 10 | vs | Wofford (1-7-1) | W | 32 | 0 |
| Oct. 16 | vs | *Clemson (5-5) | W | 6 | 0 |
| Oct. 23 | at | George Washington (7-1-1) | L | 12 | 13 |
| Oct. 31 | vs | Presbyterian (3-6) | W | 19 | 0 |
| Nov. 7 | vs | *Duke (9-1) | L | 0 | 20 |
| Nov. 13 | vs | Erskine (4-5) | W | 19 | 6 |
| Nov. 26 | at | *Davidson (5-4) | L | 6 | 19 |
| | 5-4-0 | | 110 | 72 |
| 1935-Wake Forest (Independent) |
| Sep. 21 | vs | Duke (8-2) | L | 7 | 26 | at Greensboro, NC |
| Sep. 28 | at | North Carolina (8-1) | L | 0 | 14 |
| Oct. 5 | at | Clemson (6-3) | L | 7 | 13 |
| Oct. 12 | at | North Carolina State (6-4) | L | 6 | 21 |
| Oct. 18 | vs | Furman (8-1) | L | 0 | 9 | at Charlotte, NC |
| Oct. 26 | vs | George Washington (6-3) | W | 7 | 6 |
| Nov. 1 | vs | Presbyterian (2-7) | W | 18 | 0 |
| Nov. 15 | at | Miami (Florida) ( ) | L | 0 | 3 |
| Nov. 28 | vs | Davidson (4-3-2) | L | 7 | 14 |
| | 2-7-0 | | 52 | 106 |
| 1934-Wake Forest (Independent) |
| Sep. 22 | vs | Guilford ( ) | W | 62 | 0 |
| Sep. 29 | at | North Carolina (7-1-1) | L | 0 | 21 |
| Oct. 6 | at | North Carolina State (2-6-1) | W | 13 | 12 |
| Oct. 11 | vs | Furman (5-4) | L | 2 | 3 | at Florence, SC |
| Oct. 20 | vs | Presbyterian ( ) | W | 14 | 6 |
| Oct. 26 | at | George Washington (6-3-1) | L | 2 | 6 |
| Nov. 3 | vs | Emory & Henry ( ) | L | 0 | 13 |
| Nov. 10 | at | Duke (7-2) | L | 7 | 28 |
| Nov. 17 | vs | Richmond (8-1) | L | 6 | 39 | at Charlotte, NC |
| Nov. 29 | at | Davidson (4-4-1) | L | 12 | 13 |
| | 3-7-0 | | 118 | 141 |
| 1933-Wake Forest (Independent) |
| Oct. 7 | at | Duke (9-1) | L | 0 | 22 |
| Oct. 21 | at | North Carolina State (1-5-3) | T | 0 | 0 |
| Oct. 28 | vs | Catholic ( ) | L | 0 | 12 |
| Nov. 4 | vs | Clemson (3-6-2) | L | 0 | 13 | at Charlotte, NC |
| Nov. 11 | at | North Carolina (4-5) | L | 0 | 26 |
| Nov. 30 | vs | Davidson (6-2-1) | L | 13 | 20 | at Charlotte, NC |
| | 0-5-1 | | 13 | 93 |
| 1932-Wake Forest (Independent) |
| Sep. 24 | at | North Carolina (3-5-2) | T | 0 | 0 |
| Oct. 8 | vs | South Carolina (5-4-2) | W | 6 | 0 | at Charlotte, NC |
| Oct. 15 | at | North Carolina State (6-1-2) | T | 0 | 0 |
| Oct. 21 | at | Duke (7-3) | L | 0 | 9 |
| Oct. 29 | at | Delaware ( ) | W | 7 | 0 |
| Nov. 5 | at | Catholic ( ) | L | 6 | 14 |
| Nov. 11 | vs | Carson-Newman ( ) | W | 20 | 6 |
| Nov. 24 | at | Davidson (4-4-1) | L | 0 | 7 |
| | 3-3-2 | | 39 | 36 |
| 1931-Wake Forest (Independent) |
| Sep. 26 | at | North Carolina (4-3-3) | L | 0 | 37 |
| Oct. 3 | vs | Furman ( ) | L | 7 | 36 | at Gastonia, NC |
| Oct. 16 | at | North Carolina State (3-6) | W | 6 | 0 |
| Oct. 23 | at | Duke (5-3-2) | L | 0 | 28 |
| Oct. 31 | vs | Erskine ( ) | W | 13 | 0 |
| Nov. 7 | vs | Presbyterian ( ) | W | 12 | 0 | at Greensboro, NC |
| Nov. 14 | at | Oglethorpe ( ) | L | 0 | 37 |
| Nov. 26 | vs | Davidson (4-4-2) | W | 7 | 0 | at Charlotte, NC |
| | 4-4-0 | | 45 | 138 |
| 1930-Wake Forest (Independent) |
| Sep. 27 | at | North Carolina (5-3-2) | L | 7 | 13 |
| Oct. 4 | vs | Guilford ( ) | W | 20 | 0 |
| Oct. 10 | vs | Baltimore ( ) | W | 44 | 0 |
| Oct. 16 | at | North Carolina State (2-8) | W | 7 | 0 |
| Oct. 25 | vs | Mercer ( ) | W | 21 | 0 |
| Nov. 1 | at | Temple (7-3) | L | 0 | 36 |
| Nov. 8 | vs | Presbyterian ( ) | L | 0 | 13 | at Asheville, NC |
| Nov. 22 | vs | Duke (8-1-2) | T | 13 | 13 |
| Nov. 27 | vs | Davidson (6-4) | W | 13 | 2 | at Charlotte, NC |
| | 5-3-1 | | 125 | 77 |
| 1929-Wake Forest (Independent) |
| Sep. 21 | vs | Catawba ( ) | W | 20 | 0 |
| Sep. 28 | at | North Carolina (9-1) | L | 0 | 48 |
| Oct. 5 | at | Richmond ( ) | W | 19 | 0 |
| Oct. 11 | vs | Elon ( ) | W | 25 | 6 |
| Oct. 17 | at | North Carolina State (1-8) | L | 6 | 8 |
| Oct. 26 | vs | Davidson (5-5) | W | 6 | 0 | at Greensboro, NC |
| Nov. 2 | at | Furman ( ) | L | 0 | 12 |
| Nov. 9 | at | Wofford ( ) | W | 18 | 0 |
| Nov. 16 | at | Navy (6-2-2) | L | 0 | 61 |
| Nov. 19 | vs | Presbyterian ( ) | T | 0 | 0 | at Greensboro, NC |
| Nov. 23 | at | Duke (4-6) | L | 0 | 20 |
| Nov. 28 | vs | Mercer ( ) | W | 13 | 0 | at Asheville, NC |
| | 6-5-1 | | 107 | 155 |
| 1928-Wake Forest (Independent) |
| Sep. 29 | at | North Carolina (5-3-2) | L | 0 | 65 |
| Oct. 6 | vs | Presbyterian ( ) | L | 7 | 12 |
| Oct. 13 | at | William & Mary ( ) | T | 0 | 0 |
| Oct. 18 | at | North Carolina State (4-5-1) | L | 0 | 37 |
| Oct. 27 | vs | Davidson (2-8) | W | 25 | 6 | at Charlotte, NC |
| Nov. 3 | vs | Furman (5-4) | L | 0 | 18 | at Charlotte, NC |
| Nov. 10 | at | Duke (5-5) | L | 0 | 38 |
| Nov. 16 | vs | Wofford ( ) | T | 7 | 7 |
| Nov. 29 | at | Mercer ( ) | L | 12 | 14 |
| Dec. 25 | at | Miami (Florida) ( ) | W | 13 | 6 |
| | 2-6-2 | | 64 | 203 |
| 1927-Wake Forest (Independent) |
| Sep. 24 | at | North Carolina (4-6) | W | 9 | 8 |
| Oct. 1 | vs | Elon ( ) | T | 0 | 0 |
| Oct. 7 | vs | Presbyterian ( ) | L | 7 | 14 | at Asheville, NC |
| Oct. 13 | at | North Carolina State (9-1) | L | 7 | 30 |
| Oct. 22 | vs | Davidson (4-4-1) | T | 13 | 13 |
| Oct. 29 | vs | Duke (4-5) | L | 6 | 32 |
| Nov. 5 | vs | Furman (10-1) | L | 0 | 53 |
| Nov. 11 | at | Quantico Marines ( ) | L | 10 | 39 |
| Nov. 19 | vs | High Point ( ) | W | 13 | 0 |
| Nov. 24 | vs | Mercer ( ) | L | 0 | 34 | at Asheville, NC |
| | 2-6-2 | | 65 | 223 |
| 1926-Wake Forest (Independent) |
| Sep. 25 | vs | North Carolina (4-5) | W | 13 | 0 |
| Oct. 2 | at | Wofford (2-8) | W | 27 | 0 |
| Oct. 9 | at | Furman (8-1-1) | L | 0 | 10 |
| Oct. 16 | at | Presbyterian (7-2) | L | 0 | 13 |
| Oct. 23 | vs | Davidson (7-2-1) | T | 3 | 3 | at Charlotte, NC |
| Oct. 30 | vs | Duke (3-6) | W | 21 | 0 | at Goldsboro, NC |
| Nov. 6 | vs | Elon ( ) | W | 53 | 0 |
| Nov. 13 | at | William & Mary ( ) | L | 6 | 13 |
| Nov. 20 | vs | Guilford ( ) | W | 60 | 0 |
| Nov. 27 | at | North Carolina State (4-6) | L | 3 | 7 |
| | 5-4-1 | | 186 | 46 |
| 1925-Wake Forest (Independent) |
| Sep. 26 | at | North Carolina (7-1-1) | W | 6 | 0 |
| Oct. 3 | vs | Davidson (6-2-2) | T | 7 | 7 | at Charlotte, NC |
| Oct. 10 | vs | Lenoir-Rhyne ( ) | W | 49 | 0 |
| Oct. 24 | at | Florida (8-2) | L | 3 | 24 |
| Oct. 31 | vs | Guilford ( ) | W | 25 | 0 |
| Nov. 7 | at | Duke (4-5) | W | 21 | 3 |
| Nov. 14 | at | North Carolina State (3-5-1) | L | 0 | 6 |
| Nov. 20 | vs | Furman (7-3) | W | 9 | 0 | at Asheville, NC |
| Nov. 26 | at | Elon ( ) | W | 65 | 0 |
| | 6-2-1 | | 185 | 40 |
| 1924-Wake Forest (Independent) |
| Sep. 27 | vs | North Carolina (4-5) | W | 7 | 6 |
| Oct. 11 | at | Washington & Lee (6-3-1) | W | 10 | 8 |
| Oct. 18 | vs | Florida (6-2-2) | L | 0 | 34 | at Tampa, FL |
| Oct. 25 | at | Lynchburg ( ) | W | 37 | 7 |
| Nov. 1 | vs | Guilford ( ) | W | 67 | 0 |
| Nov. 11 | at | Duke (4-5) | W | 32 | 0 |
| Nov. 22 | at | North Carolina State (2-6-2) | W | 12 | 0 |
| Nov. 27 | at | South Carolina (7-3) | L | 0 | 7 |
| Dec. 6 | vs | Elon ( ) | W | 42 | 0 |
| | 7-2-0 | | 207 | 62 |
| 1923-Wake Forest (Independent) |
| Sep. 29 | at | North Carolina (5-3-1) | L | 0 | 22 |
| Oct. 6 | vs | Guilford ( ) | W | 41 | 0 |
| Oct. 13 | vs | Lynchburg ( ) | W | 25 | 0 |
| Oct. 20 | vs | Davidson (3-7) | W | 6 | 0 | at Charlotte, NC |
| Oct. 27 | vs | Florida (6-1-2) | L | 7 | 16 | at Tampa, FL |
| Nov. 10 | vs | Duke (5-4) | W | 16 | 6 |
| Nov. 17 | vs | Elon ( ) | W | 9 | 6 |
| Nov. 24 | vs | North Carolina State (3-7) | W | 14 | 0 |
| Nov. 29 | at | South Carolina (4-6) | L | 7 | 14 |
| | 6-3-0 | | 125 | 64 |
| 1922-Wake Forest (Independent) |
| Sep. 23 | vs | Atlantic Christian ( ) | W | 34 | 0 |
| Sep. 30 | vs | North Carolina (9-1) | L | 3 | 62 | at neutral site |
| Oct. 7 | vs | Elon ( ) | W | 7 | 0 |
| Oct. 14 | vs | Davidson (2-6-2) | T | 6 | 6 | at Charlotte, NC |
| Oct. 21 | at | Lynchburg ( ) | L | 7 | 20 |
| Oct. 27 | at | Guilford ( ) | T | 0 | 0 |
| Nov. 4 | vs | William & Mary (6-3) | L | 0 | 18 |
| Nov. 11 | vs | Duke (7-2-1) | L | 0 | 3 |
| Nov. 25 | vs | North Carolina State (4-6) | L | 0 | 32 |
| Dec. 2 | vs | Hampden-Sydney (1-8) | W | 9 | 3 |
| | 3-5-2 | | 66 | 144 |
| 1921-Wake Forest (Independent) |
| Sep. 24 | at | Georgia Tech (8-1) | L | 0 | 42 |
| Oct. 1 | at | North Carolina (5-2-2) | L | 0 | 21 |
| Oct. 8 | at | Virginia Military Institute (3-5-1) | L | 0 | 20 |
| Oct. 15 | vs | Davidson (3-4-3) | W | 10 | 7 | at Charlotte, NC |
| Oct. 22 | at | William & Mary ( ) | L | 14 | 21 |
| Oct. 29 | vs | Guilford ( ) | W | 28 | 0 |
| Nov. 5 | at | Richmond (4-3-1) | L | 0 | 41 |
| Nov. 11 | vs | Duke ( ) | L | 0 | 17 |
| Nov. 19 | vs | North Carolina State (3-3-3) | L | 0 | 14 |
| Nov. 24 | at | Hampden-Sydney ( ) | L | 14 | 39 |
| | 2-8-0 | | 66 | 222 |
| 1920-Wake Forest (Independent) |
| Sep. 25 | at | Georgia Tech (8-1) | L | 0 | 44 |
| Oct. 2 | at | North Carolina (2-6) | L | 0 | 6 |
| Oct. 9 | at | Washington & Lee (5-3) | L | 0 | 27 |
| Oct. 16 | vs | Davidson (5-5) | L | 7 | 27 | at Charlotte, NC |
| Oct. 23 | at | Furman (9-1) | L | 0 | 17 |
| Oct. 30 | vs | Guilford ( ) | W | 48 | 6 |
| Nov. 6 | vs | Elon ( ) | W | 29 | 0 |
| Nov. 13 | at | Richmond ( ) | L | 7 | 20 |
| Nov. 25 | vs | North Carolina State (7-3) | L | 7 | 49 |
| | 2-7-0 | | 98 | 196 |
| 1919-Wake Forest (Independent) |
| Sep. 26 | vs | Davidson (4-6-1) | L | 0 | 21 |
| Oct. 4 | at | Georgia Tech (7-3) | L | 0 | 14 |
| Oct. 18 | at | North Carolina (4-3-1) | L | 0 | 6 |
| Oct. 25 | at | Furman (6-2-1) | L | 7 | 39 |
| Nov. 1 | at | Sewanee Club (Virginia) ( ) | W | 39 | 3 |
| Nov. 8 | at | Virginia Tech (5-4) | L | 0 | 40 |
| Nov. 15 | vs | Guilford ( ) | W | 65 | 0 |
| Nov. 27 | at | North Carolina State (7-2) | L | 7 | 21 |
| | 2-6-0 | | 118 | 144 |
| 1918-Wake Forest (Independent) |
| Nov. 9 | at | Virginia Tech (7-0) | L | 0 | 27 |
| Nov. 16 | at | Washington & Lee (1-2) | L | 7 | 20 |
| Nov. 23 | at | North Carolina State (1-3) | W | 21 | 0 |
| | 1-2-0 | | 28 | 47 |
| 1917-Wake Forest (Independent) |
| Sep. 29 | at | Georgia Tech (9-0) | L | 0 | 33 |
| Oct. 6 | at | Furman (3-5) | L | 6 | 7 |
| Oct. 13 | vs | Guilford ( ) | W | 20 | 0 |
| Oct. 18 | at | North Carolina State (6-2-1) | L | 6 | 17 |
| Oct. 27 | at | Maryland (4-3-1) | L | 13 | 29 |
| Nov. 3 | at | Virginia Tech (6-2-1) | L | 0 | 50 |
| Nov. 17 | at | Davidson (6-4) | L | 7 | 72 |
| Nov. 29 | vs | Hampden-Sydney ( ) | T | 7 | 7 |
| | 1-6-1 | | 59 | 215 |
| 1916-Wake Forest (Independent) |
| Sep. 30 | at | North Carolina (5-4) | L | 0 | 20 |
| Oct. 7 | vs | Guilford ( ) | W | 33 | 0 |
| Oct. 19 | vs | North Carolina State (2-5) | L | 0 | 6 |
| Nov. 4 | at | South Carolina (2-7) | W | 33 | 7 |
| Nov. 11 | at | Virginia Tech (7-2) | L | 0 | 52 |
| Nov. 18 | vs | Wofford (2-7) | W | 41 | 0 |
| | 3-3-0 | | 107 | 85 |
| 1915-Wake Forest (Independent) |
| Sep. 25 | vs | Florence YMCA ( ) | W | 80 | 0 |
| Oct. 9 | at | North Carolina (4-3-1) | L | 0 | 35 |
| Oct. 16 | vs | North Carolina State (3-3-1) | L | 0 | 7 |
| Oct. 30 | vs | Richmond Blues ( ) | W | 40 | 0 |
| Nov. 6 | at | Virginia Military Institute (6-2-1) | L | 6 | 21 |
| Nov. 11 | vs | Gallaudet ( ) | W | 28 | 6 |
| Nov. 25 | vs | Davidson (4-3-1) | L | 7 | 21 | at Charlotte, NC |
| | 3-4-0 | | 161 | 90 |
| 1914-Wake Forest (Independent) |
| Oct. 3 | at | North Carolina State (2-3-1) | L | 0 | 51 |
| Oct. 8 | vs | North Carolina (10-1) | L | 0 | 53 | at neutral site |
| Oct. 10 | vs | USS Franklin ( ) | W | 13 | 0 |
| Oct. 24 | at | Washington & Lee (9-0) | L | 0 | 72 |
| Oct. 31 | vs | Roanoke ( ) | W | 19 | 0 |
| Nov. 7 | at | South Carolina (5-5-1) | L | 0 | 26 |
| Nov. 14 | vs | North Carolina (10-1) | L | 7 | 12 | at neutral site |
| Nov. 26 | at | Davidson (5-1-1) | L | 6 | 7 |
| Dec. 5 | vs | Wofford (1-7-1) | W | 41 | 0 |
| | 3-6-0 | | 86 | 221 |
| 1913-Wake Forest (Independent) |
| Sep. 27 | at | North Carolina (5-4) | L | 0 | 7 |
| Oct. 11 | at | South Carolina (4-3) | L | 10 | 27 |
| Oct. 18 | vs | Richmond ( ) | L | 13 | 14 |
| Oct. 25 | vs | Washington & Lee (8-1) | L | 0 | 33 |
| Nov. 1 | vs | North Carolina State (6-1) | L | 0 | 37 |
| Nov. 8 | vs | Gallaudet ( ) | L | 7 | 47 |
| Nov. 15 | vs | North Carolina (5-4) | L | 0 | 29 | at neutral site |
| Nov. 27 | vs | Davidson (2-5) | L | 0 | 6 | at Charlotte, NC |
| | 0-8-0 | | 30 | 200 |
| 1912-Wake Forest (Independent) |
| Sep. 28 | vs | North Carolina Medical ( ) | W | 33 | 0 |
| Oct. 5 | at | South Carolina (5-2-1) | L | 3 | 10 |
| Oct. 12 | at | North Carolina (3-4-1) | L | 2 | 9 |
| Oct. 26 | at | Washington & Lee (8-1) | L | 0 | 20 |
| Nov. 2 | vs | North Carolina State (4-3) | L | 0 | 12 |
| Nov. 9 | vs | Virginia Medical ( ) | L | 14 | 23 |
| Nov. 16 | vs | Horner ( ) | W | 49 | 0 |
| Nov. 28 | vs | Davidson (3-4) | L | 7 | 13 | at Charlotte, NC |
| | 2-6-0 | | 108 | 87 |
| 1911-Wake Forest (Independent) |
| Sep. 30 | vs | Warrenton Preparatory ( ) | W | 52 | 0 |
| Oct. 7 | at | North Carolina (6-1-1) | L | 3 | 12 |
| Oct. 14 | vs | Roanoke ( ) | W | 62 | 0 |
| Oct. 21 | at | Washington & Lee (4-2-2) | L | 5 | 18 |
| Nov. 2 | at | Virginia (8-2) | L | 6 | 29 |
| Nov. 11 | vs | Davidson (5-3) | L | 0 | 9 | at Greensboro, NC |
| Nov. 18 | vs | North Carolina State (5-3) | L | 5 | 13 |
| Nov. 23 | vs | USS Franklin ( ) | W | 26 | 0 | at Durham, NC |
| | 3-5-0 | | 159 | 81 |
| 1910-Wake Forest (Independent) |
| Sep. 24 | vs | Warrenton Preparatory ( ) | W | 17 | 0 |
| Oct. 8 | vs | Horner ( ) | W | 28 | 0 |
| Oct. 22 | at | North Carolina (3-6) | L | 0 | 37 |
| Oct. 27 | at | South Carolina (4-4) | L | 0 | 6 |
| Oct. 29 | at | Citadel (3-4) | L | 5 | 9 |
| Nov. 12 | vs | USS Franklin ( ) | L | 0 | 11 |
| Nov. 19 | at | North Carolina State (4-0-2) | L | 3 | 28 |
| Nov. 24 | vs | Davidson (6-2) | L | 0 | 32 | at Charlotte, NC |
| Dec. 3 | vs | Norfolk Blues ( ) | L | 0 | 31 |
| | 2-7-0 | | 53 | 154 |
| 1909-Wake Forest (Independent) |
| Oct. 2 | at | North Carolina (5-2) | L | 0 | 18 |
| Oct. 4 | vs | Maryville ( ) | W | 3 | 0 |
| Oct. 16 | at | Washington & Lee (4-3) | L | 0 | 17 |
| Oct. 23 | at | South Carolina (2-6) | W | 8 | 0 |
| Nov. 5 | vs | Richmond (3-5-2) | L | 0 | 5 |
| Nov. 12 | vs | North Carolina Medical ( ) | L | 0 | 5 |
| | 2-4-0 | | 11 | 45 |
| 1908-Wake Forest (Independent) |
| Sep. 26 | at | North Carolina (3-3-3) | L | 0 | 17 |
| Sep. 30 | at | North Carolina State (6-1) | L | 0 | 76 |
| Oct. 3 | vs | Warrenton Preparatory ( ) | W | 21 | 0 |
| Oct. 10 | vs | Davidson (6-3-1) | L | 0 | 34 | at Charlotte, NC |
| Nov. 14 | vs | Davidson (6-3-1) | L | 0 | 31 | at Charlotte, NC |
| Nov. 21 | vs | North Carolina State (6-1) | L | 0 | 25 |
| | 1-5-0 | | 21 | 183 |
