Ferguson, who played just three quarters, completed 34 of 48 passes and the Tigers put up 711 yards of total offense.
The seven touchdown by Ferguson tied Paxton Lynch's school and conference record. Ferguson was 26 of 37 for 325 yards and five touchdowns in the first half alone.
Miller had 15 receptions for 224 yards for Memphis (4-1, 1-1 American Athletic Conference). His four TD catches also tied a conference record.