| 2020-Purdue (Big Ten) |
| Oct. 24 | vs | *Iowa (6-2) | W | 24 | 20 |
| Oct. 31 | at | *Illinois (2-6) | W | 31 | 24 |
| Nov. 14 | vs | *Northwestern (7-2) | L | 20 | 27 |
| Nov. 20 | at | *Minnesota (3-4) | L | 31 | 34 |
| Nov. 28 | vs | *Rutgers (3-6) | L | 30 | 37 |
| Dec. 5 | vs | *Nebraska (3-5) | L | 27 | 37 |
| | 2-4-0 | | 163 | 179 |
| 2019-Purdue (Big Ten) |
| Aug. 30 | at | Nevada (7-6) | L | 31 | 34 |
| Sep. 7 | vs | Vanderbilt (3-9) | W | 42 | 24 |
| Sep. 14 | vs | Texas Christian (5-7) | L | 13 | 34 |
| Sep. 28 | vs | *Minnesota (11-2) | L | 31 | 38 |
| Oct. 5 | at | *Penn State (11-2) | L | 7 | 35 |
| Oct. 12 | vs | *Maryland (3-9) | W | 40 | 14 |
| Oct. 19 | at | *Iowa (10-3) | L | 20 | 26 |
| Oct. 26 | vs | *Illinois (6-7) | L | 6 | 24 |
| Nov. 2 | vs | *Nebraska (5-7) | W | 31 | 27 |
| Nov. 9 | at | *Northwestern (3-9) | W | 24 | 22 |
| Nov. 23 | at | *Wisconsin (10-4) | L | 24 | 45 |
| Nov. 30 | vs | *Indiana (8-5) | L | 41 | 44 |
| | 4-8-0 | | 310 | 367 |
| 2018-Purdue (Big Ten) |
| Aug. 30 | vs | *Northwestern (9-5) | L | 27 | 31 |
| Sep. 8 | vs | Eastern Michigan (7-6) | L | 19 | 20 |
| Sep. 15 | vs | Missouri (8-5) | L | 37 | 40 |
| Sep. 22 | vs | Boston College (7-5) | W | 30 | 13 |
| Sep. 29 | at | *Nebraska (4-8) | W | 42 | 28 |
| Oct. 13 | at | *Illinois (4-8) | W | 46 | 7 |
| Oct. 20 | vs | *Ohio State (13-1) | W | 49 | 20 |
| Oct. 27 | at | *Michigan State (7-6) | L | 13 | 23 |
| Nov. 3 | vs | *Iowa (9-4) | W | 38 | 36 |
| Nov. 10 | at | *Minnesota (7-6) | L | 10 | 41 |
| Nov. 17 | vs | *Wisconsin (8-5) | L | 44 | 47 |
| Nov. 24 | at | *Indiana (5-7) | W | 28 | 21 |
| Dec. 28 | vs | Auburn (8-5) | L | 14 | 63 | at Nashville, TN | Music City Bowl |
| | 6-7-0 | | 397 | 390 |
| 2017-Purdue (Big Ten) |
| Sep. 2 | vs | Louisville (8-5) | L | 28 | 35 | at Indianapolis, IN |
| Sep. 8 | vs | Ohio (9-4) | W | 44 | 21 |
| Sep. 16 | at | Missouri (7-6) | W | 35 | 3 |
| Sep. 23 | vs | *Michigan (8-5) | L | 10 | 28 |
| Oct. 7 | vs | *Minnesota (5-7) | W | 31 | 17 |
| Oct. 14 | at | *Wisconsin (13-1) | L | 9 | 17 |
| Oct. 21 | at | *Rutgers (4-8) | L | 12 | 14 |
| Oct. 28 | vs | *Nebraska (4-8) | L | 24 | 25 |
| Nov. 4 | vs | *Illinois (2-10) | W | 29 | 10 |
| Nov. 11 | at | *Northwestern (10-3) | L | 13 | 23 |
| Nov. 18 | at | *Iowa (8-5) | W | 24 | 15 |
| Nov. 25 | vs | *Indiana (5-7) | W | 31 | 24 |
| Dec. 27 | vs | Arizona (7-6) | W | 38 | 35 | at Santa Clara, CA | Foster Farms Bowl |
| | 7-6-0 | | 328 | 267 |
| 2016-Purdue (Big Ten) |
| Sep. 3 | vs | Eastern Kentucky ( ) | W | 45 | 24 |
| Sep. 10 | vs | Cincinnati (4-8) | L | 20 | 38 |
| Sep. 24 | vs | Nevada (5-7) | W | 24 | 14 |
| Oct. 1 | at | *Maryland (6-7) | L | 7 | 50 |
| Oct. 8 | at | *Illinois (3-9) | W | 34 | 31 |
| Oct. 15 | vs | *Iowa (8-5) | L | 35 | 49 |
| Oct. 22 | at | *Nebraska (9-4) | L | 14 | 27 |
| Oct. 29 | vs | *Penn State (11-3) | L | 24 | 62 |
| Nov. 5 | at | *Minnesota (9-4) | L | 31 | 44 |
| Nov. 12 | vs | *Northwestern (7-6) | L | 17 | 45 |
| Nov. 19 | vs | *Wisconsin (11-3) | L | 20 | 49 |
| Nov. 26 | at | *Indiana (6-7) | L | 24 | 26 |
| | 3-9-0 | | 295 | 459 |
| 2015-Purdue (Big Ten) |
| Sep. 6 | at | Marshall (10-3) | L | 31 | 41 |
| Sep. 12 | vs | Indiana State ( ) | W | 38 | 14 |
| Sep. 19 | vs | Virginia Tech (7-6) | L | 24 | 51 |
| Sep. 26 | vs | Bowling Green (10-4) | L | 28 | 35 |
| Oct. 3 | at | *Michigan State (12-2) | L | 21 | 24 |
| Oct. 10 | vs | *Minnesota (6-7) | L | 13 | 41 |
| Oct. 17 | at | *Wisconsin (10-3) | L | 7 | 24 |
| Oct. 31 | vs | *Nebraska (6-7) | W | 55 | 45 |
| Nov. 7 | vs | *Illinois (5-7) | L | 14 | 48 |
| Nov. 14 | at | *Northwestern (10-3) | L | 14 | 21 |
| Nov. 21 | at | *Iowa (12-2) | L | 20 | 40 |
| Nov. 28 | vs | *Indiana (6-7) | L | 36 | 54 |
| | 2-10-0 | | 301 | 438 |
| 2014-Purdue (Big Ten) |
| Aug. 30 | vs | Western Michigan (8-5) | W | 43 | 34 |
| Sep. 6 | vs | Central Michigan (7-6) | L | 17 | 38 |
| Sep. 13 | vs | Notre Dame (8-5) | L | 14 | 30 | at Indianapolis, IN |
| Sep. 20 | vs | Southern Illinois ( ) | W | 35 | 13 |
| Sep. 27 | vs | *Iowa (7-6) | L | 10 | 24 |
| Oct. 4 | at | *Illinois (6-7) | W | 38 | 27 |
| Oct. 11 | vs | *Michigan State (11-2) | L | 31 | 45 |
| Oct. 18 | at | *Minnesota (8-5) | L | 38 | 39 |
| Nov. 1 | at | *Nebraska (9-4) | L | 14 | 35 |
| Nov. 8 | vs | *Wisconsin (11-3) | L | 16 | 34 |
| Nov. 22 | vs | *Northwestern (5-7) | L | 14 | 38 |
| Nov. 29 | at | *Indiana (4-8) | L | 16 | 23 |
| | 3-9-0 | | 286 | 380 |
| 2013-Purdue (Big Ten) |
| Aug. 31 | at | Cincinnati (9-4) | L | 7 | 42 |
| Sep. 7 | vs | Indiana State ( ) | W | 20 | 14 |
| Sep. 14 | vs | Notre Dame (9-4) | L | 24 | 31 |
| Sep. 21 | at | *Wisconsin (9-4) | L | 10 | 41 |
| Sep. 28 | vs | Northern Illinois (12-2) | L | 24 | 55 |
| Oct. 12 | vs | *Nebraska (9-4) | L | 7 | 44 |
| Oct. 19 | at | *Michigan State (13-1) | L | 0 | 14 |
| Nov. 2 | vs | *Ohio State (12-2) | L | 0 | 56 |
| Nov. 9 | vs | *Iowa (8-5) | L | 14 | 38 |
| Nov. 16 | at | *Penn State (7-5) | L | 21 | 45 |
| Nov. 23 | vs | *Illinois (4-8) | L | 16 | 20 |
| Nov. 30 | at | *Indiana (5-7) | L | 36 | 56 |
| | 1-11-0 | | 179 | 456 |
| 2012-Purdue (Big Ten) |
| Sep. 1 | vs | Eastern Kentucky ( ) | W | 48 | 6 |
| Sep. 8 | at | Notre Dame (12-1) | L | 17 | 20 |
| Sep. 15 | vs | Eastern Michigan (2-10) | W | 54 | 16 |
| Sep. 29 | vs | Marshall (5-7) | W | 51 | 41 |
| Oct. 6 | vs | *Michigan (8-5) | L | 13 | 44 |
| Oct. 13 | vs | *Wisconsin (8-6) | L | 14 | 38 |
| Oct. 20 | at | *Ohio State (12-0) | L | 22 | 29 |
| Oct. 27 | at | *Minnesota (6-7) | L | 28 | 44 |
| Nov. 3 | vs | *Penn State (8-4) | L | 9 | 34 |
| Nov. 10 | at | *Iowa (4-8) | W | 27 | 24 |
| Nov. 17 | at | *Illinois (2-10) | W | 20 | 17 |
| Nov. 24 | vs | *Indiana (4-8) | W | 56 | 35 |
| Jan. 1 | vs | Oklahoma State (8-5) | L | 14 | 58 | at Dallas, TX | Heart of Dallas Bowl |
| | 6-7-0 | | 373 | 406 |
| 2011-Purdue (Big Ten) |
| Sep. 3 | vs | Middle Tennessee State (2-10) | W | 27 | 24 |
| Sep. 10 | at | Rice (4-8) | L | 22 | 24 |
| Sep. 17 | vs | Southeast Missouri State ( ) | W | 59 | 0 |
| Oct. 1 | vs | Notre Dame (8-5) | L | 10 | 38 |
| Oct. 8 | vs | *Minnesota (3-9) | W | 45 | 17 |
| Oct. 15 | at | *Penn State (9-4) | L | 18 | 23 |
| Oct. 22 | vs | *Illinois (7-6) | W | 21 | 14 |
| Oct. 29 | at | *Michigan (11-2) | L | 14 | 36 |
| Nov. 5 | at | *Wisconsin (11-3) | L | 17 | 62 |
| Nov. 12 | vs | *Ohio State (6-7) | W | 26 | 23 |
| Nov. 19 | vs | *Iowa (7-6) | L | 21 | 31 |
| Nov. 26 | at | *Indiana (1-11) | W | 33 | 25 |
| Dec. 27 | vs | Western Michigan (7-6) | W | 37 | 32 | at Detroit, MI | Little Caesars Bowl |
| | 7-6-0 | | 350 | 349 |
| 2010-Purdue (Big Ten) |
| Sep. 4 | at | Notre Dame (8-5) | L | 12 | 23 |
| Sep. 11 | vs | Western Illinois ( ) | W | 31 | 21 |
| Sep. 18 | vs | Ball State (4-8) | W | 24 | 13 |
| Sep. 25 | vs | Toledo (8-5) | L | 20 | 31 |
| Oct. 9 | at | *Northwestern (7-6) | W | 20 | 17 |
| Oct. 16 | vs | *Minnesota (3-9) | W | 28 | 17 |
| Oct. 23 | at | *Ohio State (12-1) | L | 0 | 49 |
| Oct. 30 | at | *Illinois (7-6) | L | 10 | 44 |
| Nov. 6 | vs | *Wisconsin (11-2) | L | 13 | 34 |
| Nov. 13 | vs | *Michigan (7-6) | L | 16 | 27 |
| Nov. 20 | at | *Michigan State (11-2) | L | 31 | 35 |
| Nov. 27 | vs | *Indiana (5-7) | L | 31 | 34 |
| | 4-8-0 | | 236 | 345 |
| 2009-Purdue (Big Ten) |
| Sep. 5 | vs | Toledo (5-7) | W | 52 | 31 |
| Sep. 12 | at | Oregon (10-3) | L | 36 | 38 |
| Sep. 19 | vs | Northern Illinois (7-6) | L | 21 | 28 |
| Sep. 26 | vs | Notre Dame (6-6) | L | 21 | 24 |
| Oct. 3 | vs | *Northwestern (8-5) | L | 21 | 27 |
| Oct. 10 | at | *Minnesota (6-7) | L | 20 | 35 |
| Oct. 17 | vs | *Ohio State (11-2) | W | 26 | 18 |
| Oct. 24 | vs | *Illinois (3-9) | W | 24 | 14 |
| Oct. 31 | at | *Wisconsin (10-3) | L | 0 | 37 |
| Nov. 7 | at | *Michigan (5-7) | W | 38 | 36 |
| Nov. 14 | vs | *Michigan State (6-7) | L | 37 | 40 |
| Nov. 21 | at | *Indiana (4-8) | W | 38 | 21 |
| | 5-7-0 | | 334 | 349 |
| 2008-Purdue (Big Ten) |
| Sep. 6 | vs | Northern Colorado ( ) | W | 42 | 10 |
| Sep. 13 | vs | Oregon (10-3) | L | 26 | 32 |
| Sep. 20 | vs | Central Michigan (8-5) | W | 32 | 25 |
| Sep. 27 | at | Notre Dame (7-6) | L | 21 | 38 |
| Oct. 4 | vs | *Penn State (11-2) | L | 6 | 20 |
| Oct. 11 | at | *Ohio State (10-3) | L | 3 | 16 |
| Oct. 18 | at | *Northwestern (9-4) | L | 26 | 48 |
| Oct. 25 | vs | *Minnesota (7-6) | L | 6 | 17 |
| Nov. 1 | vs | *Michigan (3-9) | W | 48 | 42 |
| Nov. 8 | at | *Michigan State (9-4) | L | 7 | 21 |
| Nov. 15 | at | *Iowa (9-4) | L | 17 | 22 |
| Nov. 22 | vs | *Indiana (3-9) | W | 62 | 10 |
| | 4-8-0 | | 296 | 301 |
| 2007-Purdue (Big Ten) |
| Sep. 1 | at | Toledo (5-7) | W | 52 | 24 |
| Sep. 8 | vs | Eastern Illinois ( ) | W | 52 | 6 |
| Sep. 15 | vs | Central Michigan (8-6) | W | 45 | 22 |
| Sep. 22 | at | *Minnesota (1-11) | W | 45 | 31 |
| Sep. 29 | vs | Notre Dame (3-9) | W | 33 | 19 |
| Oct. 6 | vs | *Ohio State (11-2) | L | 7 | 23 |
| Oct. 13 | at | *Michigan (9-4) | L | 21 | 48 |
| Oct. 20 | vs | *Iowa (6-6) | W | 31 | 6 |
| Oct. 27 | vs | *Northwestern (6-6) | W | 35 | 17 |
| Nov. 3 | at | *Penn State (9-4) | L | 19 | 26 |
| Nov. 10 | vs | *Michigan State (7-6) | L | 31 | 48 |
| Nov. 17 | at | *Indiana (7-6) | L | 24 | 27 |
| Dec. 26 | vs | Central Michigan (8-6) | W | 51 | 48 | at Detroit, MI | Motor City Bowl |
| | 8-5-0 | | 446 | 345 |
| 2006-Purdue (Big Ten) |
| Sep. 2 | vs | Indiana State ( ) | W | 60 | 35 |
| Sep. 9 | vs | Miami (Ohio) (2-10) | W | 38 | 31 |
| Sep. 16 | vs | Ball State (5-7) | W | 38 | 28 |
| Sep. 23 | vs | *Minnesota (6-7) | W | 27 | 21 |
| Sep. 30 | at | Notre Dame (10-3) | L | 21 | 35 |
| Oct. 7 | at | *Iowa (6-7) | L | 17 | 47 |
| Oct. 14 | at | *Northwestern (4-8) | W | 31 | 10 |
| Oct. 21 | vs | *Wisconsin (12-1) | L | 3 | 24 |
| Oct. 28 | vs | *Penn State (9-4) | L | 0 | 12 |
| Nov. 4 | at | *Michigan State (4-8) | W | 17 | 15 |
| Nov. 11 | at | *Illinois (2-10) | W | 42 | 31 |
| Nov. 18 | vs | *Indiana (5-7) | W | 28 | 19 |
| Nov. 25 | at | Hawaii (11-3) | L | 35 | 42 |
| Dec. 29 | vs | Maryland (9-4) | L | 7 | 24 | at Orlando, FL | Champs Sports Bowl |
| | 8-6-0 | | 364 | 374 |
| 2005-Purdue (Big Ten) |
| Sep. 10 | vs | Akron (7-6) | W | 49 | 24 |
| Sep. 17 | at | Arizona (3-8) | W | 31 | 24 |
| Sep. 24 | at | *Minnesota (7-5) | L | 35 | 42 |
| Oct. 1 | vs | Notre Dame (9-3) | L | 28 | 49 |
| Oct. 8 | vs | *Iowa (7-5) | L | 17 | 34 |
| Oct. 15 | vs | *Northwestern (7-5) | L | 29 | 34 |
| Oct. 22 | at | *Wisconsin (10-3) | L | 20 | 31 |
| Oct. 29 | at | *Penn State (11-1) | L | 15 | 33 |
| Nov. 5 | vs | *Michigan State (5-6) | W | 28 | 21 |
| Nov. 12 | vs | *Illinois (2-9) | W | 37 | 3 |
| Nov. 19 | at | *Indiana (4-7) | W | 41 | 14 |
| | 5-6-0 | | 330 | 309 |
| 2004-Purdue (Big Ten) |
| Sep. 5 | vs | Syracuse (6-6) | W | 51 | 0 |
| Sep. 11 | vs | Ball State (2-9) | W | 59 | 7 |
| Sep. 25 | at | *Illinois (3-8) | W | 38 | 30 |
| Oct. 2 | at | Notre Dame (6-6) | W | 41 | 16 |
| Oct. 9 | at | *Penn State (4-7) | W | 20 | 13 |
| Oct. 16 | vs | *Wisconsin (9-3) | L | 17 | 20 |
| Oct. 23 | vs | *Michigan (9-3) | L | 14 | 16 |
| Oct. 30 | at | *Northwestern (6-6) | L | 10 | 13 |
| Nov. 6 | at | *Iowa (10-2) | L | 21 | 23 |
| Nov. 13 | vs | *Ohio State (8-4) | W | 24 | 17 |
| Nov. 20 | vs | *Indiana (3-8) | W | 63 | 24 |
| Dec. 31 | vs | Arizona State (9-3) | L | 23 | 27 | at El Paso, TX | Sun Bowl |
| | 7-5-0 | | 381 | 206 |
| 2003-Purdue (Big Ten) |
| Sep. 6 | vs | Bowling Green (11-3) | L | 26 | 27 |
| Sep. 13 | at | Wake Forest (5-7) | W | 16 | 10 |
| Sep. 20 | vs | Arizona (2-10) | W | 59 | 7 |
| Sep. 27 | vs | Notre Dame (5-7) | W | 23 | 10 |
| Oct. 4 | vs | *Illinois (1-11) | W | 43 | 10 |
| Oct. 11 | vs | *Penn State (3-9) | W | 28 | 14 |
| Oct. 18 | at | *Wisconsin (7-6) | W | 26 | 23 |
| Oct. 25 | at | *Michigan (10-3) | L | 3 | 31 |
| Nov. 1 | vs | *Northwestern (6-7) | W | 34 | 14 |
| Nov. 8 | vs | *Iowa (10-3) | W | 27 | 14 |
| Nov. 15 | at | *Ohio State (11-2) | L | 13 | 16 |
| Nov. 22 | at | *Indiana (2-10) | W | 24 | 16 |
| Jan. 1 | vs | Georgia (11-3) | L | 27 | 34 | at Orlando, FL | Capital One Bowl |
| | 9-4-0 | | 349 | 226 |
| 2002-Purdue (Big Ten) |
| Aug. 31 | vs | Illinois State ( ) | W | 51 | 10 |
| Sep. 7 | at | Notre Dame (10-3) | L | 17 | 24 |
| Sep. 14 | vs | Western Michigan (4-8) | W | 28 | 24 |
| Sep. 21 | vs | Wake Forest (7-6) | L | 21 | 24 |
| Sep. 28 | vs | *Minnesota (8-5) | W | 28 | 15 |
| Oct. 5 | at | *Iowa (11-2) | L | 28 | 31 |
| Oct. 12 | at | *Illinois (5-7) | L | 31 | 38 |
| Oct. 19 | vs | *Michigan (10-3) | L | 21 | 23 |
| Oct. 26 | at | *Northwestern (3-9) | W | 42 | 13 |
| Nov. 9 | vs | *Ohio State (14-0) | L | 6 | 10 |
| Nov. 16 | at | *Michigan State (4-8) | W | 45 | 42 |
| Nov. 23 | vs | *Indiana (3-9) | W | 34 | 10 |
| Dec. 31 | vs | Washington (7-6) | W | 34 | 24 | at El Paso, TX | Sun Bowl |
| | 7-6-0 | | 386 | 288 |
| 2001-Purdue (Big Ten) |
| Sep. 2 | at | Cincinnati (7-5) | W | 19 | 14 |
| Sep. 22 | vs | Akron (4-7) | W | 33 | 14 |
| Sep. 29 | at | *Minnesota (4-7) | W | 35 | 28 |
| Oct. 6 | vs | *Iowa (7-5) | W | 23 | 14 |
| Oct. 13 | at | *Michigan (8-4) | L | 10 | 24 |
| Oct. 27 | vs | *Northwestern (4-7) | W | 32 | 27 |
| Nov. 3 | vs | *Illinois (10-2) | L | 13 | 38 |
| Nov. 10 | at | *Ohio State (7-5) | L | 9 | 35 |
| Nov. 17 | vs | *Michigan State (7-5) | W | 24 | 14 |
| Nov. 24 | at | *Indiana (5-6) | L | 7 | 13 |
| Dec. 1 | vs | Notre Dame (5-6) | L | 18 | 24 |
| Dec. 31 | vs | Washington State (10-2) | L | 27 | 33 | at El Paso, TX | Sun Bowl |
| | 6-6-0 | | 250 | 278 |
| 2000-Purdue (Big Ten) |
| Sep. 2 | vs | Central Michigan (2-9) | W | 48 | 0 |
| Sep. 9 | vs | Kent State (1-10) | W | 45 | 10 |
| Sep. 16 | at | Notre Dame (9-3) | L | 21 | 23 |
| Sep. 23 | vs | *Minnesota (6-6) | W | 38 | 24 |
| Sep. 30 | at | *Penn State (5-7) | L | 20 | 22 |
| Oct. 7 | vs | *Michigan (9-3) | W | 32 | 31 |
| Oct. 14 | at | *Northwestern (8-4) | W | 41 | 28 |
| Oct. 21 | at | *Wisconsin (9-4) | W | 30 | 24 |
| Oct. 28 | vs | *Ohio State (8-4) | W | 31 | 27 |
| Nov. 11 | at | *Michigan State (5-6) | L | 10 | 30 |
| Nov. 18 | vs | *Indiana (3-8) | W | 41 | 13 |
| Jan. 1 | vs | Washington (11-1) | L | 24 | 34 | at Pasadena, CA | Rose Bowl |
| | 8-4-0 | | 381 | 266 |
| 1999-Purdue (Big Ten) |
| Sep. 4 | at | Central Florida (4-7) | W | 47 | 13 |
| Sep. 11 | vs | Notre Dame (5-7) | W | 28 | 23 |
| Sep. 18 | vs | Central Michigan (4-7) | W | 58 | 16 |
| Sep. 25 | vs | *Northwestern (3-8) | W | 31 | 23 |
| Oct. 2 | at | *Michigan (10-2) | L | 12 | 38 |
| Oct. 9 | at | *Ohio State (6-6) | L | 22 | 25 |
| Oct. 16 | vs | *Michigan State (10-2) | W | 52 | 28 |
| Oct. 23 | vs | *Penn State (10-3) | L | 25 | 31 |
| Oct. 30 | at | *Minnesota (8-4) | W | 33 | 28 |
| Nov. 6 | vs | *Wisconsin (10-2) | L | 21 | 28 |
| Nov. 20 | at | *Indiana (4-7) | W | 30 | 24 |
| Jan. 1 | vs | Georgia (8-4) | L | 25 | 28 | at Tampa, FL | Outback Bowl |
| | 7-5-0 | | 384 | 305 |
| 1998-Purdue (Big Ten) |
| Aug. 30 | vs | Southern California (8-5) | L | 17 | 27 | at Los Angeles, CA | Pigskin Classic |
| Sep. 12 | vs | Rice (5-6) | W | 21 | 19 |
| Sep. 19 | vs | Central Florida (9-2) | W | 35 | 7 |
| Sep. 26 | at | Notre Dame (9-3) | L | 30 | 31 |
| Oct. 3 | vs | *Minnesota (5-6) | W | 56 | 21 |
| Oct. 10 | at | *Wisconsin (11-1) | L | 24 | 31 |
| Oct. 17 | at | *Penn State (9-3) | L | 13 | 31 |
| Oct. 24 | vs | *Illinois (3-8) | W | 42 | 9 |
| Oct. 31 | vs | *Iowa (3-8) | W | 36 | 14 |
| Nov. 7 | at | *Northwestern (3-9) | W | 56 | 21 |
| Nov. 14 | at | *Michigan State (6-6) | W | 25 | 24 |
| Nov. 21 | vs | *Indiana (4-7) | W | 52 | 7 |
| Dec. 29 | vs | Kansas State (11-2) | W | 37 | 34 | at San Antonio, TX | Alamo Bowl |
| | 9-4-0 | | 444 | 276 |
| 1997-Purdue (Big Ten) |
| Sep. 6 | at | Toledo (9-3) | L | 22 | 36 |
| Sep. 13 | vs | Notre Dame (7-6) | W | 28 | 17 |
| Sep. 20 | vs | Ball State (5-6) | W | 28 | 14 |
| Sep. 27 | vs | *Northwestern (5-7) | W | 21 | 9 |
| Oct. 11 | at | *Minnesota (3-9) | W | 59 | 43 |
| Oct. 18 | vs | *Wisconsin (8-5) | W | 45 | 20 |
| Oct. 25 | at | *Illinois (0-11) | W | 48 | 3 |
| Nov. 1 | at | *Iowa (7-5) | L | 17 | 35 |
| Nov. 8 | vs | *Michigan State (7-5) | W | 22 | 21 |
| Nov. 15 | vs | *Penn State (9-3) | L | 17 | 42 |
| Nov. 22 | at | *Indiana (2-9) | W | 56 | 7 |
| Dec. 30 | vs | Oklahoma State (8-4) | W | 33 | 20 | at San Antonio, TX | Alamo Bowl |
| | 9-3-0 | | 396 | 267 |
| 1996-Purdue (Big Ten) |
| Aug. 31 | at | *Michigan State (6-6) | L | 14 | 52 |
| Sep. 14 | at | Notre Dame (8-3) | L | 0 | 35 |
| Sep. 21 | vs | West Virginia (8-4) | L | 6 | 20 |
| Sep. 28 | vs | North Carolina State (3-8) | W | 42 | 21 |
| Oct. 5 | vs | *Minnesota (4-7) | W | 30 | 27 |
| Oct. 12 | at | *Penn State (11-2) | L | 14 | 31 |
| Oct. 19 | vs | *Ohio State (11-1) | L | 14 | 42 |
| Nov. 2 | at | *Wisconsin (8-5) | L | 25 | 33 |
| Nov. 9 | vs | *Michigan (8-4) | W | 9 | 3 |
| Nov. 16 | at | *Northwestern (9-3) | L | 24 | 27 |
| Nov. 23 | vs | *Indiana (3-8) | L | 16 | 33 |
| | 3-8-0 | | 194 | 324 |
| 1995-Purdue (Big Ten) |
| Sep. 2 | at | West Virginia (5-6) | W | 26 | 24 |
| Sep. 9 | vs | Notre Dame (9-3) | L | 28 | 35 |
| Sep. 23 | vs | *Michigan State (6-5-1) | T | 35 | 35 |
| Sep. 30 | vs | Ball State (7-4) | W | 35 | 13 |
| Oct. 7 | at | *Minnesota (3-8) | L | 38 | 39 |
| Oct. 14 | vs | *Penn State (9-3) | L | 23 | 26 |
| Oct. 21 | at | *Ohio State (11-2) | L | 0 | 28 |
| Nov. 4 | vs | *Wisconsin (4-5-2) | W | 38 | 27 |
| Nov. 11 | at | *Michigan (9-4) | L | 0 | 5 |
| Nov. 18 | vs | *Northwestern (10-2) | L | 8 | 23 |
| Nov. 24 | at | *Indiana (2-9) | W | 51 | 14 |
| | 4-6-1 | | 282 | 269 |
| 1994-Purdue (Big Ten) |
| Sep. 10 | vs | Toledo (6-4-1) | W | 51 | 17 |
| Sep. 17 | vs | Ball State (5-5-1) | W | 49 | 21 |
| Sep. 24 | at | Notre Dame (6-5-1) | L | 21 | 39 |
| Oct. 1 | at | *Illinois (7-5) | W | 22 | 16 |
| Oct. 8 | vs | *Minnesota (3-8) | W | 49 | 37 |
| Oct. 15 | at | *Wisconsin (7-4-1) | T | 27 | 27 |
| Oct. 22 | at | *Ohio State (9-4) | L | 14 | 48 |
| Oct. 29 | vs | *Iowa (5-5-1) | T | 21 | 21 |
| Nov. 5 | vs | *Michigan (8-4) | L | 23 | 45 |
| Nov. 12 | at | *Michigan State (5-6) | L | 30 | 42 |
| Nov. 19 | vs | *Indiana (6-5) | L | 29 | 33 |
| | 4-5-2 | | 336 | 346 |
| 1993-Purdue (Big Ten) |
| Sep. 4 | at | North Carolina State (7-5) | L | 7 | 20 |
| Sep. 11 | vs | Western Michigan (7-3-1) | W | 28 | 13 |
| Sep. 25 | vs | Notre Dame (11-1) | L | 0 | 17 |
| Oct. 2 | vs | *Illinois (5-6) | L | 10 | 28 |
| Oct. 9 | at | *Minnesota (4-7) | L | 56 | 59 |
| Oct. 16 | vs | *Wisconsin (10-1-1) | L | 28 | 42 |
| Oct. 23 | vs | *Ohio State (10-1-1) | L | 24 | 45 |
| Oct. 30 | at | *Iowa (6-6) | L | 17 | 26 |
| Nov. 6 | at | *Michigan (8-4) | L | 10 | 25 |
| Nov. 13 | vs | *Michigan State (6-6) | L | 24 | 27 |
| Nov. 20 | at | *Indiana (8-4) | L | 17 | 24 |
| | 1-10-0 | | 221 | 326 |
| 1992-Purdue (Big Ten) |
| Sep. 12 | vs | California (4-7) | W | 41 | 14 |
| Sep. 19 | vs | Toledo (8-3) | L | 29 | 33 |
| Sep. 26 | at | Notre Dame (10-1-1) | L | 0 | 48 |
| Oct. 3 | vs | *Northwestern (3-8) | L | 14 | 28 |
| Oct. 10 | vs | *Minnesota (2-9) | W | 24 | 20 |
| Oct. 17 | at | *Wisconsin (5-6) | L | 16 | 19 |
| Oct. 24 | at | *Iowa (5-7) | W | 27 | 16 |
| Oct. 31 | vs | *Michigan (9-0-3) | L | 17 | 24 |
| Nov. 7 | at | *Illinois (6-5-1) | L | 17 | 20 |
| Nov. 14 | at | *Michigan State (5-6) | L | 13 | 35 |
| Nov. 21 | vs | *Indiana (5-6) | W | 13 | 10 |
| | 4-7-0 | | 211 | 267 |
| 1991-Purdue (Big Ten) |
| Sep. 7 | vs | Eastern Michigan (3-7-1) | W | 49 | 3 |
| Sep. 14 | at | California (10-2) | L | 18 | 42 |
| Sep. 28 | vs | Notre Dame (10-3) | L | 20 | 45 |
| Oct. 5 | at | *Northwestern (3-8) | W | 17 | 14 |
| Oct. 12 | at | *Minnesota (2-9) | L | 3 | 6 |
| Oct. 19 | vs | *Wisconsin (5-6) | W | 28 | 7 |
| Oct. 26 | vs | *Iowa (10-1-1) | L | 21 | 31 |
| Nov. 2 | at | *Michigan (10-2) | L | 0 | 42 |
| Nov. 9 | vs | *Illinois (6-6) | L | 14 | 41 |
| Nov. 16 | vs | *Michigan State (3-8) | W | 27 | 17 |
| Nov. 23 | at | *Indiana (7-4-1) | L | 22 | 24 |
| | 4-7-0 | | 219 | 272 |
| 1990-Purdue (Big Ten) |
| Sep. 15 | vs | Washington (10-2) | L | 14 | 20 |
| Sep. 22 | vs | Indiana State ( ) | W | 41 | 13 |
| Sep. 29 | at | Notre Dame (9-3) | L | 11 | 37 |
| Oct. 6 | vs | *Minnesota (6-5) | L | 7 | 19 |
| Oct. 13 | at | *Illinois (8-4) | L | 0 | 34 |
| Oct. 20 | vs | *Ohio State (7-4-1) | L | 2 | 42 |
| Oct. 27 | at | *Michigan State (8-3-1) | L | 33 | 55 |
| Nov. 3 | vs | *Michigan (9-3) | L | 13 | 38 |
| Nov. 10 | at | *Northwestern (2-9) | W | 33 | 13 |
| Nov. 17 | at | *Iowa (8-4) | L | 9 | 38 |
| Nov. 24 | vs | *Indiana (6-5-1) | L | 14 | 28 |
| | 2-9-0 | | 177 | 337 |
| 1989-Purdue (Big Ten) |
| Sep. 9 | vs | Miami (Ohio) (2-8-1) | W | 27 | 10 |
| Sep. 16 | at | Washington (8-4) | L | 9 | 38 |
| Sep. 30 | vs | Notre Dame (12-1) | L | 7 | 40 |
| Oct. 7 | at | *Minnesota (6-5) | L | 15 | 35 |
| Oct. 14 | vs | *Illinois (10-2) | L | 2 | 14 |
| Oct. 21 | at | *Ohio State (8-4) | L | 3 | 21 |
| Oct. 28 | vs | *Michigan State (8-4) | L | 21 | 28 |
| Nov. 4 | at | *Michigan (10-2) | L | 27 | 42 |
| Nov. 11 | vs | *Northwestern (0-11) | W | 46 | 15 |
| Nov. 18 | vs | *Iowa (5-6) | L | 0 | 24 |
| Nov. 25 | at | *Indiana (5-6) | W | 15 | 14 |
| | 3-8-0 | | 172 | 281 |
| 1988-Purdue (Big Ten) |
| Sep. 10 | vs | Washington (6-5) | L | 6 | 20 |
| Sep. 17 | vs | Ohio (4-6-1) | W | 33 | 10 |
| Sep. 24 | at | Notre Dame (12-0) | L | 7 | 52 |
| Oct. 1 | vs | *Minnesota (2-7-2) | W | 14 | 10 |
| Oct. 8 | at | *Illinois (6-5-1) | L | 0 | 20 |
| Oct. 15 | at | *Ohio State (4-6-1) | W | 31 | 26 |
| Oct. 22 | vs | *Iowa (6-4-3) | L | 7 | 31 |
| Oct. 29 | at | *Wisconsin (1-10) | W | 9 | 6 |
| Nov. 5 | vs | *Michigan State (6-5-1) | L | 3 | 48 |
| Nov. 12 | at | *Northwestern (2-8-1) | L | 7 | 28 |
| Nov. 19 | vs | *Indiana (8-3-1) | L | 7 | 52 |
| | 4-7-0 | | 124 | 303 |
| 1987-Purdue (Big Ten) |
| Sep. 12 | at | Washington (7-4-1) | L | 10 | 28 |
| Sep. 19 | vs | Louisville (3-7-1) | T | 22 | 22 |
| Sep. 26 | vs | Notre Dame (8-4) | L | 20 | 44 |
| Oct. 3 | at | *Minnesota (6-5) | L | 19 | 21 |
| Oct. 10 | vs | *Illinois (3-7-1) | W | 9 | 3 |
| Oct. 17 | vs | *Ohio State (6-4-1) | L | 17 | 20 |
| Oct. 24 | at | *Iowa (10-3) | L | 14 | 38 |
| Oct. 31 | vs | *Wisconsin (3-8) | W | 49 | 14 |
| Nov. 7 | at | *Michigan State (9-2-1) | L | 3 | 45 |
| Nov. 14 | vs | *Northwestern (2-8-1) | W | 20 | 15 |
| Nov. 21 | at | *Indiana (8-4) | L | 14 | 35 |
| | 3-7-1 | | 197 | 285 |
| 1986-Purdue (Big Ten) |
| Sep. 13 | vs | Ball State (6-5) | W | 20 | 3 |
| Sep. 20 | vs | Pittsburgh (5-5-1) | L | 26 | 41 |
| Sep. 27 | at | Notre Dame (5-6) | L | 9 | 41 |
| Oct. 4 | vs | *Minnesota (6-6) | L | 9 | 36 |
| Oct. 11 | at | *Illinois (4-7) | L | 27 | 34 |
| Oct. 18 | vs | *Ohio State (10-3) | L | 11 | 39 |
| Oct. 25 | at | *Michigan State (6-5) | L | 3 | 37 |
| Nov. 1 | at | *Northwestern (4-7) | W | 17 | 16 |
| Nov. 8 | vs | *Michigan (11-2) | L | 7 | 31 |
| Nov. 15 | at | *Iowa (9-3) | L | 14 | 42 |
| Nov. 22 | vs | *Indiana (6-6) | W | 17 | 15 |
| | 3-8-0 | | 160 | 335 |
| 1985-Purdue (Big Ten) |
| Aug. 31 | at | Pittsburgh (5-5-1) | L | 30 | 31 |
| Sep. 21 | vs | Ball State (4-7) | W | 37 | 18 |
| Sep. 28 | vs | Notre Dame (5-6) | W | 35 | 17 |
| Oct. 5 | at | *Minnesota (7-5) | L | 15 | 45 |
| Oct. 12 | vs | *Illinois (6-5-1) | W | 30 | 24 |
| Oct. 19 | at | *Ohio State (9-3) | L | 27 | 41 |
| Oct. 26 | vs | *Michigan State (7-5) | L | 24 | 28 |
| Nov. 2 | vs | *Northwestern (3-8) | W | 31 | 7 |
| Nov. 9 | at | *Michigan (10-1-1) | L | 0 | 47 |
| Nov. 16 | vs | *Iowa (10-2) | L | 24 | 27 |
| Nov. 23 | at | *Indiana (4-7) | W | 34 | 21 |
| | 5-6-0 | | 287 | 306 |
| 1984-Purdue (Big Ten) |
| Sep. 8 | vs | Notre Dame (7-5) | W | 23 | 21 | at Indianapolis, IN |
| Sep. 15 | vs | Miami (Florida) (8-5) | L | 17 | 28 |
| Sep. 22 | vs | *Minnesota (4-7) | W | 34 | 10 |
| Sep. 29 | at | *Michigan State (6-6) | W | 13 | 10 |
| Oct. 6 | vs | *Ohio State (9-3) | W | 28 | 23 |
| Oct. 13 | vs | *Iowa (8-4-1) | L | 3 | 40 |
| Oct. 20 | at | *Illinois (7-4) | L | 20 | 34 |
| Oct. 27 | at | *Northwestern (2-9) | W | 49 | 7 |
| Nov. 3 | vs | *Michigan (6-6) | W | 31 | 29 |
| Nov. 10 | at | *Wisconsin (7-4-1) | L | 13 | 30 |
| Nov. 17 | vs | *Indiana (0-11) | W | 31 | 24 |
| Dec. 31 | vs | Virginia (8-2-2) | L | 24 | 27 | at Atlanta, GA | Peach Bowl |
| | 7-5-0 | | 286 | 283 |
| 1983-Purdue (Big Ten) |
| Sep. 10 | vs | Notre Dame (7-5) | L | 6 | 52 |
| Sep. 17 | at | Miami (Florida) (11-1) | L | 0 | 35 |
| Sep. 24 | at | *Minnesota (1-10) | W | 32 | 20 |
| Oct. 1 | vs | *Michigan State (4-6-1) | T | 29 | 29 |
| Oct. 8 | at | *Ohio State (9-3) | L | 22 | 33 |
| Oct. 15 | at | *Iowa (9-3) | L | 14 | 31 |
| Oct. 22 | vs | *Illinois (10-2) | L | 21 | 35 |
| Oct. 29 | vs | *Northwestern (2-9) | W | 48 | 17 |
| Nov. 5 | at | *Michigan (9-3) | L | 10 | 42 |
| Nov. 12 | vs | *Wisconsin (7-4) | L | 38 | 42 |
| Nov. 19 | at | *Indiana (3-8) | W | 31 | 30 |
| | 3-7-1 | | 251 | 366 |
| 1982-Purdue (Big Ten) |
| Sep. 11 | vs | Stanford (5-6) | L | 14 | 35 |
| Sep. 18 | vs | *Minnesota (3-8) | L | 10 | 36 |
| Sep. 25 | at | Notre Dame (6-4-1) | L | 14 | 28 |
| Oct. 2 | vs | *Wisconsin (7-5) | L | 31 | 35 |
| Oct. 9 | at | *Illinois (7-5) | L | 34 | 38 |
| Oct. 16 | vs | *Northwestern (3-8) | W | 34 | 21 |
| Oct. 23 | at | *Michigan State (2-9) | W | 24 | 21 |
| Oct. 30 | at | *Ohio State (9-3) | L | 6 | 38 |
| Nov. 6 | vs | *Iowa (8-4) | W | 16 | 7 |
| Nov. 13 | at | *Michigan (8-4) | L | 21 | 52 |
| Nov. 20 | vs | *Indiana (5-6) | L | 7 | 13 |
| | 3-8-0 | | 211 | 324 |
| 1981-Purdue (Big Ten) |
| Sep. 12 | vs | Stanford (4-7) | W | 27 | 19 |
| Sep. 19 | at | *Minnesota (6-5) | L | 13 | 16 |
| Sep. 26 | vs | Notre Dame (5-6) | W | 15 | 14 |
| Oct. 3 | at | *Wisconsin (7-5) | L | 14 | 20 |
| Oct. 10 | vs | *Illinois (7-4) | W | 44 | 20 |
| Oct. 17 | at | *Northwestern (0-11) | W | 35 | 0 |
| Oct. 24 | vs | *Michigan State (5-6) | W | 27 | 26 |
| Oct. 31 | vs | *Ohio State (9-3) | L | 33 | 45 |
| Nov. 7 | at | *Iowa (8-4) | L | 7 | 33 |
| Nov. 14 | vs | *Michigan (9-3) | L | 10 | 28 |
| Nov. 21 | at | *Indiana (3-8) | L | 17 | 20 |
| | 5-6-0 | | 242 | 241 |
| 1980-Purdue (Big Ten) |
| Sep. 6 | at | Notre Dame (9-2-1) | L | 10 | 31 |
| Sep. 13 | at | *Wisconsin (4-7) | W | 12 | 6 |
| Sep. 20 | vs | UCLA (9-2) | L | 14 | 23 |
| Oct. 4 | vs | Miami (Ohio) (5-6) | W | 28 | 3 |
| Oct. 11 | vs | *Minnesota (5-6) | W | 21 | 7 |
| Oct. 18 | at | *Illinois (3-7-1) | W | 45 | 20 |
| Oct. 25 | vs | *Michigan State (3-8) | W | 36 | 25 |
| Nov. 1 | at | *Northwestern (0-11) | W | 52 | 31 |
| Nov. 8 | vs | *Iowa (4-7) | W | 58 | 13 |
| Nov. 15 | at | *Michigan (10-2) | L | 0 | 26 |
| Nov. 22 | vs | *Indiana (6-5) | W | 24 | 23 |
| Dec. 27 | vs | Missouri (8-4) | W | 28 | 25 | at Memphis, TN | Liberty Bowl |
| | 9-3-0 | | 328 | 233 |
| 1979-Purdue (Big Ten) |
| Sep. 8 | vs | *Wisconsin (4-7) | W | 41 | 20 |
| Sep. 15 | at | UCLA (5-6) | L | 21 | 31 |
| Sep. 22 | vs | Notre Dame (7-4) | W | 28 | 22 |
| Sep. 29 | vs | Oregon (6-5) | W | 13 | 7 |
| Oct. 6 | at | *Minnesota (4-6-1) | L | 14 | 31 |
| Oct. 13 | vs | *Illinois (2-8-1) | W | 28 | 14 |
| Oct. 20 | at | *Michigan State (5-6) | W | 14 | 7 |
| Oct. 27 | vs | *Northwestern (1-10) | W | 20 | 16 |
| Nov. 3 | at | *Iowa (5-6) | W | 20 | 14 |
| Nov. 10 | vs | *Michigan (8-4) | W | 24 | 21 |
| Nov. 17 | at | *Indiana (8-4) | W | 37 | 21 |
| Dec. 31 | vs | Tennessee (7-5) | W | 27 | 22 | at Houston, TX | Bluebonnet Bowl |
| | 10-2-0 | | 287 | 226 |
| 1978-Purdue (Big Ten) |
| Sep. 16 | vs | *Michigan State (8-3) | W | 21 | 14 |
| Sep. 23 | vs | Ohio (3-8) | W | 24 | 0 |
| Sep. 30 | at | Notre Dame (9-3) | L | 6 | 10 |
| Oct. 7 | vs | Wake Forest (1-10) | W | 14 | 7 |
| Oct. 14 | vs | *Ohio State (7-4-1) | W | 27 | 16 |
| Oct. 21 | at | *Illinois (1-8-2) | W | 13 | 0 |
| Oct. 28 | at | *Iowa (2-9) | W | 34 | 7 |
| Nov. 4 | vs | *Northwestern (0-10-1) | W | 31 | 0 |
| Nov. 11 | at | *Wisconsin (5-4-2) | T | 24 | 24 |
| Nov. 18 | at | *Michigan (10-2) | L | 6 | 24 |
| Nov. 25 | vs | *Indiana (4-7) | W | 20 | 7 |
| Dec. 25 | vs | Georgia Tech (7-5) | W | 41 | 21 | at Atlanta, GA | Peach Bowl |
| | 9-2-1 | | 261 | 130 |
| 1977-Purdue (Big Ten) |
| Sep. 10 | at | *Michigan State (7-3-1) | L | 14 | 19 |
| Sep. 17 | vs | Ohio (1-10) | W | 44 | 7 |
| Sep. 24 | vs | Notre Dame (11-1) | L | 24 | 31 |
| Oct. 1 | vs | Wake Forest (1-10) | W | 26 | 17 |
| Oct. 8 | at | *Ohio State (9-3) | L | 0 | 46 |
| Oct. 15 | vs | *Illinois (3-8) | L | 22 | 29 |
| Oct. 22 | vs | *Iowa (4-7) | W | 34 | 21 |
| Oct. 29 | at | *Northwestern (1-10) | W | 28 | 16 |
| Nov. 5 | at | *Wisconsin (5-6) | W | 22 | 0 |
| Nov. 12 | vs | *Michigan (10-2) | L | 7 | 40 |
| Nov. 19 | at | *Indiana (5-5-1) | L | 10 | 21 |
| | 5-6-0 | | 231 | 247 |
| 1976-Purdue (Big Ten) |
| Sep. 11 | vs | *Northwestern (1-10) | W | 31 | 19 |
| Sep. 18 | at | Notre Dame (9-3) | L | 0 | 23 |
| Sep. 25 | vs | Southern California (11-1) | L | 13 | 31 |
| Oct. 2 | vs | Miami (Ohio) (3-8) | W | 42 | 20 |
| Oct. 9 | at | *Wisconsin (5-6) | W | 18 | 16 |
| Oct. 16 | vs | *Illinois (5-6) | L | 17 | 21 |
| Oct. 23 | at | *Ohio State (9-2-1) | L | 3 | 24 |
| Oct. 30 | at | *Michigan State (4-6-1) | L | 13 | 45 |
| Nov. 6 | vs | *Michigan (10-2) | W | 16 | 14 |
| Nov. 13 | at | *Iowa (5-6) | W | 21 | 0 |
| Nov. 20 | vs | *Indiana (5-6) | L | 14 | 20 |
| | 5-6-0 | | 188 | 233 |
| 1975-Purdue (Big Ten) |
| Sep. 13 | at | *Northwestern (3-8) | L | 25 | 31 |
| Sep. 20 | vs | Notre Dame (8-3) | L | 0 | 17 |
| Sep. 27 | at | Southern California (8-4) | L | 6 | 19 |
| Oct. 4 | vs | Miami (Ohio) (11-1) | L | 3 | 14 |
| Oct. 11 | vs | *Wisconsin (4-6-1) | L | 14 | 17 |
| Oct. 18 | at | *Illinois (5-6) | W | 26 | 24 |
| Oct. 25 | vs | *Ohio State (11-1) | L | 6 | 35 |
| Nov. 1 | vs | *Michigan State (7-4) | W | 20 | 10 |
| Nov. 8 | at | *Michigan (8-2-2) | L | 0 | 28 |
| Nov. 15 | vs | *Iowa (3-8) | W | 19 | 18 |
| Nov. 22 | at | *Indiana (2-8-1) | W | 9 | 7 |
| | 4-7-0 | | 128 | 220 |
| 1974-Purdue (Big Ten) |
| Sep. 14 | vs | *Wisconsin (7-4) | L | 14 | 28 |
| Sep. 21 | vs | Miami (Ohio) (10-0-1) | T | 7 | 7 |
| Sep. 28 | at | Notre Dame (10-2) | W | 31 | 20 |
| Oct. 5 | at | Duke (6-5) | L | 14 | 16 |
| Oct. 12 | vs | *Illinois (6-4-1) | L | 23 | 27 |
| Oct. 19 | at | *Northwestern (3-8) | W | 31 | 26 |
| Oct. 26 | at | *Michigan State (7-3-1) | L | 7 | 31 |
| Nov. 2 | vs | *Iowa (3-8) | W | 38 | 14 |
| Nov. 9 | vs | *Minnesota (4-7) | L | 20 | 24 |
| Nov. 16 | at | *Michigan (10-1) | L | 0 | 51 |
| Nov. 23 | vs | *Indiana (1-10) | W | 38 | 17 |
| | 4-6-1 | | 223 | 261 |
| 1973-Purdue (Big Ten) |
| Sep. 15 | at | *Wisconsin (4-7) | W | 14 | 13 |
| Sep. 22 | vs | Miami (Ohio) (11-0) | L | 19 | 24 |
| Sep. 29 | vs | Notre Dame (11-0) | L | 7 | 20 |
| Oct. 6 | vs | Duke (2-8-1) | W | 27 | 7 |
| Oct. 13 | at | *Illinois (5-6) | L | 13 | 15 |
| Oct. 20 | vs | *Northwestern (4-7) | W | 21 | 10 |
| Oct. 27 | vs | *Michigan State (5-6) | L | 7 | 10 |
| Nov. 3 | at | *Iowa (0-11) | W | 48 | 23 |
| Nov. 10 | at | *Minnesota (7-4) | L | 7 | 34 |
| Nov. 17 | vs | *Michigan (10-0-1) | L | 9 | 34 |
| Nov. 24 | at | *Indiana (2-9) | W | 28 | 23 |
| | 5-6-0 | | 200 | 213 |
| 1972-Purdue (Big Ten) |
| Sep. 16 | vs | Bowling Green (6-3-1) | L | 14 | 17 |
| Sep. 23 | vs | Washington (8-3) | L | 21 | 22 |
| Sep. 30 | at | Notre Dame (8-3) | L | 14 | 35 |
| Oct. 7 | at | *Iowa (3-7-1) | W | 24 | 0 |
| Oct. 14 | at | *Minnesota (4-7) | W | 28 | 3 |
| Oct. 21 | vs | *Northwestern (2-9) | W | 37 | 0 |
| Oct. 28 | vs | *Illinois (3-8) | W | 20 | 14 |
| Nov. 4 | at | *Michigan State (5-5-1) | L | 12 | 22 |
| Nov. 11 | vs | *Wisconsin (4-7) | W | 27 | 6 |
| Nov. 18 | at | *Michigan (10-1) | L | 6 | 9 |
| Nov. 25 | vs | *Indiana (5-6) | W | 42 | 7 |
| | 6-5-0 | | 245 | 135 |
| 1971-Purdue (Big Ten) |
| Sep. 18 | at | Washington (8-3) | L | 35 | 38 |
| Sep. 25 | vs | Notre Dame (8-2) | L | 7 | 8 |
| Oct. 2 | vs | *Iowa (1-10) | W | 45 | 13 |
| Oct. 9 | vs | *Minnesota (4-7) | W | 27 | 13 |
| Oct. 16 | at | *Northwestern (7-4) | W | 21 | 20 |
| Oct. 23 | at | *Illinois (5-6) | L | 7 | 21 |
| Oct. 30 | vs | *Michigan State (6-5) | L | 10 | 43 |
| Nov. 6 | at | *Wisconsin (4-6-1) | L | 10 | 14 |
| Nov. 13 | vs | *Michigan (11-1) | L | 17 | 20 |
| Nov. 20 | at | *Indiana (3-8) | L | 31 | 38 |
| | 3-7-0 | | 210 | 228 |
| 1970-Purdue (Big Ten) |
| Sep. 19 | vs | Texas Christian (4-6-1) | W | 15 | 0 |
| Sep. 26 | at | Notre Dame (10-1) | L | 0 | 48 |
| Oct. 3 | at | Stanford (9-3) | W | 26 | 14 |
| Oct. 10 | vs | *Michigan (9-1) | L | 0 | 29 |
| Oct. 17 | at | *Iowa (3-6-1) | W | 24 | 3 |
| Oct. 24 | at | *Northwestern (6-4) | L | 14 | 38 |
| Oct. 31 | vs | *Illinois (3-7) | L | 21 | 23 |
| Nov. 7 | at | *Michigan State (4-6) | L | 14 | 24 |
| Nov. 14 | vs | *Ohio State (9-1) | L | 7 | 10 |
| Nov. 21 | vs | *Indiana (1-9) | W | 40 | 0 |
| | 4-6-0 | | 161 | 189 |
| 1969-Purdue (Big Ten) |
| Sep. 20 | at | Texas Christian (4-6) | W | 42 | 35 |
| Sep. 27 | vs | Notre Dame (8-2-1) | W | 28 | 14 |
| Oct. 4 | vs | Stanford (7-2-1) | W | 36 | 35 |
| Oct. 11 | at | *Michigan (8-3) | L | 20 | 31 |
| Oct. 18 | vs | *Iowa (5-5) | W | 35 | 31 |
| Oct. 25 | vs | *Northwestern (3-7) | W | 45 | 20 |
| Nov. 1 | at | *Illinois (0-10) | W | 49 | 22 |
| Nov. 8 | vs | *Michigan State (4-6) | W | 41 | 13 |
| Nov. 15 | at | *Ohio State (8-1) | L | 14 | 42 |
| Nov. 22 | at | *Indiana (4-6) | W | 44 | 21 |
| | 8-2-0 | | 354 | 264 |
| 1968-Purdue (Big Ten) |
| Sep. 21 | vs | Virginia (7-3) | W | 44 | 6 |
| Sep. 28 | at | Notre Dame (7-2-1) | W | 37 | 22 |
| Oct. 5 | at | *Northwestern (1-9) | W | 43 | 6 |
| Oct. 12 | at | *Ohio State (10-0) | L | 0 | 13 |
| Oct. 19 | vs | Wake Forest (2-7-1) | W | 28 | 27 |
| Oct. 26 | vs | *Iowa (5-5) | W | 44 | 14 |
| Nov. 2 | vs | *Illinois (1-9) | W | 35 | 17 |
| Nov. 9 | at | *Minnesota (6-4) | L | 13 | 27 |
| Nov. 16 | at | *Michigan State (5-5) | W | 9 | 0 |
| Nov. 23 | vs | *Indiana (6-4) | W | 38 | 35 |
| | 8-2-0 | | 291 | 167 |
| 1967-Purdue (Big Ten) |
| Sep. 23 | vs | Texas A&M (7-4) | W | 24 | 20 | at Dallas, TX |
| Sep. 30 | vs | Notre Dame (8-2) | W | 28 | 21 |
| Oct. 7 | vs | *Northwestern (3-7) | W | 25 | 16 |
| Oct. 14 | at | *Ohio State (6-3) | W | 41 | 6 |
| Oct. 21 | vs | Oregon State (7-2-1) | L | 14 | 22 |
| Oct. 28 | at | *Iowa (1-8-1) | W | 41 | 22 |
| Nov. 4 | at | *Illinois (4-6) | W | 42 | 9 |
| Nov. 11 | vs | *Minnesota (8-2) | W | 41 | 12 |
| Nov. 18 | vs | *Michigan State (3-7) | W | 21 | 7 |
| Nov. 25 | at | *Indiana (9-2) | L | 14 | 19 |
| | 8-2-0 | | 291 | 154 |
| 1966-Purdue (Big Ten) |
| Sep. 17 | vs | Ohio (5-5) | W | 42 | 3 |
| Sep. 24 | at | Notre Dame (9-0-1) | L | 14 | 26 |
| Oct. 1 | vs | Southern Methodist (8-3) | W | 35 | 23 |
| Oct. 8 | vs | *Iowa (2-8) | W | 35 | 0 |
| Oct. 15 | at | *Michigan (6-4) | W | 22 | 21 |
| Oct. 22 | at | *Michigan State (9-0-1) | L | 20 | 41 |
| Oct. 29 | vs | *Illinois (4-6) | W | 25 | 21 |
| Nov. 5 | at | *Wisconsin (3-6-1) | W | 23 | 0 |
| Nov. 12 | at | *Minnesota (4-5-1) | W | 16 | 0 |
| Nov. 19 | vs | *Indiana (1-8-1) | W | 51 | 6 |
| Jan. 2 | vs | Southern California (7-4) | W | 14 | 13 | at Pasadena, CA | Rose Bowl |
| | 9-2-0 | | 297 | 154 |
| 1965-Purdue (Big Ten) |
| Sep. 18 | vs | Miami (Ohio) (7-3) | W | 38 | 0 |
| Sep. 25 | vs | Notre Dame (7-2-1) | W | 25 | 21 |
| Oct. 2 | vs | Southern Methodist (4-5-1) | T | 14 | 14 | at Dallas, TX |
| Oct. 9 | at | *Iowa (1-9) | W | 17 | 14 |
| Oct. 16 | at | *Michigan (4-6) | W | 17 | 15 |
| Oct. 23 | vs | *Michigan State (10-1) | L | 10 | 14 |
| Oct. 30 | at | *Illinois (6-4) | L | 0 | 21 |
| Nov. 6 | vs | *Wisconsin (2-7-1) | W | 45 | 7 |
| Nov. 13 | vs | *Minnesota (5-4-1) | W | 35 | 0 |
| Nov. 20 | at | *Indiana (2-8) | W | 26 | 21 |
| | 7-2-1 | | 227 | 127 |
| 1964-Purdue (Big Ten) |
| Sep. 26 | vs | Ohio (5-4-1) | W | 17 | 0 |
| Oct. 3 | at | Notre Dame (9-1) | L | 15 | 34 |
| Oct. 10 | vs | *Wisconsin (3-6) | W | 28 | 7 |
| Oct. 17 | at | *Michigan (9-1) | W | 21 | 20 |
| Oct. 24 | at | *Iowa (3-6) | W | 19 | 14 |
| Oct. 31 | vs | *Illinois (6-3) | W | 26 | 14 |
| Nov. 7 | at | *Michigan State (4-5) | L | 7 | 21 |
| Nov. 14 | at | *Minnesota (5-4) | L | 7 | 14 |
| Nov. 21 | vs | *Indiana (2-7) | W | 28 | 22 |
| | 6-3-0 | | 168 | 146 |
| 1963-Purdue (Big Ten) |
| Sep. 28 | at | Miami (Florida) (3-7) | L | 0 | 3 |
| Oct. 5 | vs | Notre Dame (2-7) | W | 7 | 6 |
| Oct. 12 | at | *Wisconsin (5-4) | L | 20 | 38 |
| Oct. 19 | at | *Michigan (3-4-2) | W | 23 | 12 |
| Oct. 26 | vs | *Iowa (3-3-2) | W | 14 | 0 |
| Nov. 2 | at | *Illinois (8-1-1) | L | 21 | 41 |
| Nov. 9 | vs | *Michigan State (6-2-1) | L | 0 | 23 |
| Nov. 16 | vs | *Minnesota (3-6) | W | 13 | 11 |
| Nov. 30 | at | *Indiana (3-6) | W | 21 | 15 |
| | 5-4-0 | | 119 | 149 |
| 1962-Purdue (Big Ten) |
| Sep. 22 | at | Washington (7-1-2) | T | 7 | 7 |
| Oct. 6 | at | Notre Dame (5-5) | W | 24 | 6 |
| Oct. 13 | vs | Miami (Ohio) (8-2-1) | L | 7 | 10 |
| Oct. 20 | vs | *Michigan (2-7) | W | 37 | 0 |
| Oct. 27 | at | *Iowa (4-5) | W | 26 | 3 |
| Nov. 3 | vs | *Illinois (2-7) | L | 10 | 14 |
| Nov. 10 | at | *Michigan State (5-4) | W | 17 | 9 |
| Nov. 17 | at | *Minnesota (6-2-1) | L | 6 | 7 |
| Nov. 24 | vs | *Indiana (3-6) | L | 7 | 12 |
| | 4-4-1 | | 141 | 68 |
| 1961-Purdue (Big Ten) |
| Sep. 23 | at | Washington (5-4-1) | W | 13 | 6 |
| Oct. 7 | vs | Notre Dame (5-5) | L | 20 | 22 |
| Oct. 14 | vs | Miami (Ohio) ( ) | W | 19 | 6 |
| Oct. 21 | at | *Michigan (6-3) | L | 14 | 16 |
| Oct. 28 | vs | *Iowa (5-4) | W | 9 | 0 |
| Nov. 4 | at | *Illinois (0-9) | W | 23 | 9 |
| Nov. 11 | vs | *Michigan State (7-2) | W | 7 | 6 |
| Nov. 18 | at | *Minnesota (8-2) | L | 7 | 10 |
| Nov. 25 | at | *Indiana (2-7) | W | 34 | 12 |
| | 6-3-0 | | 146 | 87 |
| 1960-Purdue (Big Ten) |
| Sep. 24 | vs | UCLA (7-2-1) | T | 27 | 27 |
| Oct. 1 | at | Notre Dame (2-8) | W | 51 | 19 |
| Oct. 8 | at | *Wisconsin (4-5) | L | 13 | 24 |
| Oct. 15 | vs | *Ohio State (7-2) | W | 24 | 21 |
| Oct. 22 | at | *Iowa (8-1) | L | 14 | 21 |
| Oct. 29 | vs | *Illinois (5-4) | L | 12 | 14 |
| Nov. 5 | vs | *Michigan State (6-2-1) | L | 13 | 17 |
| Nov. 12 | at | *Minnesota (8-2) | W | 23 | 14 |
| Nov. 19 | vs | *Indiana (1-8) | W | 35 | 6 |
| | 4-4-1 | | 212 | 163 |
| 1959-Purdue (Big Ten) |
| Sep. 18 | at | UCLA (5-4-1) | T | 0 | 0 |
| Oct. 3 | vs | Notre Dame (5-5) | W | 28 | 7 |
| Oct. 10 | vs | *Wisconsin (7-3) | W | 21 | 0 |
| Oct. 17 | at | *Ohio State (3-5-1) | L | 0 | 15 |
| Oct. 24 | vs | *Iowa (5-4) | W | 14 | 7 |
| Oct. 31 | at | *Illinois (5-3-1) | T | 7 | 7 |
| Nov. 7 | at | *Michigan State (5-4) | L | 0 | 15 |
| Nov. 14 | vs | *Minnesota (2-7) | W | 29 | 23 |
| Nov. 21 | at | *Indiana (4-4-1) | W | 10 | 7 |
| | 5-2-2 | | 109 | 81 |
| 1958-Purdue (Big Ten) |
| Sep. 27 | vs | Nebraska (3-7) | W | 28 | 0 |
| Oct. 4 | at | Rice (5-5) | W | 24 | 0 |
| Oct. 11 | at | *Wisconsin (7-1-1) | L | 6 | 31 |
| Oct. 18 | vs | *Michigan State (3-5-1) | W | 14 | 6 |
| Oct. 25 | at | Notre Dame (6-4) | W | 29 | 22 |
| Nov. 1 | vs | *Illinois (4-5) | W | 31 | 8 |
| Nov. 8 | at | *Ohio State (6-1-2) | T | 14 | 14 |
| Nov. 15 | at | *Northwestern (5-4) | W | 23 | 6 |
| Nov. 22 | vs | *Indiana (5-3-1) | T | 15 | 15 |
| | 6-1-2 | | 184 | 102 |
| 1957-Purdue (Big Ten) |
| Sep. 28 | vs | Notre Dame (7-3) | L | 0 | 12 |
| Oct. 5 | at | *Minnesota (4-5) | L | 17 | 21 |
| Oct. 12 | vs | *Wisconsin (6-3) | L | 14 | 23 |
| Oct. 19 | at | *Michigan State (8-1) | W | 20 | 13 |
| Oct. 26 | vs | Miami (Ohio) ( ) | W | 37 | 6 |
| Nov. 2 | at | *Illinois (4-5) | W | 21 | 6 |
| Nov. 9 | at | *Ohio State (9-1) | L | 7 | 20 |
| Nov. 16 | vs | *Northwestern (0-9) | W | 27 | 0 |
| Nov. 23 | at | *Indiana (1-8) | W | 35 | 13 |
| | 5-4-0 | | 178 | 114 |
| 1956-Purdue (Big Ten) |
| Sep. 29 | vs | Missouri (4-5-1) | W | 16 | 7 |
| Oct. 6 | at | *Minnesota (6-1-2) | L | 14 | 21 |
| Oct. 13 | at | Notre Dame (2-8) | W | 28 | 14 |
| Oct. 20 | at | *Wisconsin (1-5-3) | T | 6 | 6 |
| Oct. 27 | vs | *Iowa (9-1) | L | 20 | 21 |
| Nov. 3 | vs | *Illinois (2-5-2) | T | 7 | 7 |
| Nov. 10 | at | *Michigan State (7-2) | L | 9 | 12 |
| Nov. 17 | at | *Northwestern (4-4-1) | L | 0 | 14 |
| Nov. 24 | vs | *Indiana (3-6) | W | 39 | 20 |
| | 3-4-2 | | 139 | 122 |
| 1955-Purdue (Big Ten) |
| Sep. 24 | vs | Pacific (5-4) | W | 14 | 7 |
| Oct. 1 | at | *Minnesota (3-6) | W | 7 | 6 |
| Oct. 8 | vs | *Wisconsin (4-5) | L | 0 | 9 |
| Oct. 15 | at | *Iowa (3-5-1) | T | 20 | 20 |
| Oct. 22 | vs | Notre Dame (8-2) | L | 7 | 22 |
| Oct. 29 | at | *Illinois (5-3-1) | W | 13 | 0 |
| Nov. 5 | vs | *Michigan State (9-1) | L | 0 | 27 |
| Nov. 12 | vs | *Northwestern (0-8-1) | W | 46 | 8 |
| Nov. 19 | at | *Indiana (3-6) | W | 6 | 4 |
| | 5-3-1 | | 113 | 103 |
| 1954-Purdue (Big Ten) |
| Sep. 25 | vs | Missouri (4-5-1) | W | 31 | 0 |
| Oct. 2 | at | Notre Dame (9-1) | W | 27 | 14 |
| Oct. 9 | vs | Duke (8-2-1) | T | 13 | 13 |
| Oct. 16 | at | *Wisconsin (7-2) | L | 6 | 20 |
| Oct. 23 | at | *Michigan State (3-6) | W | 27 | 13 |
| Oct. 30 | vs | *Illinois (1-8) | W | 28 | 14 |
| Nov. 6 | at | *Iowa (5-4) | L | 14 | 25 |
| Nov. 13 | vs | *Ohio State (10-0) | L | 6 | 28 |
| Nov. 20 | vs | *Indiana (3-6) | W | 13 | 7 |
| | 5-3-1 | | 165 | 134 |
| 1953-Purdue (Big Ten) |
| Sep. 26 | at | Missouri (6-4) | L | 7 | 14 |
| Oct. 3 | vs | Notre Dame (9-0-1) | L | 7 | 37 |
| Oct. 10 | at | Duke (7-2-1) | L | 14 | 20 |
| Oct. 17 | vs | *Wisconsin (6-2-1) | L | 19 | 28 |
| Oct. 24 | vs | *Michigan State (9-1) | W | 6 | 0 |
| Oct. 31 | at | *Illinois (7-1-1) | L | 0 | 21 |
| Nov. 7 | vs | *Iowa (5-3-1) | L | 0 | 26 |
| Nov. 14 | at | *Ohio State (6-3) | L | 6 | 21 |
| Nov. 21 | at | *Indiana (2-7) | W | 30 | 0 |
| | 2-7-0 | | 89 | 167 |
| 1952-Purdue (Western) |
| Sep. 27 | at | Penn State (7-2-1) | T | 20 | 20 |
| Oct. 4 | at | *Ohio State (6-3) | W | 21 | 14 |
| Oct. 11 | vs | *Iowa (2-7) | W | 41 | 14 |
| Oct. 18 | vs | Notre Dame (7-2-1) | L | 14 | 26 |
| Oct. 25 | at | *Illinois (4-5) | W | 40 | 12 |
| Nov. 1 | vs | Michigan State (9-0) | L | 7 | 14 |
| Nov. 8 | at | *Minnesota (4-3-2) | T | 14 | 14 |
| Nov. 15 | at | *Michigan (5-4) | L | 10 | 21 |
| Nov. 22 | vs | *Indiana (2-7) | W | 21 | 16 |
| | 4-3-2 | | 188 | 151 |
| 1951-Purdue (Western) |
| Sep. 29 | vs | Texas (7-3) | L | 0 | 14 |
| Oct. 6 | vs | *Iowa (2-5-2) | W | 34 | 30 |
| Oct. 12 | at | Miami (Florida) (8-3) | L | 0 | 7 |
| Oct. 20 | vs | *Wisconsin (7-1-1) | L | 7 | 31 |
| Oct. 27 | at | Notre Dame (7-2-1) | L | 9 | 30 |
| Nov. 3 | vs | Penn State (5-4) | W | 28 | 0 |
| Nov. 10 | at | *Northwestern (5-4) | W | 35 | 14 |
| Nov. 17 | vs | *Minnesota (2-6-1) | W | 19 | 13 |
| Nov. 24 | at | *Indiana (2-7) | W | 21 | 13 |
| | 5-4-0 | | 153 | 152 |
| 1950-Purdue (Western) |
| Sep. 30 | at | Texas (9-2) | L | 26 | 34 |
| Oct. 7 | at | Notre Dame (4-4-1) | W | 28 | 14 |
| Oct. 14 | vs | Miami (Florida) (9-1-1) | L | 14 | 20 |
| Oct. 21 | at | *Iowa (3-5-1) | L | 21 | 33 |
| Oct. 28 | vs | UCLA (6-3) | L | 6 | 20 |
| Nov. 4 | at | *Wisconsin (6-3) | L | 7 | 33 |
| Nov. 11 | vs | *Northwestern (6-3) | L | 14 | 19 |
| Nov. 18 | at | *Minnesota (1-7-1) | L | 14 | 27 |
| Nov. 25 | vs | *Indiana (3-5-1) | W | 13 | 0 |
| | 2-7-0 | | 143 | 200 |
| 1949-Purdue (Western) |
| Sep. 24 | at | *Northwestern (4-5) | L | 6 | 20 |
| Oct. 1 | vs | *Iowa (4-5) | L | 7 | 21 |
| Oct. 8 | vs | Notre Dame (10-0) | L | 12 | 35 |
| Oct. 14 | at | Miami (Florida) (6-3) | W | 14 | 0 |
| Oct. 22 | vs | *Illinois (3-4-2) | L | 0 | 19 |
| Oct. 29 | at | *Minnesota (7-2) | W | 13 | 7 |
| Nov. 5 | at | *Michigan (6-2-1) | L | 12 | 20 |
| Nov. 12 | vs | Marquette (4-5) | W | 41 | 7 |
| Nov. 19 | at | *Indiana (1-8) | W | 14 | 6 |
| | 4-5-0 | | 119 | 135 |
| 1948-Purdue (Western) |
| Sep. 25 | at | Notre Dame (9-0-1) | L | 27 | 28 |
| Oct. 2 | at | *Northwestern (8-2) | L | 0 | 21 |
| Oct. 9 | vs | *Michigan (9-0) | L | 0 | 40 |
| Oct. 16 | at | *Iowa (4-5) | W | 20 | 13 |
| Oct. 23 | at | *Illinois (3-6) | L | 6 | 10 |
| Oct. 30 | vs | Marquette (2-8) | W | 14 | 9 |
| Nov. 6 | at | *Minnesota (7-2) | L | 7 | 34 |
| Nov. 13 | vs | Pittsburgh (6-3) | L | 13 | 20 |
| Nov. 20 | vs | *Indiana (2-7) | W | 39 | 0 |
| | 3-6-0 | | 126 | 175 |
| 1947-Purdue (Western) |
| Sep. 27 | at | *Wisconsin (5-3-1) | L | 14 | 32 |
| Oct. 4 | vs | *Ohio State (2-6-1) | W | 24 | 20 |
| Oct. 11 | vs | Notre Dame (9-0) | L | 7 | 22 |
| Oct. 18 | vs | Boston University (5-3) | W | 62 | 7 | at Boston, MA |
| Oct. 25 | vs | *Illinois (5-3-1) | W | 14 | 7 |
| Nov. 1 | vs | *Iowa (3-5-1) | W | 21 | 0 |
| Nov. 8 | at | *Minnesota (6-3) | L | 21 | 26 |
| Nov. 15 | vs | Pittsburgh (1-8) | W | 28 | 0 |
| Nov. 22 | at | *Indiana (5-3-1) | L | 14 | 16 |
| | 5-4-0 | | 205 | 130 |
| 1946-Purdue (Western) |
| Sep. 21 | vs | Miami (Ohio) ( ) | W | 13 | 7 |
| Sep. 28 | at | *Iowa (5-4) | L | 0 | 16 |
| Oct. 5 | at | *Illinois (8-2) | L | 7 | 43 |
| Oct. 12 | at | Notre Dame (8-0-1) | L | 6 | 49 |
| Oct. 19 | at | *Ohio State (4-3-2) | T | 14 | 14 |
| Oct. 26 | at | Pittsburgh (3-5-1) | W | 10 | 8 |
| Nov. 2 | vs | *Wisconsin (4-5) | L | 20 | 24 |
| Nov. 9 | at | *Minnesota (5-4) | L | 7 | 13 |
| Nov. 23 | vs | *Indiana (6-3) | L | 20 | 34 |
| | 2-6-1 | | 97 | 208 |
| 1945-Purdue (Western) |
| Sep. 22 | vs | Marquette (5-4-1) | W | 14 | 13 |
| Sep. 29 | at | Great Lakes Navy (6-4-1) | W | 20 | 6 |
| Oct. 6 | at | *Wisconsin (3-4-2) | W | 13 | 7 |
| Oct. 13 | vs | *Iowa (2-7) | W | 40 | 0 |
| Oct. 20 | at | *Ohio State (7-2) | W | 35 | 13 |
| Oct. 27 | at | *Northwestern (4-4-1) | L | 14 | 26 |
| Nov. 3 | vs | Pittsburgh (3-7) | W | 28 | 0 |
| Nov. 10 | vs | Miami (Ohio) ( ) | W | 21 | 7 |
| Nov. 17 | at | *Michigan (7-3) | L | 13 | 27 |
| Nov. 24 | at | *Indiana (9-0-1) | L | 0 | 26 |
| | 7-3-0 | | 198 | 125 |
| 1944-Purdue (Western) |
| Sep. 23 | at | Great Lakes Navy (9-2-1) | L | 18 | 27 |
| Sep. 30 | vs | Marquette (1-7) | W | 40 | 7 |
| Oct. 7 | at | *Illinois (5-4-1) | W | 35 | 19 |
| Oct. 14 | vs | Iowa Pre-Flight (10-1) | L | 6 | 13 |
| Oct. 21 | at | *Iowa (1-7) | W | 26 | 7 |
| Oct. 28 | at | *Michigan (8-2) | L | 14 | 40 |
| Nov. 4 | vs | *Wisconsin (3-6) | W | 35 | 0 |
| Nov. 11 | at | *Northwestern (1-7-1) | W | 27 | 7 |
| Nov. 18 | vs | Navy (6-3) | L | 0 | 32 | at Baltimore, MD |
| Nov. 25 | vs | *Indiana (7-3) | L | 6 | 14 |
| | 5-5-0 | | 207 | 166 |
| 1943-Purdue (Western) |
| Sep. 18 | at | Great Lakes Navy (10-2) | W | 23 | 13 |
| Sep. 25 | at | Marquette (3-4-1) | W | 21 | 0 |
| Oct. 2 | vs | *Illinois (3-7) | W | 40 | 21 |
| Oct. 9 | vs | Camp Grant (2-6-2) | W | 19 | 0 |
| Oct. 16 | vs | *Ohio State (3-6) | W | 30 | 7 | at Cleveland, OH |
| Oct. 23 | vs | *Iowa (1-6-1) | W | 28 | 7 |
| Oct. 30 | at | *Wisconsin (1-9) | W | 32 | 0 |
| Nov. 6 | at | *Minnesota (5-4) | W | 14 | 7 |
| Nov. 20 | at | *Indiana (4-4-2) | W | 7 | 0 |
| | 9-0-0 | | 214 | 55 |
| 1942-Purdue (Western) |
| Sep. 26 | vs | Fordham (5-3-1) | L | 7 | 14 |
| Oct. 3 | at | Vanderbilt (6-4) | L | 0 | 26 |
| Oct. 10 | at | *Northwestern (1-9) | W | 7 | 6 |
| Oct. 17 | at | *Ohio State (9-1) | L | 0 | 26 |
| Oct. 24 | vs | *Wisconsin (8-1-1) | L | 0 | 13 |
| Oct. 31 | at | *Iowa (6-4) | L | 7 | 13 |
| Nov. 7 | vs | Great Lakes Navy (8-3-1) | L | 0 | 42 |
| Nov. 14 | at | Michigan State (4-3-2) | L | 6 | 19 |
| Nov. 21 | vs | *Indiana (7-3) | L | 0 | 20 |
| | 1-8-0 | | 27 | 179 |
| 1941-Purdue (Western) |
| Sep. 27 | vs | Vanderbilt (8-2) | L | 0 | 3 |
| Oct. 4 | at | Pittsburgh (3-6) | W | 6 | 0 |
| Oct. 18 | at | *Ohio State (6-1-1) | L | 14 | 16 |
| Oct. 25 | vs | *Iowa (3-5) | W | 7 | 6 |
| Nov. 1 | vs | Fordham (8-1) | L | 0 | 17 | at New York, NY |
| Nov. 8 | vs | Michigan State (5-3-1) | T | 0 | 0 |
| Nov. 15 | at | *Wisconsin (3-5) | L | 0 | 13 |
| Nov. 22 | at | *Indiana (2-6) | L | 0 | 7 |
| | 2-5-1 | | 27 | 62 |
| 1940-Purdue (Western) |
| Sep. 28 | vs | Butler ( ) | W | 28 | 0 |
| Oct. 5 | at | *Ohio State (4-4) | L | 14 | 17 |
| Oct. 12 | at | Michigan State (3-4-1) | L | 7 | 20 |
| Oct. 26 | vs | *Wisconsin (4-4) | L | 13 | 14 |
| Nov. 2 | at | *Iowa (4-4) | W | 21 | 6 |
| Nov. 9 | vs | Fordham (7-2) | L | 7 | 13 | at New York, NY |
| Nov. 16 | at | *Minnesota (8-0) | L | 6 | 33 |
| Nov. 23 | vs | *Indiana (3-5) | L | 0 | 3 |
| | 2-6-0 | | 96 | 106 |
| 1939-Purdue (Western) |
| Sep. 30 | at | Notre Dame (7-2) | L | 0 | 3 |
| Oct. 14 | at | *Minnesota (3-4-1) | T | 13 | 13 |
| Oct. 21 | vs | Michigan State (4-4-1) | W | 20 | 7 |
| Oct. 28 | at | Santa Clara (5-1-3) | L | 6 | 13 |
| Nov. 4 | vs | *Iowa (6-1-1) | L | 0 | 4 |
| Nov. 11 | at | *Northwestern (3-4-1) | W | 3 | 0 |
| Nov. 18 | at | *Wisconsin (1-6-1) | T | 7 | 7 |
| Nov. 25 | at | *Indiana (2-4-2) | W | 7 | 6 |
| | 3-3-2 | | 56 | 53 |
| 1938-Purdue (Western) |
| Sep. 24 | vs | Detroit Mercy (6-4) | W | 19 | 6 |
| Oct. 1 | at | Butler ( ) | W | 21 | 6 |
| Oct. 8 | at | *Minnesota (6-2) | L | 0 | 7 |
| Oct. 15 | vs | Fordham (6-1-2) | T | 6 | 6 | at New York, NY |
| Oct. 22 | vs | *Wisconsin (5-3) | W | 13 | 7 |
| Oct. 29 | at | *Iowa (1-6-1) | T | 0 | 0 |
| Nov. 5 | at | *Ohio State (4-3-1) | W | 12 | 0 |
| Nov. 19 | vs | *Indiana (1-6-1) | W | 13 | 6 |
| | 5-1-2 | | 84 | 38 |
| 1937-Purdue (Western) |
| Sep. 25 | vs | Butler ( ) | W | 33 | 7 |
| Oct. 2 | at | *Ohio State (6-2) | L | 0 | 13 |
| Oct. 9 | vs | Carnegie Tech (2-5-1) | W | 7 | 0 |
| Oct. 16 | at | *Northwestern (4-4) | L | 7 | 14 |
| Oct. 30 | vs | *Iowa (1-7) | W | 13 | 0 |
| Nov. 6 | vs | Fordham (7-0-1) | L | 3 | 21 | at New York, NY |
| Nov. 13 | at | *Wisconsin (4-3-1) | T | 7 | 7 |
| Nov. 20 | at | *Indiana (5-3) | W | 13 | 7 |
| | 4-3-1 | | 83 | 69 |
| 1936-Purdue (Western) |
| Sep. 26 | vs | Ohio ( ) | W | 47 | 0 |
| Oct. 10 | vs | *Wisconsin (2-6) | W | 35 | 14 |
| Oct. 17 | at | *Chicago (2-5-1) | W | 35 | 7 |
| Oct. 24 | at | *Minnesota (7-1) | L | 0 | 33 |
| Oct. 31 | at | Carnegie Tech (2-6) | W | 7 | 6 |
| Nov. 7 | vs | Fordham (5-1-2) | L | 0 | 15 | at New York, NY |
| Nov. 14 | at | *Iowa (3-4-1) | W | 13 | 0 |
| Nov. 21 | vs | *Indiana (5-2-1) | T | 20 | 20 |
| | 5-2-1 | | 157 | 95 |
| 1935-Purdue (Western) |
| Oct. 5 | at | *Northwestern (4-3-1) | W | 7 | 0 |
| Oct. 12 | vs | Fordham (6-1-2) | W | 20 | 0 | at New York, NY |
| Oct. 19 | at | *Chicago (4-4) | W | 19 | 0 |
| Oct. 26 | vs | Carnegie Tech (2-5-1) | L | 0 | 7 |
| Nov. 2 | at | *Minnesota (8-0) | L | 7 | 29 |
| Nov. 9 | at | *Wisconsin (1-7) | L | 0 | 8 |
| Nov. 16 | vs | *Iowa (4-2-2) | W | 12 | 6 |
| Nov. 23 | at | *Indiana (4-3-1) | L | 0 | 7 |
| | 4-4-0 | | 65 | 57 |
| 1934-Purdue (Western) |
| Oct. 6 | vs | Rice (9-1-1) | L | 0 | 14 |
| Oct. 13 | at | Notre Dame (6-3) | L | 7 | 18 |
| Oct. 20 | vs | *Wisconsin (4-4) | W | 14 | 0 |
| Oct. 27 | at | Carnegie Tech (4-5) | W | 20 | 0 |
| Nov. 3 | at | *Chicago (4-4) | W | 26 | 20 |
| Nov. 10 | at | *Iowa (2-5-1) | W | 13 | 6 |
| Nov. 17 | vs | Fordham (5-3) | W | 7 | 0 | at New York, NY |
| Nov. 24 | vs | *Indiana (3-3-2) | L | 6 | 17 |
| | 5-3-0 | | 93 | 75 |
| 1933-Purdue (Western) |
| Oct. 7 | vs | Ohio ( ) | W | 13 | 6 |
| Oct. 14 | at | *Minnesota (4-0-4) | T | 7 | 7 |
| Oct. 21 | at | *Chicago (3-3-2) | W | 14 | 0 |
| Oct. 28 | at | *Wisconsin (2-5-1) | W | 14 | 0 |
| Nov. 4 | vs | Carnegie Tech (4-3-2) | W | 17 | 7 |
| Nov. 11 | at | Notre Dame (3-5-1) | W | 19 | 0 |
| Nov. 18 | vs | *Iowa (5-3) | L | 6 | 14 |
| Nov. 25 | at | *Indiana (1-5-2) | W | 19 | 3 |
| | 6-1-1 | | 109 | 37 |
| 1932-Purdue (Western) |
| Oct. 1 | vs | Kansas State (4-4) | W | 29 | 13 |
| Oct. 8 | at | *Minnesota (5-3) | W | 7 | 0 |
| Oct. 15 | vs | *Wisconsin (6-1-1) | W | 7 | 6 |
| Oct. 22 | at | *Northwestern (3-4-1) | T | 7 | 7 |
| Oct. 29 | vs | New York University (5-3) | W | 34 | 9 | at Bronx, NY |
| Nov. 5 | at | *Chicago (3-4-1) | W | 37 | 0 |
| Nov. 12 | at | *Iowa (1-7) | W | 18 | 0 |
| Nov. 19 | vs | *Indiana (3-4-1) | W | 25 | 7 |
| | 7-0-1 | | 164 | 42 |
| 1931-Purdue (Western) |
| Oct. 3 | vs | Western Reserve ( ) | W | 28 | 0 |
| Oct. 3 | vs | Coe ( ) | W | 19 | 0 |
| Oct. 10 | vs | *Illinois (2-6) | W | 7 | 0 |
| Oct. 17 | at | *Wisconsin (5-4-1) | L | 14 | 21 |
| Oct. 24 | at | Carnegie Tech (3-5-1) | W | 13 | 6 |
| Oct. 31 | at | *Chicago (2-6-1) | W | 14 | 6 |
| Nov. 7 | vs | Centenary (5-5) | W | 49 | 6 |
| Nov. 14 | vs | *Iowa (1-6-1) | W | 22 | 0 |
| Nov. 21 | at | *Indiana (2-5-1) | W | 19 | 0 |
| Nov. 28 | vs | *Northwestern (7-1-1) | W | 7 | 0 | at Chicago, IL |
| | 9-1-0 | | 192 | 39 |
| 1930-Purdue (Western) |
| Oct. 4 | vs | Baylor (6-3-1) | W | 20 | 7 |
| Oct. 11 | at | *Michigan (8-0-1) | L | 13 | 14 |
| Oct. 18 | at | *Iowa (4-4) | W | 20 | 0 |
| Oct. 25 | vs | *Wisconsin (6-2-1) | W | 7 | 6 |
| Nov. 1 | at | *Illinois (3-5) | W | 25 | 0 |
| Nov. 8 | at | *Chicago (2-5-2) | W | 26 | 7 |
| Nov. 15 | vs | Butler ( ) | W | 33 | 0 |
| Nov. 22 | vs | *Indiana (2-5-1) | L | 6 | 7 |
| | 6-2-0 | | 150 | 41 |
| 1929-Purdue (Western) |
| Oct. 5 | vs | Kansas State (3-5) | W | 26 | 14 |
| Oct. 12 | vs | *Michigan (5-3-1) | W | 30 | 16 |
| Oct. 19 | vs | DePauw ( ) | W | 26 | 7 |
| Oct. 26 | at | *Chicago (7-3) | W | 26 | 0 |
| Nov. 2 | at | *Wisconsin (4-5) | W | 13 | 0 |
| Nov. 9 | vs | Mississippi (1-6-2) | W | 27 | 7 |
| Nov. 16 | vs | *Iowa (4-2-2) | W | 7 | 0 |
| Nov. 23 | at | *Indiana (2-6-1) | W | 32 | 0 |
| | 8-0-0 | | 187 | 44 |
| 1928-Purdue (Western) |
| Oct. 6 | vs | DePauw ( ) | W | 31 | 0 |
| Oct. 13 | at | *Minnesota (6-2) | L | 0 | 15 |
| Oct. 20 | vs | *Wisconsin (7-1-1) | T | 19 | 19 |
| Oct. 27 | at | *Chicago (2-7) | W | 40 | 0 |
| Nov. 3 | vs | Case ( ) | W | 19 | 0 |
| Nov. 10 | at | *Northwestern (5-3) | L | 6 | 7 |
| Nov. 17 | vs | Wabash ( ) | W | 14 | 0 |
| Nov. 24 | vs | *Indiana (4-4) | W | 14 | 0 |
| | 5-2-1 | | 143 | 41 |
| 1927-Purdue (Western) |
| Oct. 1 | vs | DePauw ( ) | W | 15 | 0 |
| Oct. 8 | at | Harvard (4-4) | W | 19 | 0 |
| Oct. 15 | at | *Chicago (4-4) | L | 6 | 7 |
| Oct. 22 | at | *Wisconsin (4-4) | L | 6 | 12 |
| Oct. 29 | vs | Montana State (4-4) | W | 39 | 7 |
| Nov. 5 | vs | *Northwestern (4-4) | W | 18 | 6 |
| Nov. 12 | vs | Franklin ( ) | W | 46 | 0 |
| Nov. 19 | at | *Indiana (3-4-1) | W | 21 | 6 |
| | 6-2-0 | | 170 | 38 |
| 1926-Purdue (Western) |
| Oct. 2 | at | Navy (9-0-1) | L | 13 | 17 |
| Oct. 9 | vs | Wabash ( ) | W | 21 | 14 |
| Oct. 16 | vs | *Wisconsin (5-2-1) | T | 0 | 0 |
| Oct. 23 | at | *Chicago (2-6) | W | 6 | 0 |
| Oct. 30 | vs | Indiana State ( ) | W | 38 | 0 |
| Nov. 6 | at | *Northwestern (7-1) | L | 0 | 22 |
| Nov. 13 | vs | Franklin ( ) | W | 44 | 0 |
| Nov. 20 | vs | *Indiana (3-5) | W | 24 | 14 |
| | 5-2-1 | | 146 | 67 |
| 1925-Purdue (Western) |
| Oct. 3 | vs | Wabash ( ) | L | 7 | 13 |
| Oct. 10 | vs | DePauw ( ) | W | 39 | 0 |
| Oct. 17 | vs | Rose-Hulman ( ) | W | 44 | 0 |
| Oct. 24 | at | *Wisconsin (6-1-1) | L | 0 | 7 |
| Oct. 31 | at | *Chicago (3-4-1) | L | 0 | 6 |
| Nov. 7 | vs | Franklin ( ) | W | 20 | 0 |
| Nov. 14 | vs | *Northwestern (5-3) | L | 9 | 13 |
| Nov. 21 | at | *Indiana (3-4-1) | T | 0 | 0 |
| | 3-4-1 | | 119 | 39 |
| 1924-Purdue (Western) |
| Sep. 27 | vs | Wabash ( ) | W | 21 | 7 |
| Oct. 4 | at | *Ohio State (2-3-3) | L | 0 | 7 |
| Oct. 11 | vs | Rose-Hulman ( ) | W | 41 | 3 |
| Oct. 18 | at | *Northwestern (4-4) | W | 7 | 3 |
| Nov. 1 | at | *Chicago (4-1-3) | L | 6 | 19 |
| Nov. 8 | vs | DePauw ( ) | W | 36 | 0 |
| Nov. 22 | vs | *Indiana (4-4) | W | 26 | 7 |
| | 5-2-0 | | 137 | 46 |
| 1923-Purdue (Western) |
| Oct. 6 | vs | Wilmington ( ) | W | 39 | 0 |
| Oct. 13 | at | *Iowa (5-3) | L | 0 | 7 |
| Oct. 20 | vs | Wabash ( ) | T | 7 | 7 |
| Oct. 27 | at | *Chicago (7-1) | L | 6 | 20 |
| Nov. 3 | at | Notre Dame (9-1) | L | 7 | 34 |
| Nov. 10 | vs | *Ohio State (3-4-1) | L | 0 | 32 |
| Nov. 17 | vs | *Northwestern (2-6) | W | 6 | 3 |
| Nov. 24 | at | *Indiana (3-4) | L | 0 | 3 |
| | 2-5-1 | | 65 | 106 |
| 1922-Purdue (Western) |
| Oct. 7 | vs | James Millikin ( ) | W | 10 | 0 |
| Oct. 14 | vs | Notre Dame (8-1-1) | L | 0 | 20 |
| Oct. 21 | at | *Chicago (5-1-1) | L | 0 | 12 |
| Oct. 28 | at | *Iowa (7-0) | L | 0 | 56 |
| Nov. 4 | vs | Wabash ( ) | L | 6 | 7 |
| Nov. 11 | at | *Northwestern (3-3-1) | L | 13 | 24 |
| Nov. 25 | vs | *Indiana (1-4-2) | T | 7 | 7 |
| | 1-5-1 | | 36 | 126 |
| 1921-Purdue (Western) |
| Oct. 1 | vs | Wabash ( ) | L | 0 | 9 |
| Oct. 8 | at | *Chicago (6-1) | L | 0 | 9 |
| Oct. 15 | vs | Notre Dame (10-1) | L | 0 | 33 |
| Oct. 29 | vs | *Iowa (7-0) | L | 6 | 13 |
| Nov. 5 | vs | *Northwestern (1-6) | W | 3 | 0 |
| Nov. 12 | at | *Ohio State (5-2) | L | 0 | 28 |
| Nov. 19 | at | *Indiana (3-4) | L | 0 | 3 |
| | 1-6-0 | | 9 | 95 |
| 1920-Purdue (Western) |
| Oct. 2 | vs | DePauw ( ) | W | 10 | 0 |
| Oct. 9 | at | *Chicago (3-4) | L | 0 | 20 |
| Oct. 16 | at | *Ohio State (7-1) | L | 0 | 17 |
| Oct. 30 | vs | Wabash ( ) | W | 19 | 14 |
| Nov. 6 | at | Notre Dame (9-0) | L | 0 | 28 |
| Nov. 13 | at | *Northwestern (3-4) | L | 0 | 14 |
| Nov. 20 | vs | *Indiana (5-2) | L | 7 | 10 |
| | 2-5-0 | | 36 | 103 |
| 1919-Purdue (Western) |
| Oct. 4 | vs | Franklin ( ) | T | 14 | 14 |
| Oct. 11 | vs | *Illinois (6-1) | L | 7 | 14 |
| Oct. 18 | at | *Chicago (5-2) | L | 0 | 16 |
| Nov. 1 | vs | Michigan State ( ) | W | 13 | 7 |
| Nov. 8 | at | *Ohio State (6-1) | L | 0 | 20 |
| Nov. 17 | vs | DePauw ( ) | W | 24 | 0 |
| Nov. 22 | vs | Notre Dame (9-0) | L | 13 | 33 |
| | 2-4-1 | | 71 | 104 |
| 1918-Purdue (Western) |
| Oct. 26 | vs | DePauw ( ) | L | 7 | 9 |
| Nov. 2 | vs | *Chicago (4-6-1) | W | 7 | 3 |
| Nov. 9 | at | Michigan State (4-3) | W | 14 | 6 |
| Nov. 16 | vs | Wabash ( ) | W | 53 | 6 | at Indianapolis, IN |
| Nov. 23 | vs | Notre Dame (3-1-2) | L | 6 | 26 |
| Nov. 30 | vs | Great Lakes Navy (6-0-2) | L | 0 | 27 | at Evanston, IL |
| | 3-3-0 | | 87 | 77 |
| 1917-Purdue (Western) |
| Oct. 6 | vs | Franklin ( ) | W | 54 | 0 |
| Oct. 13 | vs | DePauw ( ) | W | 7 | 6 |
| Oct. 20 | at | *Chicago (3-2-1) | L | 0 | 27 |
| Oct. 27 | at | *Illinois (5-2-1) | L | 0 | 27 |
| Nov. 3 | vs | *Northwestern (5-2) | L | 6 | 12 |
| Nov. 17 | vs | Wabash ( ) | W | 28 | 0 |
| Nov. 24 | vs | *Indiana (5-2) | L | 0 | 37 |
| | 3-4-0 | | 95 | 109 |
| 1916-Purdue (Western) |
| Oct. 7 | vs | DePauw ( ) | W | 13 | 0 |
| Oct. 14 | vs | Wabash ( ) | W | 28 | 7 |
| Oct. 21 | at | *Iowa (4-3) | L | 6 | 24 |
| Oct. 28 | vs | *Illinois (3-3-1) | L | 7 | 14 |
| Nov. 4 | at | *Chicago (3-4) | L | 7 | 16 |
| Nov. 18 | at | *Northwestern (6-1) | L | 6 | 38 |
| Nov. 25 | vs | *Indiana (2-4-1) | T | 0 | 0 |
| | 2-4-1 | | 67 | 99 |
| 1915-Purdue (Western) |
| Oct. 2 | vs | Wabash ( ) | T | 7 | 7 |
| Oct. 9 | vs | Beloit ( ) | W | 26 | 0 |
| Oct. 16 | vs | *Wisconsin (4-3) | L | 3 | 28 |
| Oct. 23 | at | *Chicago (5-2) | L | 0 | 7 |
| Nov. 6 | vs | *Iowa (3-4) | W | 19 | 13 |
| Nov. 13 | at | Kentucky (6-1-1) | L | 0 | 7 |
| Nov. 20 | at | *Indiana (3-3-1) | W | 7 | 0 |
| | 3-3-1 | | 62 | 62 |
| 1914-Purdue (Western) |
| Oct. 3 | vs | Wabash ( ) | W | 27 | 3 |
| Oct. 10 | vs | Western Reserve ( ) | W | 26 | 0 |
| Oct. 17 | at | *Wisconsin (4-2-1) | L | 7 | 14 |
| Oct. 24 | at | *Chicago (4-2-1) | L | 0 | 21 |
| Nov. 7 | vs | Kentucky ( ) | W | 40 | 6 |
| Nov. 14 | at | *Northwestern (1-6) | W | 34 | 6 |
| Nov. 21 | vs | *Indiana (3-4) | W | 23 | 13 |
| | 5-2-0 | | 157 | 63 |
| 1913-Purdue (Western) |
| Oct. 4 | vs | Wabash ( ) | W | 26 | 0 |
| Oct. 11 | vs | *Northwestern (1-6) | W | 34 | 0 |
| Oct. 18 | vs | *Wisconsin (3-3-1) | T | 7 | 7 |
| Oct. 25 | at | *Chicago (7-0) | L | 0 | 6 |
| Nov. 8 | vs | Rose-Hulman ( ) | W | 62 | 0 |
| Nov. 15 | at | *Illinois (4-2-1) | T | 0 | 0 |
| Nov. 23 | at | *Indiana (3-4) | W | 42 | 7 |
| | 4-1-2 | | 171 | 20 |
| 1912-Purdue (Western) |
| Oct. 5 | vs | DePauw ( ) | W | 21 | 0 |
| Oct. 19 | at | *Wisconsin (7-0) | L | 0 | 41 |
| Oct. 26 | at | *Chicago (6-1) | L | 0 | 7 |
| Nov. 2 | at | *Northwestern (2-3-1) | W | 21 | 6 |
| Nov. 9 | vs | *Illinois (3-3-1) | T | 9 | 9 |
| Nov. 17 | vs | Rose-Hulman ( ) | W | 91 | 0 |
| Nov. 24 | vs | *Indiana (2-5) | W | 34 | 7 |
| | 4-2-1 | | 176 | 70 |
| 1911-Purdue (Western) |
| Oct. 8 | vs | Wabash ( ) | L | 0 | 3 |
| Oct. 14 | at | *Chicago (6-1) | L | 3 | 11 |
| Oct. 28 | vs | DePauw ( ) | W | 5 | 0 |
| Nov. 4 | at | *Illinois (4-2-1) | L | 3 | 12 |
| Nov. 11 | vs | *Iowa (3-4) | L | 0 | 11 |
| Nov. 18 | vs | Rose-Hulman ( ) | W | 35 | 6 |
| Nov. 25 | at | *Indiana (3-3-1) | W | 12 | 5 |
| | 3-4-0 | | 58 | 48 |
| 1910-Purdue (Western) |
| Oct. 8 | vs | Wabash ( ) | L | 0 | 3 |
| Oct. 22 | at | *Iowa (5-2) | L | 0 | 16 |
| Oct. 29 | vs | *Illinois (7-0) | L | 0 | 11 |
| Nov. 5 | at | *Chicago (2-5) | L | 5 | 14 |
| Nov. 12 | vs | DePauw ( ) | W | 14 | 6 |
| Nov. 19 | vs | *Indiana (6-1) | L | 0 | 15 |
| | 1-5-0 | | 19 | 65 |
| 1909-Purdue (Western) |
| Oct. 2 | at | *Chicago (4-1-2) | L | 0 | 40 |
| Oct. 9 | vs | *Northwestern (1-3-1) | L | 5 | 14 |
| Oct. 16 | vs | DePauw ( ) | W | 15 | 12 |
| Oct. 30 | at | *Illinois (5-2) | L | 6 | 24 |
| Nov. 6 | vs | Wabash ( ) | L | 17 | 18 |
| Nov. 13 | vs | Rose-Hulman ( ) | W | 26 | 3 |
| Nov. 20 | vs | *Indiana (4-3) | L | 3 | 36 |
| | 2-5-0 | | 72 | 147 |
| 1908-Purdue (Western) |
| Oct. 3 | at | *Chicago (5-0-1) | L | 0 | 39 |
| Oct. 10 | vs | Earlham ( ) | W | 40 | 0 |
| Oct. 17 | vs | Monmouth ( ) | W | 30 | 0 |
| Oct. 31 | vs | DePauw ( ) | W | 28 | 4 |
| Nov. 7 | at | *Northwestern (2-2) | W | 16 | 10 |
| Nov. 14 | vs | *Illinois (5-1-1) | L | 6 | 15 |
| Nov. 21 | vs | *Indiana (3-4) | L | 4 | 10 |
| | 4-3-0 | | 124 | 78 |
| 1907-Purdue (Western) |
| Oct. 12 | vs | Wabash ( ) | L | 0 | 2 |
| Nov. 2 | at | *Illinois (3-2) | L | 4 | 21 |
| Nov. 9 | at | *Chicago (4-1) | L | 0 | 56 |
| Nov. 16 | vs | *Wisconsin (3-1-1) | L | 6 | 12 |
| Nov. 23 | vs | Notre Dame ( ) | L | 0 | 17 |
| | 0-5-0 | | 10 | 108 |
| 1906-Purdue (Western) |
| Oct. 20 | at | *Chicago (4-1) | L | 0 | 39 |
| Oct. 27 | vs | Wabash ( ) | L | 0 | 11 |
| Nov. 3 | vs | Notre Dame ( ) | L | 0 | 2 |
| Nov. 17 | at | *Wisconsin (5-0) | L | 5 | 29 |
| Nov. 25 | vs | *Illinois (1-3-1) | L | 0 | 5 |
| | 0-5-0 | | 5 | 86 |
| 1905-Purdue (Western) |
| Sep. 23 | vs | Wendell Phillips High ( ) | W | 33 | 0 |
| Sep. 30 | vs | Beloit (3-6-1) | W | 36 | 0 |
| Oct. 14 | at | Wabash (4-5) | W | 12 | 0 |
| Oct. 21 | at | *Illinois (5-4) | W | 29 | 0 |
| Oct. 28 | vs | *Indiana (8-1-1) | T | 11 | 11 | at Indianapolis, IN |
| Nov. 4 | vs | Missouri (5-4) | W | 24 | 0 |
| Nov. 11 | at | *Chicago (11-0) | L | 0 | 19 |
| Nov. 24 | vs | Notre Dame (5-4) | W | 32 | 0 |
| | 6-1-1 | | 177 | 30 |
| 1904-Purdue (Western) |
| Sep. 17 | vs | Purdue Alumni ( ) | L | 2 | 6 |
| Sep. 24 | vs | North Division High ( ) | W | 5 | 0 |
| Sep. 28 | vs | Beloit (4-4-1) | W | 11 | 0 |
| Oct. 1 | at | Earlham ( ) | W | 28 | 11 |
| Oct. 8 | at | *Chicago (10-1-1) | L | 0 | 20 |
| Oct. 15 | vs | Wabash (4-4) | W | 6 | 0 |
| Oct. 22 | vs | *Illinois (9-2-1) | L | 6 | 24 |
| Oct. 28 | vs | Missouri (3-6) | W | 11 | 0 | at St. Louis, MO |
| Nov. 5 | vs | Indiana Medical ( ) | W | 34 | 5 |
| Nov. 12 | vs | *Indiana (6-4) | W | 27 | 0 | at Indianapolis, IN |
| Nov. 19 | at | Culver ( ) | W | 10 | 0 |
| Nov. 24 | vs | Notre Dame (5-3) | W | 36 | 0 |
| | 9-3-0 | | 176 | 66 |
| 1903-Purdue (Western) |
| Sep. 26 | vs | Englewood High ( ) | W | 34 | 0 |
| Oct. 1 | at | Wabash ( ) | W | 18 | 0 |
| Oct. 3 | vs | Beloit (3-7) | W | 17 | 0 |
| Oct. 10 | at | *Chicago (12-2-1) | L | 0 | 22 |
| Oct. 17 | vs | *Illinois (8-6) | L | 0 | 24 |
| Oct. 24 | vs | Oberlin ( ) | W | 18 | 2 |
| | 4-2-0 | | 87 | 48 |
| 1902-Purdue (Western) |
| Sep. 27 | vs | Franklin ( ) | W | 56 | 0 |
| Oct. 4 | vs | DePauw ( ) | W | 39 | 0 |
| Oct. 11 | at | *Chicago (14-1) | L | 0 | 33 |
| Oct. 18 | at | *Illinois (10-2-1) | L | 5 | 29 |
| Oct. 25 | vs | Case ( ) | W | 5 | 0 |
| Nov. 1 | at | *Northwestern (6-6) | W | 5 | 0 |
| Nov. 8 | at | Greer ( ) | W | 73 | 0 |
| Nov. 15 | vs | *Indiana (3-5-1) | W | 39 | 0 |
| Nov. 22 | vs | Butler ( ) | W | 87 | 0 |
| Nov. 27 | vs | Notre Dame (6-2-1) | T | 6 | 6 |
| | 7-2-1 | | 315 | 68 |
| 1901-Purdue (Western) |
| Sep. 28 | vs | Franklin ( ) | W | 24 | 0 |
| Oct. 5 | vs | Wabash ( ) | W | 45 | 0 |
| Oct. 12 | at | *Chicago (8-6-2) | T | 5 | 5 |
| Oct. 19 | vs | DePauw ( ) | W | 19 | 0 |
| Oct. 26 | at | *Indiana (6-3) | L | 6 | 11 |
| Nov. 2 | vs | Case ( ) | W | 22 | 0 |
| Nov. 9 | at | Notre Dame (8-1-1) | L | 6 | 12 |
| Nov. 16 | vs | *Illinois (8-2) | L | 6 | 28 |
| Nov. 28 | vs | *Northwestern (8-2-1) | L | 5 | 10 |
| | 4-4-1 | | 138 | 66 |
| 1900-Purdue (Western) |
| Sep. 29 | vs | Illinois Wesleyan ( ) | W | 39 | 0 |
| Oct. 6 | at | *Chicago (9-5-1) | L | 5 | 17 |
| Oct. 13 | vs | DePauw ( ) | W | 28 | 5 |
| Oct. 20 | at | *Michigan (7-2-1) | L | 6 | 11 |
| Oct. 27 | vs | Rose-Hulman ( ) | W | 46 | 5 |
| Nov. 3 | at | *Illinois (7-3-2) | L | 5 | 17 |
| Nov. 17 | vs | Earlham ( ) | W | 38 | 0 |
| Nov. 29 | vs | *Indiana (4-2-2) | L | 5 | 24 |
| | 4-4-0 | | 172 | 79 |
| 1899-Purdue (Western) |
| Sep. 30 | vs | Purdue Alumni ( ) | W | 10 | 5 |
| Oct. 7 | vs | Earlham ( ) | W | 30 | 5 |
| Oct. 14 | at | Oberlin ( ) | L | 0 | 12 |
| Oct. 28 | vs | DePauw ( ) | W | 40 | 0 |
| Nov. 4 | at | *Chicago (16-0-2) | L | 0 | 44 |
| Nov. 18 | vs | Notre Dame (6-3-1) | T | 10 | 10 |
| Nov. 22 | at | *Illinois (3-5-1) | W | 5 | 0 |
| Nov. 25 | at | *Northwestern (7-6) | L | 0 | 29 |
| Nov. 30 | vs | Indiana (6-2) | L | 5 | 17 |
| | 4-4-1 | | 100 | 122 |
| 1898-Purdue (Western) |
| Oct. 8 | vs | Purdue Alumni ( ) | L | 0 | 6 |
| Oct. 18 | at | Haskell ( ) | W | 5 | 0 |
| Oct. 22 | vs | Haskell ( ) | W | 15 | 0 |
| Nov. 5 | at | *Chicago (14-2-1) | L | 0 | 17 |
| Nov. 12 | vs | Indiana ( ) | W | 14 | 0 |
| Nov. 24 | vs | Oberlin ( ) | L | 0 | 10 |
| | 3-3-0 | | 34 | 33 |
| 1897-Purdue (Western) |
| Oct. 2 | vs | Illinois State ( ) | W | 28 | 0 |
| Oct. 9 | vs | Oberlin ( ) | L | 6 | 22 |
| Oct. 16 | at | DePauw ( ) | W | 8 | 0 |
| Oct. 23 | at | *Illinois (6-2) | L | 4 | 34 |
| Oct. 30 | vs | Indiana ( ) | W | 20 | 6 |
| Nov. 6 | at | *Michigan (6-1-1) | L | 4 | 34 |
| Nov. 13 | vs | Missouri ( ) | W | 30 | 12 |
| Nov. 20 | vs | *Minnesota (4-4) | W | 6 | 0 |
| Nov. 25 | vs | Purdue Alumni ( ) | T | 0 | 0 |
| | 5-3-1 | | 106 | 108 |
| 1896-Purdue (Western) |
| Oct. 3 | vs | Greer ( ) | W | 36 | 0 |
| Oct. 10 | vs | Rush Medical ( ) | W | 32 | 4 |
| Oct. 17 | at | *Minnesota (8-2) | L | 0 | 14 |
| Oct. 24 | vs | *Michigan (9-1) | L | 0 | 16 |
| Nov. 7 | at | DePauw ( ) | W | 22 | 0 |
| Nov. 14 | at | Notre Dame ( ) | W | 28 | 22 |
| Nov. 25 | vs | *Illinois (4-2-1) | T | 4 | 4 |
| | 4-2-1 | | 122 | 60 |
| 1895-Purdue (Independent) |
| Sep. 26 | vs | Iowa State (3-4) | W | 6 | 0 |
| Oct. 12 | vs | Kentucky ( ) | W | 32 | 0 |
| Oct. 19 | vs | Missouri ( ) | L | 6 | 16 | at St. Louis, MO |
| Oct. 29 | vs | Minnesota (7-3) | W | 16 | 4 |
| Nov. 2 | vs | Northwestern (6-5) | L | 6 | 24 |
| Nov. 16 | at | Michigan (8-1) | L | 10 | 12 |
| Nov. 28 | vs | Illinois (4-2-1) | W | 6 | 2 |
| | 4-3-0 | | 82 | 58 |
| 1894-Purdue (Independent) |
| Oct. 6 | vs | Indianapolis Artillery ( ) | W | 6 | 4 |
| Oct. 13 | at | Butler ( ) | W | 30 | 0 |
| Oct. 15 | at | Wisconsin (5-2) | W | 6 | 0 |
| Oct. 20 | vs | Armour ( ) | W | 36 | 0 |
| Oct. 27 | at | Minnesota (3-1) | L | 0 | 24 |
| Nov. 3 | at | Chicago (14-7-1) | W | 10 | 6 |
| Nov. 17 | at | Illinois (4-3) | W | 22 | 2 |
| Nov. 24 | at | Wabash ( ) | W | 44 | 0 |
| Nov. 29 | at | DePauw ( ) | W | 28 | 0 |
| | 8-1-0 | | 182 | 36 |
| 1893-Purdue (Independent) |
| Oct. 14 | vs | Indiana ( ) | W | 64 | 0 |
| Oct. 21 | vs | Butler ( ) | W | 96 | 0 |
| Oct. 25 | vs | Chicago (6-4-2) | W | 20 | 10 |
| Nov. 4 | vs | Wabash ( ) | W | 48 | 8 |
| Nov. 11 | vs | Michigan (7-3) | L | 8 | 46 |
| Nov. 18 | at | Wisconsin (4-2) | L | 30 | 36 |
| Nov. 25 | vs | Illinois (3-2-3) | T | 26 | 26 |
| Nov. 30 | vs | DePauw ( ) | W | 42 | 18 | at Indianapolis, IN |
| | 5-2-1 | | 334 | 144 |
| 1892-Purdue (Independent) |
| Oct. 8 | at | Illinois (7-4-1) | W | 12 | 6 |
| Oct. 15 | at | Wabash ( ) | W | 72 | 0 |
| Oct. 19 | vs | Wisconsin (4-3) | W | 32 | 4 |
| Oct. 24 | vs | Michigan (7-5) | W | 24 | 0 |
| Oct. 29 | vs | Butler ( ) | W | 40 | 6 |
| Nov. 5 | vs | Indiana ( ) | W | 68 | 0 |
| Nov. 19 | vs | Chicago (8-4-1) | W | 38 | 0 |
| Nov. 24 | at | DePauw ( ) | W | 32 | 6 |
| | 8-0-0 | | 318 | 22 |
